DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Uba2 and aos-1

DIOPT Version :9

Sequence 1:	NP_524756.2	Gene:	Uba2 / 44496	FlyBaseID:	FBgn0029113	Length:	700	Species:	Drosophila melanogaster
Sequence 2:	NP_505604.2	Gene:	aos-1 / 179409	WormBaseID:	WBGene00000142	Length:	350	Species:	Caenorhabditis elegans

Alignment Length:	160	Identity:	39/160 - (24%)
Similarity:	66/160 - (41%)	Gaps:	14/160 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 QELVKKSKVLVVGAGGIGCEVLKNLVLSGFTDIEIIDLDTIDLSNLNRQFLFHREHVGKSKARVA 78
            |..::.||||::|...:|.||.|.|.|:|..::.::|...:|...:...||:..........:.|
Worm    30 QNKIRNSKVLIIGGKQLGAEVAKTLSLAGVDEMHLVDHRLVDTEEIGMNFLYDASVDNSKMTKWA 94

  Fly    79 RESALSFNPDAKITAY---HDSVTSTDYGV-NFFKKFDLVLSALDNRAARN-HVNRMCLNADVPL 138
            ......:|.:..:..:   .|.::..|..: .:..||.||: .||....|. .||.:|....:..
Worm    95 ASYNFLYNLNRNVKLFIVEEDVLSKNDSEIEEYLTKFTLVV-VLDESYERTAKVNNICRKHHIRF 158

  Fly   139 IES---GTAGY-----NGQVELIKRGLTQC 160
            |..   |..||     :|...|:|.....|
Worm   159 ISGAIYGWIGYAFFDFDGHAYLVKAKSPDC 188

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Uba2	NP_524756.2	ThiF	7..>177	CDD:279270	39/160 (24%)
		Uba2_SUMO	21..459	CDD:238766	37/153 (24%)
		UAE_UbL	467..552	CDD:291402
		UBA2_C	573..691	CDD:292812
aos-1	NP_505604.2	E1-1_like	17..345	CDD:238762	39/160 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0476
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810