Protein Alignment Uba2 and APP-BP1

DIOPT Version :10

• Sequence 1: NP_524756.2
• Gene: Uba2 / 44496
• FlyBaseID: FBgn0029113
• Length: 700
• Species: Drosophila melanogaster
• Sequence 2: XP_315544.3
• Gene: APP-BP1 / 1276227
• VectorBaseID: AGAMI1_005818
• Length: 523
• Species: Anopheles gambiae
• Alignment Length: 513
• Identity: 95/513 - (18%)
• Similarity: 169/513 - (32%)
• Gaps: 146/513 - (28%)

  Fly    14 QELVKKSKVLVVGAGGIGCEVLKNLVLSGFTDIEIIDLDTIDLSNLNRQFLFHREHVGKSKARVA 78
            |.:::.:::.::.|..:|.|:||.:||.|.....|:|...:...::...|....:.||:.:|:..
Mosquito    30 QTVLENAQICLINATALGTEILKGIVLPGIGGFTIVDHRPVTEEDVGCNFFLDLDSVGQPRAKRC 94

  Fly    79 RESALSFNPDAKITAYHDSVTS-TDYGVNFFKKFDLVLSALDNRAARNHVNRMCLNADVPLIESG 142
            .:.....|||.......:.|.. .|...:||:.||:|::...:......::.:..:.::|||.:.
Mosquito    95 MQLLQELNPDVNGDYVDEHVEQLIDGQPDFFRSFDVVVATSISERTIMRLSNVLWDQNIPLIVAR 159

  Fly   143 TAGYNGQVELIKRGLTQCYECTPKDKQRSFPGCTIRNTPSEPIHCIVWAKHLFNQLFGESLED-- 205
            :.|:.|...|..|.                             |||| ..|..|:.....||.
Mosquito   160 SVGFYGVARLQLRE-----------------------------HCIV-ETHPDNKQTDLRLEHPF 194

  Fly   206 EDISPDAADPDAKEK---------------DGGDGNG--------------EPKGDGKEKGEE-- 239
            |::....|:.....|               |..||..              ..|.||:::..|
Mosquito   195 EELKKHMAEAQITNKVPWLVVLYKVLQEWVDAHDGQYPASYREKTELRELIRSKMDGEQENFEEA 259

  Fly   240 ----------SKEEKEAKEDTANGNIMRINTRQ---WAKDCNYDAGKLFNKFFNEDITYLLRMSN 291
                      .|.....:|...:...:.:||..   |.      ..:....|.:.:...||
Mosquito   260 IKAVNSSFGGGKPSAAVREILQDDRCVNVNTESNAFWI------MARALKDFVDNEGNGLL---- 314

  Fly   292 LWKTRKAPVPVQWDTLLPEGSSGDQKDVAKQH-HKVWSIEECAQVFANS---LKELSANFLKLEG 352
                   |||    .:||:.::.....::.|. ::..:..:...||..:   ||||:.
Mosquito   315 -------PVP----GVLPDMTADTNSYISLQTVYRNQAAHDAEIVFRRARQLLKELNK------- 361

  Fly   353 DDTLAWDKDDQPAMDFVAACANVRSHIFDIERKSRFEIKSMAGNIIPAIATTNAITAGISVMRAF 417
            .:.|..|||.:......|..|.||......|....:...|   :|...:...|::.....|:||.
Mosquito   362 PNDLITDKDVRLFCREAANIAVVRGTKITDEFDKGYHRSS---HIASVLEQPNSLMGHYIVLRAL 423

  Fly   418 KVLEAKWEQCKAVYARLRPNARNHFLVPDASLPGPNPNCHVCASDPAITLKIDTKRMR 475
            ...:|.:                      ..|||        .|||    :.||..|:
Mosquito   424 DRFQADY----------------------GCLPG--------ESDP----ESDTTGMK 447

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Uba2	NP_524756.2	Uba2_SUMO	21..459	CDD:238766	88/488 (18%)
		UAE_UbL	467..552	CDD:464286	3/9 (33%)
APP-BP1	XP_315544.3	None