Protein Alignment GluRIB and GLR1.3

DIOPT Version :10

• Sequence 1: NP_001261621.2
• Gene: GluRIB / 44484
• FlyBaseID: FBgn0264000
• Length: 1182
• Species: Drosophila melanogaster
• Sequence 2: NP_199652.1
• Gene: GLR1.3 / 834896
• AraportID: AT5G48410
• Length: 860
• Species: Arabidopsis thaliana
• Alignment Length: 1081
• Identity: 191/1081 - (17%)
• Similarity: 349/1081 - (32%)
• Gaps: 369/1081 - (34%)

  Fly     2 RFGLKLSCLWPSFLLWL----------TWSSGGGGGSGVGVSAQPSLTEKIPLGAIFEQGT---- 52
            ||.::...|. ||||.|          |.:....||..|          :|.:|.:.:.|:
plant     3 RFCIQTQTLL-SFLLVLLLFISRSFASTKNDDVDGGKRV----------QIRVGLVLDLGSLKGK 56

  Fly    53 ---DEVQSAFKYAMLNHN-----LNVSSRRFELQAYVDVINTADAFKLSRLICNQFSRGVYSMLG 109
               :.|..|..|....||     ::||.|....:..:.:.:..|..|         :.||.:::|
plant    57 IVKNSVSMALSYFYAIHNDYKTRVSVSLRNSHGEPLLALASAVDLLK---------TEGVEAIIG 112

  Fly   110 AVSPDSFDTLHSYSNTFQMPFVTPWFPEKVLTPSSGFLD--FALSMRPDYH--QAIIDT------ 164
            ..|......|.......::|.::              ||  |:||:....|  ||..|:
plant   113 GNSLLEAKLLGELGEKARVPMIS--------------LDSPFSLSLSKYTHLIQATHDSTSEAKG 163

  Fly   165 ----IQFYGWRKIIYLYDSHDGLLRLQQIY------QGLR---------PGNESFQVELVKRISN 210
                |..:.|..:..:|:.||......|:.      .|:|         ..:|.|.:..::::.:
plant   164 ITSFINVFDWNSVALVYEDHDDWRESMQLLVEHFHENGVRVQSKVGFTVSSSEDFVMGRLQQLKD 228

  Fly   211 VSMAIEFLHTLEQIGRFENKHIVLDCPTEMAKQILIQHVRDLRLGRRTYHYLLSGLVMD------ 269
            :...:..:|..|.|...                 |....|.|.|....:.::|:...|:
plant   229 LGTTVFVVHLSEVIATH-----------------LFPCARRLGLMGDGFVWILTAKTMNSFHENI 276

  Fly   270 DRWESEIIEFGAINITGFRIVDTNRRLVREFYDSWKRLDPQMSVGAGRESISAQAALMYDAVFVL 334
            |.:..:.:|    .:.||:........::.|...|::..|.......|.|||...|  :|..|.|
plant   277 DDFTKQAME----GVVGFKSYIPMSIELQNFTLRWRKSLPVEEAELTRLSISGIWA--HDIAFAL 335

  Fly   335 VEAFNKILRKKPDQFRNNVQRRSQTLMVAQAAASTSSDGYNYSASGGGGGNGGAGGGFAGSDSGG 399
            ..|...|  :.|     ||   :.||:
plant   336 ARAAEVI--RMP-----NV---TSTLL-------------------------------------- 352

  Fly   400 SGGMASRALDCNTAKGWVNAWEHGDKISRYLRKVEIEGLTGDIKFNDDGRRVNYTLHVVEMTVNS 464
                                        ..:.|....||:||.:.||. :.::....::.| :.|
plant   353 ----------------------------EEITKTRFNGLSGDFQLNDK-KLLSNKFEIINM-IGS 387

  Fly   465 AMVKVAEWNDDAGLQPLNAKYVRLRPHVEFEKNRTYIV------------TTVLEEPYIMLKQVA 517
            :..:|...|.:.....        |.|:....|:...:            |::::.....|:.:
plant   388 SERRVGFLNSNGSFSN--------RRHLSSTHNKLETIIWPGGSAQSPKGTSLIDSDRKKLRVL- 443

  Fly   518 FGEKLHGNNRF-----------------EGYCKDLADLLAKELGINYELRLV---KDGNYGSEKS 562
                :..:|||                 ||:|.::  ..|.....|||:..:   ...||.:...
plant   444 ----VTSSNRFPRLMKVETDPVTNELIVEGFCIEV--FRASISPFNYEVEYIPWLNGSNYDNLAY 502

  Fly   563 SAHGGWDGMVGELVRKEADIAIAAMTITAERERVIDFSKPFMSLGISIMIKKPVKQTPGVFSFMN 627
            :.|...|         :.|.|:..:|||:.|...:||:.||..:|:.|:   .||:. .::.|..
plant   503 ALHSQKD---------KYDAAVGDITITSNRSTYVDFTLPFTEMGLGIV---AVKER-SMWVFFQ 554

  Fly   628 PLSQEIWVSVIFSYIGVSIVLFFVSRFSPHEWRLVQQQPQQSQSPDPHAHHEQLANQQPPGIIGG 692
            ||:.::|::..|.::...::::.:.|....|::  ...|||.                  |::
plant   555 PLTPDLWITSAFFFVLTGVIVWLIERAENKEFQ--GSWPQQI------------------GVV-- 597

  Fly   693 APLPAPPGPPTPGAQTAAGAAALQAALSAGSPGSGGSSSAVVNEFSVWNSFWFSLAAFMQQGCDL 757
                                                              .||..:..:....:.
plant   598 --------------------------------------------------LWFGFSTLVYAHREK 612

  Fly   758 SPRSVSGRIAAASWFFFTLILISSYTANLAAFLTVERMVTPINSPEDLAMQTEVQYGTLLHGSTW 822
            ...::| |.....|.|..|||.:||||.|.:.:||:::  ..||.||        |...|.||.
plant   613 LKHNLS-RFVVTVWVFAVLILTASYTATLTSMMTVQQI--RFNSNED--------YVGHLSGSL- 665

  Fly   823 DFFRRSQIGLHNKMWEYMNSRKHVFVPTYDEGIKRVRNSKGKYA----------LLVESPKNEYV 877
                .:.:.|.:.....|.|.          |:    ||...||          ::.|.|..:.|
plant   666 ----IANVALTSSSLRAMRSL----------GL----NSAADYAQALLNKTVSFVVDELPYLKVV 712

  Fly   878 NAREPCDTMKVGRNLDTKGFGIATPLGSALKDPINLAVLTLKENGELIKLRNKWWYEKAECSTHK 942
            ....|.....|.....|.|||.....|..|...::..:..|:.:.:|.::..:|:..:...:|
plant   713 LGENPTHFFMVKTQSTTNGFGFMFQKGFELVPNVSREISKLRTSEKLNEMEKRWFDNQLPYTT-- 775

  Fly   943 DGETSHSELSLSNVAGIFYILIGGLLVSVFVAILEYCFRSR 983
              :.:.:.::|....|:| |:||.........::..|.|.:
plant   776 --DDTSNPITLYRFRGLF-IIIGVSFAFALAVLVILCLRDK 813

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluRIB	NP_001261621.2	PBP1_iGluR_AMPA	43..480	CDD:380603	79/483 (16%)
		PBP2_iGluR_AMPA	497..938	CDD:270433	88/482 (18%)
		Lig_chan	630..966	CDD:459656	60/345 (17%)
GLR1.3	NP_199652.1	PBP1_GABAb_receptor_plant	43..405	CDD:380645	79/493 (16%)
		GluR_Plant	438..767	CDD:270404	85/450 (19%)