Protein Alignment GluRIB and GLR2.6

DIOPT Version :9

• Sequence 1: NP_001261621.2
• Gene: GluRIB / 44484
• FlyBaseID: FBgn0264000
• Length: 1182
• Species: Drosophila melanogaster
• Sequence 2: NP_001330285.1
• Gene: GLR2.6 / 830988
• AraportID: AT5G11180
• Length: 967
• Species: Arabidopsis thaliana
• Alignment Length: 1119
• Identity: 227/1119 - (20%)
• Similarity: 389/1119 - (34%)
• Gaps: 367/1119 - (32%)

  Fly    30 VGVSAQPSLTEKIPLGAIFEQGTDEVQSAFKYAMLNHNLNVSSRRFELQAYVDVINTADAFKLSR 94
            :|.|.|..|  ::.:|.:.:  |:...:|.....:|.:|:            :..||.:.|| :|
plant    26 LGKSQQEVL--QVQVGIVLD--TNATLAALSLRAINMSLS------------EFYNTHNGFK-TR 73

  Fly    95 LICN------------------QFSRGVYSMLGAVSPDSFDTLHSYSNTFQMPFVTPWFPEKVLT 141
            ::.|                  ...|.|.:::|..:......|.:..|..|:|.::       .:
plant    74 IVLNIRDSKRTVVGAAASALYLIKKREVVAIIGPGNSMQAPFLINLGNQSQVPIIS-------FS 131

  Fly   142 PSSGFLDFALSMRPDYH-----------QAIIDTIQFYGWRKIIYLYDSH---DGLL-----RLQ 187
            .||..||   |:|..|.           .||...|:.:.||:::.:|..:   :|:|     ..|
plant   132 ASSPVLD---SLRSPYFIRATHDDSSQVHAISAIIESFRWREVVPIYADNEFGEGILPYLVDAFQ 193

  Fly   188 QIYQGLRPGNESFQV----ELVK----RISNVSMAIEFLHTLEQIGR----------FENKHIVL 234
            :|...:| ...:..|    :|||    ::..:...:..:|.|..:|.          ...|..|.
plant   194 EINVRIR-YRSAISVHSTDDLVKKELYKLMTMPTRVFIVHMLPDLGSRLFSIAKEIGMMTKGYVW 257

  Fly   235 DCPTEMAKQILIQHVRDLR-----LGRRTYHYLLSGLV-MDDRWESEIIEFGAINITGFRIVDTN 293
            .....:|.|:.:.....|.     ||.:||......|: ::.||..   .||...:..|
plant   258 IVTNGIADQMSVMGESSLENMHGVLGVKTYFSRSKELMYLETRWRK---RFGGEELNNF------ 313

  Fly   294 RRLVREFYDSWKRLDPQMSVGAGRESISAQAALMYDAVFVLVEAFNKILRKKPDQFRNNVQRRSQ 358
                    :.| ..|...::....|.||:...:.:                  .|.:.|..|..
plant   314 --------ECW-GYDTATALAMSIEEISSNVNMSF------------------SQTKRNTSRDD- 350

  Fly   359 TLMVAQAAASTSSDGYNYSASGGGGGNGGAGGGFAGSDSGGSGGMASRALDCNTAKGWVNAWEHG 423
                    ..|..|..:::.||.......|...|.|  ..|...:.:..|:..|.| .||..|.|
plant   351 --------TGTDLDDLSFALSGPKLLQALATVSFKG--VAGRFQLKNGKLEATTFK-IVNIEESG 404

  Fly   424 DK-ISRYLRKVEIEGLTGDIKFNDDGRRVNYTLHVVEMTVNSAMVKVAEWNDDA-----GLQ-PL 481
            :: :..:..||   ||...::.|..|.:::::.|.:...:         |..|.     |.: |.
plant   405 ERTVGFWKSKV---GLVKSLRVNQTGIKISHSSHRLRPII---------WPGDTIFVPKGWEFPT 457

  Fly   482 NAKYVRL--------RPHVEFEKNRTYIVTTVLEEPYIMLKQVAFGEKLHGNNRFEGYCKDLADL 538
            |||.:|:        ...||..|:......|:                       .|:|.|:.|.
plant   458 NAKKLRIAVPKKDGFNNFVEVTKDANTNAPTI-----------------------TGFCIDVFDT 499

  Fly   539 LAKEL--GINYELRLVKDGNYGSEKSSAHGGWDGMVGELVRKEADIAIAAMTITAERERVIDFSK 601
            ..:::  .:.||..     .:.:......|.:|.||..:...|.|.|:...||.|.|...:||:.
plant   500 AMRQMPYAVPYEYI-----PFETPDGKPRGSYDEMVYHVFLGEFDGAVGDTTILANRSTYVDFAL 559

  Fly   602 PFMSLGISIMIKKPVK--QTPGVFSFMNPLSQEIW--VSVIFSYIGVSIVLFFVSRFSPHEWRLV 662
            |:...||.:::  |||  :..|.:.|:.||::|:|  .:..|.|||:.:.:|        |::
plant   560 PYSETGIVVVV--PVKDEREKGKWVFLKPLTRELWFLTAASFLYIGIMVWIF--------EYQ-- 612

  Fly   663 QQQPQQSQSPDPHAHHEQLANQQPPGIIGGAPLPAPPGPPTPGAQTAAGAAALQAALSAGSPGSG 727
                                                          |:|....|
plant   613 ----------------------------------------------ASGDFRKQ----------- 620

  Fly   728 GSSSAVVNEFSVWNSFWFSLA----AFMQQGCDLSPRSVSGRIAAASWFFFTLILISSYTANLAA 788
                :::|:.|  |.|:||.:    |.|:..     .|:..|:....|.|..|||..||||.|.:
plant   621 ----SIINKIS--NVFYFSFSTLFFAHMRPS-----ESIFTRVLVVVWCFVLLILTQSYTATLTS 674

  Fly   789 FLTVERMVTPINSPEDLAMQ-TEVQYGTLLHGSTWDFFRRSQIGLHNKMWEYMNSRKHVFVPTYD 852
            .|||:.:...:...:||... ..:.|.|    .::.|.|..|:|       |..||    :.|||
plant   675 MLTVQELRPTVRHMDDLRNSGVNIGYQT----GSFTFERLKQMG-------YKESR----LKTYD 724

  Fly   853 EGIKRVRNSKGKYALLVESPKNEYVNAR---------------------EPCDTMKVGRNLDTKG 896
                   ..:..:.|.::...|..::|.                     ||  |.|      ..|
plant   725 -------TPQEMHELFLKKSSNGGIDAAFDEVAYVKLFMAKYCSKYTIIEP--TFK------ADG 774

  Fly   897 FGIATPLGSALKDPINLAVLTLKENGELIK-LRNKWWYEKAECSTHKDGETSHSELSLSN----- 955
            ||.|.||||.|...::..:|.:.| ||.:| :.|||...:..|   .|..||.|.:.|.:
plant   775 FGFAFPLGSPLVPDLSRQILNITE-GETMKAIENKWLLGEKHC---LDSTTSDSPIRLDHHSFEA 835

  Fly   956 VAGIFYILIGGLLVSVFVAILEYCFRSR-DSRSASSGSGMGLGMGLGGGMSGGSLGKANGSMMLG 1019
            :..|.:::...||:::.|     |.|.| :|:|               |....:....:|:|...
plant   836 LFTIVFVVSMLLLLAMLV-----CRRYRQESKS---------------GEINANNSPTDGNMRAP 880

  Fly  1020 PSSAVPGGM--PSS 1031
            |:......|  |:|
plant   881 PNQPTDDNMRAPTS 894

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluRIB	NP_001261621.2	PBP1_iGluR_AMPA	43..478	CDD:107375	90/501 (18%)
		ANF_receptor	55..461	CDD:279440	86/467 (18%)
		PBP2_iGluR_AMPA	497..938	CDD:270433	102/473 (22%)
		Lig_chan	632..967	CDD:278489	79/368 (21%)
GLR2.6	NP_001330285.1	PBP1_GABAb_receptor_plant	38..421	CDD:380645	85/459 (19%)
		GluR_Plant	460..810	CDD:270404	106/488 (22%)
		Lig_chan	590..842	CDD:365843	79/363 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	82	0.746	Domainoid score	I2907
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG60082
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000021
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18966
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.010