Protein Alignment GluRIB and GLR2.3

DIOPT Version :9

• Sequence 1: NP_001261621.2
• Gene: GluRIB / 44484
• FlyBaseID: FBgn0264000
• Length: 1182
• Species: Drosophila melanogaster
• Sequence 2: NP_001325281.1
• Gene: GLR2.3 / 817007
• AraportID: AT2G24710
• Length: 919
• Species: Arabidopsis thaliana
• Alignment Length: 1078
• Identity: 217/1078 - (20%)
• Similarity: 375/1078 - (34%)
• Gaps: 325/1078 - (30%)

  Fly     9 CLWPSFLLWLTWSSGGGGGSGVGVSAQPSLTEKIPLGAIFEQGTDEVQSAFKYAMLNHNLNV--- 70
            |:...|...|.::.|...|..:           :.:|.:    ||...|..|..||..|:::
plant    33 CILLVFFFCLEFNRGQNNGKTL-----------VDVGVV----TDVDTSHSKVVMLCINMSISDF 82

  Fly    71 --SSRRFELQAYV-------DVINTA----DAFKLSRLICNQFSRGVYSMLGAVSPDSFDTLHSY 122
              |:.:||.:..|       ||:..|    |..|         ::.|.::||..:......|...
plant    83 YSSNPQFETRLVVNVGDSKSDVVGAAIAALDLIK---------NKQVKAILGPWTSMQAHFLIEI 138

  Fly   123 SNTFQMPFVTPWFPEKVLTPSSGFLDFALSMRPDYH-----------QAIIDTIQFYGWRKIIYL 176
            ....::|.|:......:||          |:|..|.           |.|...|:.:|||:::.:
plant   139 GQKSRVPIVSYSATSPILT----------SLRSPYFLRATYEDSFQVQPIKAIIKLFGWREVVPV 193

  Fly   177 YDSH---DGLL-RLQQIYQGLR---PGNESFQVELVKRISNVSMAIEFLHTLEQIGRFENKHIVL 234
            |..:   :|:: ||....|.:.   |    ::..:....::..:::|.|..:....|....|:..
plant   194 YIDNTFGEGIMPRLTDALQDINVRIP----YRSVIAINATDHEISVELLKMMNMPTRVFLVHMYY 254

  Fly   235 DCPTEMAKQILIQHVRDLRLGRRTYHYLLSGLVMDDRWESEIIEFGAI----NITGFRIVDTNRR 295
            |    :|.:..|: .::|.|....|.::|:..|:||   ..:|...|:    .:.|.:.......
plant   255 D----LASRFFIK-AKELGLMEPGYVWILTNGVIDD---LSLINETAVEAMEGVLGIKTYIPKSP 311

  Fly   296 LVREFYDSWKRLDPQMSVGAGRESISAQAALMYDAVFVLVEAF------NKILRKKPDQFRNNVQ 354
            .:.:|...|:.|.|       |..:|......|||...|..|.      |....|..|..||..:
plant   312 DLEKFRSRWRSLFP-------RVELSVYGLWAYDATTALAVAIEEAGTNNMTFSKVVDTGRNVSE 369

  Fly   355 RRS-----------QTLMVAQAAASTSSDGYNYSASGGGGGNGGAGGGFAGSDSGGSGGMASRAL 408
            ..:           |||:..|..                        |.||......|.:.....
plant   370 LEALGLSQFGPKLLQTLLTVQFR------------------------GLAGEFRFFRGQLQPSVF 410

  Fly   409 D----CNTAKGWVNAWEHGDKISRYLRKVEIEGLTGDIKFNDDGRRVNYTLHVVEMTVNSAMVKV 469
            :    .||.:..:..|:.|:.:.:.|.: :...::....:.|      :..|:|
plant   411 EIVNIINTGEKSIGFWKEGNGLVKKLDQ-QASSISALSTWKD------HLKHIV----------- 457

  Fly   470 AEWNDDAGLQP----LNAKYVRLRPHVEFEKNRTYIVTTVLEEPYIMLKQVAFGEKLHGNNRFEG 530
              |..:|...|    :..|..:||..|......|.:| .|..:|            :..:....|
plant   458 --WPGEADSVPKGWQIPTKGKKLRIGVPKRTGYTDLV-KVTRDP------------ITNSTVVTG 507

  Fly   531 YCKDLADLLAKEL--GINYELRLVKD------GNYGSEKSSAH-GGWDGMVGELVRKEADIAIAA 586
            :|.|..:.:.:||  .::||....:.      |||.......: |.:|.:||:
plant   508 FCIDFFEAVIRELPYDVSYEFIPFEKPDGKTAGNYNDLVYQVYLGRYDAVVGD------------ 560

  Fly   587 MTITAERERVIDFSKPFMSLGISIMIK--KPVKQTPGVFSFMNPLSQEIWVSVIFSY--IGVSIV 647
            .||...|...:||:.||:..|:.::::  .|||:  ....||.|||.::|::...|:  :|.::
plant   561 TTILVNRSSYVDFTFPFIKSGVGLIVEMTDPVKR--DYILFMKPLSWKLWLTSFISFFLVGCTV- 622

  Fly   648 LFFVSRFSPHEWRLVQQQPQQSQSPDPHAHHEQLANQQPPGIIGGAPLPAPPGPPTPGAQTAAGA 712
                       |.|     :..::||                        ..|||...|.|..
plant   623 -----------WVL-----EYKRNPD------------------------FSGPPRFQASTIC-- 645

  Fly   713 AALQAALSAGSPGSGGSSSAVVNEFSVWNSFWFSLAAFMQQGCDLSPR----SVSGRIAAASWFF 773
                                           ||:.:..:     .:||    |...|....:|:|
plant   646 -------------------------------WFAFSTMV-----FAPRERVFSFWARALVIAWYF 674

  Fly   774 FTLILISSYTANLAAFLTVERMVTPINSPEDLAMQTEVQYGTLLHGSTWDFFRRSQIGLHNKMWE 838
            ..|:|..||||:||:.||.:::...|.|...|          |..|.|..:.|.|.|....|...
plant   675 LVLVLTQSYTASLASLLTSQKLNPTITSMSSL----------LEKGETVGYQRTSFILGKLKERG 729

  Fly   839 YMNSRKHVFVP-----TYDEGIKRVRNSKGKYALLVESPK---------NEYVNAREPCDTMKVG 889
            :..|.   .||     ..||.:.:.....|.....:|.|.         |.|....||.
plant   730 FPQSS---LVPFDTAEECDELLSKGPKKGGVSGAFLEIPYLRLFLGQFCNTYKMVEEPF------ 785

  Fly   890 RNLDTKGFGIATPLGSALKDPINLAVLTLKENGELIKLRNKWWYEKAE-CS---THKDGETSHSE 950
             |:|  |||...|:||.|...::.|:|.:.|:.:.::|...|:.:|.: |.   |:.|...|.:.
plant   786 -NVD--GFGFVFPIGSPLVADVSRAILKVAESPKAMELERAWFKKKEQSCPDPITNPDPNPSFTS 847

  Fly   951 LSLSNVAGIFYILIGGLLVSVF-VAILEYCFRSRDSRS 987
            ..| ::....::.:|.|||.|. :....|||.::|..|
plant   848 RQL-DIDSFLFLFVGVLLVCVMALGNFTYCFLAKDQVS 884

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluRIB	NP_001261621.2	PBP1_iGluR_AMPA	43..478	CDD:107375	91/493 (18%)
		ANF_receptor	55..461	CDD:279440	86/464 (19%)
		PBP2_iGluR_AMPA	497..938	CDD:270433	101/472 (21%)
		Lig_chan	632..967	CDD:278489	73/358 (20%)
GLR2.3	NP_001325281.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	82	0.746	Domainoid score	I2907
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG60082
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000021
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18966
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.920