Protein Alignment GluRIB and Grik

DIOPT Version :9

• Sequence 1: NP_001261621.2
• Gene: GluRIB / 44484
• FlyBaseID: FBgn0264000
• Length: 1182
• Species: Drosophila melanogaster
• Sequence 2: NP_001262788.1
• Gene: Grik / 42476
• FlyBaseID: FBgn0038840
• Length: 907
• Species: Drosophila melanogaster
• Alignment Length: 981
• Identity: 286/981 - (29%)
• Similarity: 445/981 - (45%)
• Gaps: 228/981 - (23%)

  Fly    40 EKIPLGAIFEQGTDEVQSAFKYAMLNHNLNVSSRRFELQAYVDVINTADAFKLSRLICNQFSRGV 104
            |:..:|.::|....:::..|..|:  ...|..:...:|......|...::|:.|:.:|....:.:
  Fly    32 ERTNVGLVYENTDPDLEKIFHLAI--SKANEENEDLQLHGVSVSIEPGNSFETSKKLCKMLRQNL 94

  Fly   105 YSMLGAVSPDSFDTLHSYSNTFQMPFV-TPW-----FPEKVLTPSSGFLDFALSMRPDYHQAIID 163
            .::.|..|..:.....|..:..::||: |.|     .|...|.|....|..||.          |
  Fly    95 VAVFGPTSNLAARHAMSICDAKELPFLDTRWDFGAQLPTINLHPHPATLGVALR----------D 149

  Fly   164 TIQFYGWRKIIYLYDSHDGLLRLQQIYQ-----GLRPGNESFQVEL-------VKRISNV----- 211
            .:...||.....:|:|.:.|..::::.|     |.......::::|       ::||.|.
  Fly   150 MVVALGWESFTIIYESGEYLPTVRELLQMYGTAGPTVTVRRYELDLNGNYRNVLRRIRNADDFSF 214

  Fly   212 ----SMAI--EFLHTLEQIGRFENKHIVLDCPTEMAKQILIQHVRDLRLGRRTYHYLLSGLVMDD 270
                |||.  ||....:|:|                            |....|.|::..|
  Fly   215 VVVGSMATLPEFFKQAQQVG----------------------------LVTSDYRYIIGNL---- 247

  Fly   271 RWES---EIIEFGAINITGFRIVDTNRRLVRE----FYDSWKRLDPQMSVGAGRESISAQAALMY 328
            .|.:   |..:....||||.|:|..:...|:|    .|:|   .:|..:|..   .::...||:|
  Fly   248 DWHTMDLEPYQHAGTNITGLRLVSPDSEQVQEVAKALYES---EEPFQNVSC---PLTNSMALVY 306

  Fly   329 DAVFVLVEAFNKILRKKPDQFRNNVQRRSQTLMVAQAAASTSSDGYNYSASGGGGGNGGAGGGFA 393
            |.|.:|.|.:..:      .||
  Fly   307 DGVQLLAETYKHV------NFR------------------------------------------- 322

  Fly   394 GSDSGGSGGMASRALDCNTAKGWVNAWEHGDKISRYLRKVEIEGLTGDIKFNDDGRRVNYTLHVV 458
                       ..||.||..    :||:.|..:..|::.:.:.||||.|:|:.:|.|.::.|.|:
  Fly   323 -----------PVALSCNDD----SAWDKGYTLVNYMKSLTLNGLTGPIRFDYEGLRTDFKLEVI 372

  Fly   459 EMTVNSAMVKVAEWNDDAGLQ---PLNAKYVRLRPHVEFEKNRTYIVTTVLEEPYIMLKQVAFGE 520
            |:.| |.|.|:.:|:.:.|.|   |..|.  .|.|.:....|::::|.|.:.|||.|||:.:  |
  Fly   373 ELAV-SGMQKIGQWSGEDGFQENRPAPAH--SLEPDMRSLVNKSFVVITAISEPYGMLKETS--E 432

  Fly   521 KLHGNNRFEGYCKDLADLLAKELGINYELRLVKDGNYGSEKSSAHGGWDGMVGELVRKEADIAIA 585
            ||.||::|||:..:|.|.|:|:||.:|..||.:|..||...... |.|:||:.|::...||:.|.
  Fly   433 KLEGNDQFEGFGIELIDELSKKLGFSYTWRLQEDNKYGGIDPKT-GEWNGMLREIIDSRADMGIT 496

  Fly   586 AMTITAERERVIDFSKPFMSLGISIMIKKPVKQTPGVFSFMNPLSQEIWVSVIFSYIGVSIVLFF 650
            .:|:|:|||..:||:.|||||||.|:.:||:|:.|.:||||:|.|.|:|:.:..:|:||||.:|.
  Fly   497 DLTMTSERESGVDFTIPFMSLGIGILFRKPMKEPPKLFSFMSPFSGEVWLWLGLAYMGVSISMFV 561

  Fly   651 VSRFSPHEWRLVQQQPQQSQSPDPHAHHEQLANQQPPGIIGGAPLPAPPGPPTPGAQTAAGAAAL 715
            :.|.||.||                                ..|.|....|
  Fly   562 LGRLSPAEW--------------------------------DNPYPCIEEP-------------- 580

  Fly   716 QAALSAGSPGSGGSSSAVVNEFSVWNSFWFSLAAFMQQGCDLSPRSVSGRIAAASWFFFTLILIS 780
                           :.:.|:||..|..|||:.|.:|||.:|:|::.|.|..||||:||||||:|
  Fly   581 ---------------TELENQFSFANCLWFSIGALLQQGSELAPKAYSTRAVAASWWFFTLILVS 630

  Fly   781 SYTANLAAFLTVERMVTPINSPEDLAM-QTEVQYGTLLHGSTWDFFRRSQIGLHNKMWEYMNSRK 844
            |||||||||||||.:|||||..:||:. :..|.||..:.|:|::||:.|....:.:|:|:|....
  Fly   631 SYTANLAAFLTVESLVTPINDADDLSKNKGGVNYGAKIGGATFNFFKESNYPTYQRMYEFMRDNP 695

  Fly   845 HVFVPTYDEGIKRVRNSKGKYALLVESPKNEYVNAREPCDTMKVGRNLDTKGFGIATPLGSALKD 909
            .....|..||:.||.||  .||.|:||...||:..|. |...:||..||.||:|||.......:|
  Fly   696 QYMTNTNQEGVDRVENS--NYAFLMESTTIEYITERR-CTLTQVGALLDEKGYGIAMRKNWPYRD 757

  Fly   910 PINLAVLTLKENGELIKLRNKWWYEK---AECSTHKDGETSHSELSLSNVAGIFYILIGGLLVSV 971
            .::.|||.::|.|.|.|::.|||.||   ..|| ..|.::....|.:||:.|:|.::..|....:
  Fly   758 TLSQAVLEMQEQGLLTKMKTKWWQEKRGGGACS-DADEDSGAVALEISNLGGVFLVMGVGSFFGI 821

  Fly   972 FVAILE 977
            ||::||
  Fly   822 FVSLLE 827

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluRIB	NP_001261621.2	PBP1_iGluR_AMPA	43..478	CDD:107375	93/470 (20%)
		ANF_receptor	55..461	CDD:279440	86/441 (20%)
		PBP2_iGluR_AMPA	497..938	CDD:270433	173/444 (39%)
		Lig_chan	632..967	CDD:278489	119/338 (35%)
Grik	NP_001262788.1	PBP1_iGluR_Kainate	37..391	CDD:107377	93/468 (20%)
		ANF_receptor	53..374	CDD:279440	84/434 (19%)
		Periplasmic_Binding_Protein_Type_2	411..781	CDD:304360	170/436 (39%)
		Lig_chan	543..816	CDD:278489	119/337 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462524
Domainoid	1	1.000	82	0.746	Domainoid score	I2907
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000021
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100167
Panther	1	1.100	-	-	P	PTHR18966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.840