Protein Alignment GluRIB and Ir64a

DIOPT Version :10

• Sequence 1: NP_001261621.2
• Gene: GluRIB / 44484
• FlyBaseID: FBgn0264000
• Length: 1182
• Species: Drosophila melanogaster
• Sequence 2: NP_647962.1
• Gene: Ir64a / 38616
• FlyBaseID: FBgn0035604
• Length: 859
• Species: Drosophila melanogaster
• Alignment Length: 631
• Identity: 121/631 - (19%)
• Similarity: 211/631 - (33%)
• Gaps: 144/631 - (22%)

  Fly   451 VNYTLHVVEMTVNSAMVKVAEWNDDAGLQPLNAKY-----VRLRPHVEFEKNRTYIVTTVLEEPY 510
            :||..||       .:.::..:....|:| |:..:     ||.|..::..:.|..:|.|......
  Fly   269 LNYGGHV-------NLTEIGSFTPTEGIQ-LHTWFRTTSTVRRRMDMQHARVRCMVVVTNKNMTG 325

  Fly   511 IMLKQVAFGEKLHGN--NRFEGYCKDLADLLAKELGINYELRLVKDGNYGSEKSSAHGGWDGMVG 573
            .::..:......|.:  |||     :...|:|.....|:...|.:..::|..|   :|.:|||:|
  Fly   326 TLMYYLTHTMSGHIDTMNRF-----NFNLLMAVRDMFNWTFVLSRTTSWGYVK---NGRFDGMIG 382

  Fly   574 ELVRKEADIAIAAMTITAERERVIDFSKPFMSLGISIMIKKPVKQTPGVFSFMNPLSQEIWVSVI 638
            .|:|.|.||..|.:....||.:.||.:....|.....:.:.|.........|:.|.:.::|:.::
  Fly   383 ALIRNETDIGGAPIFYWLERHKWIDVAGRSWSSRPCFIFRHPRSTQKDRIVFLQPFTNDVWILIV 447

  Fly   639 FSYIGVSIVLFFVSRFSPHEWRLVQQQPQQSQSPD---PHAHHEQLANQQPPGIIGGAPLPAPPG 700
            ...:....:|:|::..   ||:||.........|.   |..||.|...||       ..:.||..
  Fly   448 GCGVLTVFILWFLTTI---EWKLVPHDGSALIKPKGGAPPRHHYQQQQQQ-------EQVEAPVR 502

  Fly   701 PPTPGAQTAAGAAALQAALS---AGSPGSGGSSSAVVNEFSVW---------------------- 740
            |.|          |:...:|   ..........|..::..::|
  Fly   503 PIT----------AVSVVVSKEKVEEKQEEYEDSTPIDAGTLWQRCYQKLNKYIKDRKAKQKKAP 557

  Fly   741 -------NSFWFSLAAFMQQGCDLSPRSVSGRIAAASWFFFTLILISSYTANLAAFLTVERMVTP 798
                   .|..|.:....|||...|...||||....:...|:..:...|:|::...|.:|:
  Fly   558 ERVGLFLESVLFFVGIICQQGLGFSTSFVSGRCIVITSLLFSFCIYQFYSASIVGTLLMEK---- 618

  Fly   799 INSPEDLAMQTEVQYGTLLHGSTWDFFRRSQIGLHNK----MWEYMNSRKHVFVPTYDEG----- 854
               |:.:...:::.:.:|..|.....:.|... ||.|    |..|  ::|...|||..|.
  Fly   619 ---PKTIKTLSDLVHSSLKVGMEDILYNRDYF-LHTKDPVSMELY--AKKITSVPTTKENEADED 677

  Fly   855 ------------IKRVRNSKGKYALLVESPKNEYVNAREP------------------------- 882
                        .|..|:....:.....:..|...|..:|
  Fly   678 EPVDPNPVSTDPAKSYRDIVHSHETGAHAKDNAASNWLDPETGLLRHLGFAFHVDVAAAYKIIAE 742

  Fly   883 -------CDTMKVGRNLDTKGFGIATPLGSALKDPINLAVLTLKENGELIKLRNKWWYEKAECST 940
                   ||..:|......|...|... .|.::..|:..:..:.|.|.|....|.|...|..|.
  Fly   743 TFSEQDICDLTEVSMFPPQKTVSIMQK-NSPMRKVISYGLRRVTETGILTYHFNVWHSRKPPCV- 805

  Fly   941 HKDGETSHSELSLSNVAGIFYILIGGLLVSVFVAILEYCFRSRDSR 986
             |..|||...:.:..|:....||:....:::.:...|..:....:|
  Fly   806 -KKIETSDLHVDMDTVSSALLILLFSYAITLMILGTEILYSKWHNR 850

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluRIB	NP_001261621.2	PBP1_iGluR_AMPA	43..480	CDD:380603	5/28 (18%)
		PBP2_iGluR_AMPA	497..938	CDD:270433	101/530 (19%)
		Lig_chan	630..966	CDD:459656	77/423 (18%)
Ir64a	NP_647962.1	Periplasmic_Binding_Protein_Type_2	351..>465	CDD:473866	27/119 (23%)
		Lig_chan	563..828	CDD:459656	54/277 (19%)