Protein Alignment GluRIB and Ir8a

DIOPT Version :9

• Sequence 1: NP_001261621.2
• Gene: GluRIB / 44484
• FlyBaseID: FBgn0264000
• Length: 1182
• Species: Drosophila melanogaster
• Sequence 2: NP_727328.1
• Gene: Ir8a / 31867
• FlyBaseID: FBgn0052704
• Length: 936
• Species: Drosophila melanogaster
• Alignment Length: 1003
• Identity: 222/1003 - (22%)
• Similarity: 401/1003 - (39%)
• Gaps: 277/1003 - (27%)

  Fly   140 LTPSSGFLDFALSMRPDYHQAIIDTIQFYGWRKIIYLYDSH------------DGLLRLQQIYQG 192
            ||.|...||.         |...:.:...|...:|.|..||            .|.:||::|
  Fly    61 LTRSEDGLDM---------QRFCEILSTVGASAVIDLTYSHWEEGYNLVRSLGIGYVRLERI--- 113

  Fly   193 LRPGNESF-QVELVKRISNVSM----AIEFLHTLEQ--IGRFENKHIVLDCPTEMAKQILIQHVR 250
            :||..:.| .....||.:||:|    |.:.:..::|  :| :..:.:::|.......|..::.:|
  Fly   114 MRPFLDMFGDFMRQKRANNVAMVFMNARDAVEAMQQMLVG-YPFRTLIMDASQTDPGQHFLERIR 177

  Fly   251 DLRLGRRTYHYLLS-GLVMDDRWE--------SEIIEFGAINITGFRIVDTNRRLVREFYDSWKR 306
            .|| ...||..|.: ...|:..:|        ...:|:      .|..:||..|:.:     ::|
  Fly   178 SLR-PAPTYIALFARAAAMNGIFEKVQKADLFQRPLEW------HFVFLDTRDRVFK-----YRR 230

  Fly   307 ---------LDPQ----------MSVGAGRESISAQAALMYDAVFVLVEAFNKILRKKPDQFRNN 352
                     |:|:          :..|:|   .:.|.|::.:.:..|:.|    .:..|......
  Fly   231 QAELCTRFTLNPRAICRSMPMPDLYCGSG---FTMQRAMLLNVLRSLINA----AQVSPGYPLAI 288

  Fly   353 VQRRSQTLMVAQAAASTSSDGYNYSASGGGGGNGGAGGGFAGSDSGGSGGMASRALDCNTAKGWV 417
            .|..:.|...::.:.....|.||:                               ||   ...|.
  Fly   289 YQDCNATASSSEVSDPLEKDDYNW-------------------------------LD---MVHWS 319

  Fly   418 NAWEHGDKISRYLRKVE--IEGLTGDIKFNDDGRRVNYTLHVVEMTVNSAMVKVAEWNDDAGLQP 480
            |...:...:.....:.:  :.|||..:..:     ..|     ..:.:.|...:|.|:....::.
  Fly   320 NFLAYAPPLPHIQDQFQSPVPGLTFAVNIS-----AGY-----YSSEHEAKTDLAAWSSVGEMRL 374

  Fly   481 LNAKYVRLRPHVEFEKNRTYIVTTVLEEPYIML-KQVAFGEKLH---GNNRFEGYCKDLADLLAK 541
            ||......|        |.:.:.|....|:..| ::...||.:.   |...:||||.|....|::
  Fly   375 LNETISPAR--------RFFRIGTAESIPWSYLRREEGTGELIRDRSGLPIWEGYCIDFIIRLSQ 431

  Fly   542 ELGINYELRLVKDGNYGSEKSSAHGGWDGMVGELVRKEADIAIAAMTITAERERVIDFSKPFM-S 605
            :|...:|:...:.|:.|  :.:..|.|||:||:|||.|.|.||||:.:.:|||.||||..|:. .
  Fly   432 KLNFEFEIVAPEVGHMG--ELNELGEWDGVVGDLVRGETDFAIAALKMYSEREEVIDFLPPYYEQ 494

  Fly   606 LGISIMIKKPVKQTPGVFSFMNPLSQEIWVSVIFSYIGVSIVLFFVSRFSPHEWRLVQQQPQQSQ 670
            .||||.|:|||::| .:|.||..|..|:|:|::.:.:|.:|:::|:.::||:..|       .::
  Fly   495 TGISIAIRKPVRRT-SLFKFMTVLRLEVWLSIVAALVGTAIMIWFMDKYSPYSSR-------NNR 551

  Fly   671 SPDPHAHHEQLANQQPPGIIGGAPLPAPPGPPTPGAQTAAGAAALQAALSAGSPGSGGSSSAVVN 735
            ...|:|                                                         ..
  Fly   552 QAYPYA---------------------------------------------------------CR 559

  Fly   736 EFSVWNSFWFSLAAFMQQGCDLSPRSVSGRIAAASWFFFTLILISSYTANLAAFLTVERMVTPIN 800
            ||::..||||:|.:|..||...:|:::|||:..|:::.|.:::::::|||||||||||||.||:.
  Fly   560 EFTLRESFWFALTSFTPQGGGEAPKAISGRMLVAAYWLFVVLMLATFTANLAAFLTVERMQTPVQ 624

  Fly   801 SPEDLAMQTEVQYGTLLHGSTWDFFRR------------SQIGLHN-------KMWEYMNSRK-- 844
            |.|.||.|:.:.|..:....|..:|..            .::.|:.       ::|:|....:
  Fly   625 SLEQLARQSRINYTVVKDSDTHQYFVNMKFAEDTLYRMWKELALNASKDFKKFRIWDYPIKEQYG 689

  Fly   845 HVFV------PTYD--EGIKRV-RNSKGKYALLVESPKNEYVNAREPCDTMKVGRNLDTKGFGIA 900
            |:.:      |..|  ||...| .:....||.:.:|.:.:|...|. |:..:||.....:.:.:|
  Fly   690 HILLAINSSQPVADAKEGFANVDAHENADYAFIHDSAEIKYEITRN-CNLTEVGEVFAEQPYAVA 753

  Fly   901 TPLGSALKDPINLAVLTLKENGELIKLRNKWWYEK--AECSTHKDGETSHSELSLSNVAGIFYIL 963
            ...||.|.|.::.|:|.|:::....:|:.|:|.:.  ..|...:|.|    .::|.::.|:|...
  Fly   754 VQQGSHLGDELSYAILELQKDRFFEELKAKYWNQSNLPNCPLSEDQE----GITLESLGGVFIAT 814

  Fly   964 IGGLLVSVFVAILEYCFRSRDSRSA----------SSGSGMGLGMGLGGGMSGGSLGKANGSMML 1018
            :.||::::....:|..:..:...:.          |||||
  Fly   815 LFGLVLAMMTLGMEVLYYKKKQNALEITQVRPVNDSSGSG------------------------- 854

  Fly  1019 GPSSAVPGGMPSSHQRSTLTDTMHAKAK 1046
            |.||..|....|:.:::.....:.|:.|
  Fly   855 GNSSTAPPTATSTTKQAWHIPVLEAEEK 882

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluRIB	NP_001261621.2	PBP1_iGluR_AMPA	43..478	CDD:107375	67/386 (17%)
		ANF_receptor	55..461	CDD:279440	64/369 (17%)
		PBP2_iGluR_AMPA	497..938	CDD:270433	131/477 (27%)
		Lig_chan	632..967	CDD:278489	84/366 (23%)
Ir8a	NP_727328.1	PBP2_iGluR_putative	383..786	CDD:270435	131/478 (27%)
		Lig_chan	520..818	CDD:278489	84/366 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	82	0.746	Domainoid score	I2907
eggNOG	1	0.900	-	-		E1_KOG1052
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000021
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.910