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Protein Alignment GluRIB and Grik1

DIOPT Version :9

Sequence 1:	NP_001261621.2	Gene:	GluRIB / 44484	FlyBaseID:	FBgn0264000	Length:	1182	Species:	Drosophila melanogaster
Sequence 2:	NP_001104587.1	Gene:	Grik1 / 29559	RGDID:	2732	Length:	949	Species:	Rattus norvegicus

Alignment Length:	988	Identity:	331/988 - (33%)
Similarity:	506/988 - (51%)	Gaps:	212/988 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 LGAIFEQGTDE----VQSAFKYAMLNHNLN-----VSSRRFELQAYVDVINTADAFKLSRLICNQ 99
            :|.|||...:|    .:.|||:|:.:.|.|     .::..:::|.    ||..|:|:.||..|:|
  Rat    39 IGGIFETVENEPVNVEELAFKFAVTSINRNRTLMPNTTLTYDIQR----INLFDSFEASRRACDQ 99

  Fly   100 FSRGVYSMLGAVSPDSFDTLHSYSNTFQMPFV-TPWFPEKVLTPSSGFLD-FALSMRPDY---HQ 159
            .:.||.::.|.....|...:.|..|..::|.: |.|     ..||....| |.:::.|||   .:
  Rat   100 LALGVAALFGPSHSSSVSAVQSICNALEVPHIQTRW-----KHPSVDSRDLFYINLYPDYAAISR 159

  Fly   160 AIIDTIQFYGWRKIIYLYDSHDGLLRLQQIYQGLRPGNESFQVELVKRISNVSMAIEFLH----- 219
            |::|.:.:|.|:.:..:|:...||:|||               ||:|..|..::.|:...
  Rat   160 AVLDLVLYYNWKTVTVVYEDSTGLIRLQ---------------ELIKAPSRYNIKIKIRQLPPAN 209

  Fly   220 -----TLEQIGRFENKHIVLDCPTEMAKQILIQHVRDLRLGRRT--YHYLLSGLVMDDRW--ESE 275
                 .|:::.:.:..:::.||..|.|.:||.|   .|.:|..|  |||..:.|   |.:  :.|
  Rat   210 KDAKPLLKEMKKSKEFYVIFDCSHETAAEILKQ---ILFMGMMTEYYHYFFTTL---DLFALDLE 268

  Fly   276 IIEFGAINITGFRIVDTNRRLVREFYDSW--KRLD--PQMSVGAGRESISAQAALMYDAVFVLVE 336
            :..:..:|:||||:::.:...|....:.|  :||.  |:...|.....::.:||||||||:::..
  Rat   269 LYRYSGVNMTGFRLLNIDNPHVSSIIEKWSMERLQAPPRPETGLLDGMMTTEAALMYDAVYMVAI 333

  Fly   337 AFNKILRKKPDQFRNNVQRRSQTLMVAQAAASTSSDGYNYSASGGGGGNGGAGGGFAGSDSGGSG 401
            |                ..|:..|.|:
  Rat   334 A----------------SHRASQLTVS-------------------------------------- 344

  Fly   402 GMASRALDCNTAKGWVNAWEHGDKISRYLRKVEIEGLTGDIKFN-DDGRRVNYTLHVVEM----- 460
                 :|.|:..|    .|..|.:....:::...:||||.|.|| .||.|.::.|.::.:
  Rat   345 -----SLQCHRHK----PWRLGPRFMNLIKEARWDGLTGRITFNKTDGLRKDFDLDIISLKEEGT 400

  Fly   461 -----TVNSAMVKVAE----WNDDAGLQPLNAKYVRLRPHVEFEKNRTYIVTTVLEEPYIMLKQV 516
                 .|:..:.||.:    ||.::||...:....|.....:...|||.||||:|||||:|.::
  Rat   401 EKASGEVSKHLYKVWKKIGIWNSNSGLNMTDGNRDRSNNITDSLANRTLIVTTILEEPYVMYRK- 464

  Fly   517 AFGEKLHGNNRFEGYCKDLADLLAKELGINYELRLVKDGNYGSEKSSAHGGWDGMVGELVRKEAD 581
             ..:.|:||:||||||.||...|:..||..|:::||.||.||::...  |.|:|||.||:...||
  Rat   465 -SDKPLYGNDRFEGYCLDLLKELSNILGFLYDVKLVPDGKYGAQNDK--GEWNGMVKELIDHRAD 526

  Fly   582 IAIAAMTITAERERVIDFSKPFMSLGISIMIKKPVKQTPGVFSFMNPLSQEIWVSVIFSYIGVSI 646
            :|:|.:|||..||:|||||||||:|||||:.:||....||||||:||||.:||:.|:.:.:|||.
  Rat   527 LAVAPLTITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLSPDIWMYVLLACLGVSC 591

  Fly   647 VLFFVSRFSPHEWRLVQQQPQQSQSPDPHAHHEQLANQQPPGIIGGAPLPAPPGPPTPGAQTAAG 711
            |||.::||:|:||.            :||                    |..|
  Rat   592 VLFVIARFTPYEWY------------NPH--------------------PCNP------------ 612

  Fly   712 AAALQAALSAGSPGSGGSSSAVVNEFSVWNSFWFSLAAFMQQGCDLSPRSVSGRIAAASWFFFTL 776
                             .|..|.|.|::.|||||.:.|.||||.:|.|:::|.||....|:||||
  Rat   613 -----------------DSDVVENNFTLLNSFWFGVGALMQQGSELMPKALSTRIVGGIWWFFTL 660

  Fly   777 ILISSYTANLAAFLTVERMVTPINSPEDLAMQTEVQYGTLLHGSTWDFFRRSQIGLHNKMWEYMN 841
            |:|||||||||||||||||.:||:|.:|||.||:::||.:..|||..||::|:|..:.|||.:|:
  Rat   661 IIISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGAVRDGSTMTFFKKSKISTYEKMWAFMS 725

  Fly   842 SRKH-VFVPTYDEGIKRVRNSKGKYALLVESPKNEYVNAREPCDTMKVGRNLDTKGFGIATPLGS 905
            ||:. ..|...||||:||..:  .||||:||...|||..|. |:..::|..:|:||:|:.||:||
  Rat   726 SRQQSALVKNSDEGIQRVLTT--DYALLMESTSIEYVTQRN-CNLTQIGGLIDSKGYGVGTPIGS 787

  Fly   906 ALKDPINLAVLTLKENGELIKLRNKWWYEKAECSTHKDGETSHSELSLSNVAGIFYILIGGLLVS 970
            ..:|.|.:|:|.|:|.|:|..::.|||  :......:|.:.: |.|.:.|:.|||.:|..||::|
  Rat   788 PYRDKITIAILQLQEEGKLHMMKEKWW--RGNGCPEEDSKEA-SALGVENIGGIFIVLAAGLVLS 849

  Fly   971 VFVAILEYCFRSR 983
            |||||.|:.::||
  Rat   850 VFVAIGEFLYKSR 862

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.