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Protein Alignment GluRIB and Gria1

DIOPT Version :9

Sequence 1:	NP_001261621.2	Gene:	GluRIB / 44484	FlyBaseID:	FBgn0264000	Length:	1182	Species:	Drosophila melanogaster
Sequence 2:	NP_001106796.1	Gene:	Gria1 / 14799	MGIID:	95808	Length:	907	Species:	Mus musculus

Alignment Length:	1029	Identity:	413/1029 - (40%)
Similarity:	563/1029 - (54%)	Gaps:	167/1029 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 GSGVGVSAQPSLTEKIPLGAIFEQGTDEVQSAFKYAMLNHNLNVSSRRFELQAYVDVINTADAFK 91
            |:.||.    :....|.:|.:|.....:..:||::|     |:..:...:|...:|::|.:|:|:
Mouse    14 GAVVGA----NFPNNIQIGGLFPNQQSQEHAAFRFA-----LSQLTEPPKLLPQIDIVNISDSFE 69

  Fly    92 LSRLICNQFSRGVYSMLGAVSPDSFDTLHSYSNTFQMPFVTPWFPEKVLTPSSGFLDFALSMRPD 156
            ::...|:|||:|||::.|.....:.:.|.|:.....:.|:||.||  |.|.:    .|.|.:||:
Mouse    70 MTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFP--VDTSN----QFVLQLRPE 128

  Fly   157 YHQAIIDTIQFYGWRKIIYLYDSHDGLLRLQQIYQGLRPGNESFQVELVKRISNVSMAIEFLHTL 221
            ..:|:|..|..|.|:..:|:||:..||..||::..  ....:::||..|..::........|  .
Mouse   129 LQEALISIIDHYKWQTFVYIYDADRGLSVLQRVLD--TAAEKNWQVTAVNILTTTEEGYRML--F 189

  Fly   222 EQIGRFENKHIVLDCPTEMAKQILIQHVRDLRLGRRTYHYLLSGLVMDDRWESEIIEFGAINITG 286
            :.:.:.:.:.:|:||.:|....||.|.|: |......|||:|:.|...|...::..|.|| |:||
Mouse   190 QDLEKKKERLVVVDCESERLNAILGQIVK-LEKNGIGYHYILANLGFMDIDLNKFKESGA-NVTG 252

  Fly   287 FRIVDTNRRLVREFYDSWKRLDPQMSVGAGRESISAQAALMYDAVFVLVEAFNKILRKKPDQFRN 351
            |::|:....:.......|:..|.:.......:.....:||.||.|.|:.|||..:.|::.|
Mouse   253 FQLVNYTDTIPARIMQQWRTSDARDHTRVDWKRPKYTSALTYDGVKVMAEAFQSLRRQRID---- 313

  Fly   352 NVQRRSQTLMVAQAAASTSSDGYNYSASGGGGGNGGAGGGFAGSDSGGSGGMASRALDC--NTAK 414
             :.||                           ||.|                     ||  |.|.
Mouse   314 -ISRR---------------------------GNAG---------------------DCLANPAV 329

  Fly   415 GWVNAWEHGDKISRYLRKVEIEGLTGDIKFNDDGRRVNYTLHVVEMTVNSAMVKVAEWNDDAGLQ 479
                .|..|..|.|.|::|..|||||:::||:.|||.||||||:||. :..:.|:..||:|....
Mouse   330 ----PWGQGIDIQRALQQVRFEGLTGNVQFNEKGRRTNYTLHVIEMK-HDGIRKIGYWNEDDKFV 389

  Fly   480 PLNAKYVRLRPHVEFEKNRTYIVTTVLEEPYIMLKQVAFGEKLHGNNRFEGYCKDLADLLAKELG 544
            |. |...:........:||||||||:||:||:|||:.|  .:..||:|:||||.:||..:||.:|
Mouse   390 PA-ATDAQAGGDNSSVQNRTYIVTTILEDPYVMLKKNA--NQFEGNDRYEGYCVELAAEIAKHVG 451

  Fly   545 INYELRLVKDGNYGSEKSSAHGGWDGMVGELVRKEADIAIAAMTITAERERVIDFSKPFMSLGIS 609
            .:|.|.:|.||.||:...... .|:|||||||...||:|:|.:|||..||.||||||||||||||
Mouse   452 YSYRLEIVSDGKYGARDPDTK-AWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGIS 515

  Fly   610 IMIKKPVKQTPGVFSFMNPLSQEIWVSVIFSYIGVSIVLFFVSRFSPHEWRLVQQQPQQSQSPDP 674
            ||||||.|..||||||::||:.|||:.::|:|||||:|||.||||||:||
Mouse   516 IMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEW--------------- 565

  Fly   675 HAHHEQLANQQPPGIIGGAPLPAPPGPPTPGAQTAAGAAALQAALSAGSPGSGGSSSAVVNEFSV 739
              |.|:.                                         ..|...::|...|||.:
Mouse   566 --HSEEF-----------------------------------------EEGRDQTTSDQSNEFGI 587

  Fly   740 WNSFWFSLAAFMQQGCDLSPRSVSGRIAAASWFFFTLILISSYTANLAAFLTVERMVTPINSPED 804
            :||.||||.||||||||:||||:||||....|:|||||:||||||||||||||||||:||.|.||
Mouse   588 FNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAED 652

  Fly   805 LAMQTEVQYGTLLHGSTWDFFRRSQIGLHNKMWEYMNSRK-HVFVPTYDEGIKRVRNSKGKYALL 868
            ||.|||:.||||..|||.:|||||:|.:..|||.||.|.: .|||.|.:||:.|||.||||||.|
Mouse   653 LAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYL 717

  Fly   869 VESPKNEYVNAREPCDTMKVGRNLDTKGFGIATPLGSALKDPINLAVLTLKENGELIKLRNKWWY 933
            :||..|||:..|:||||||||.|||:||:|||||.||||:.|:|||||.|.|.|.|.||::||||
Mouse   718 LESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKLKSKWWY 782

  Fly   934 EKAECSTHKDG-ETSHSELSLSNVAGIFYILIGGLLVSVFVAILEYCFRSRDSRSASSGSGM--- 994
            :|.||.:...| :...|.||||||||:||||||||.:::.||::|:|::||.......|..:
Mouse   783 DKGECGSKDSGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKSRSESKRMKGFCLIPQ 847

  Fly   995 ----------GLGMGLGGGMSGGSLGKANG---------SMMLGPSSAVPGGMP 1029
                      .|....|.|.||||....||         ||...|..:...|||
Mouse   848 QSINEAIRTSTLPRNSGAGASGGSGSGENGRVVSQDFPKSMQSIPCMSHSSGMP 901

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.