Protein Alignment GluRIB and LOC110438919

DIOPT Version :9

• Sequence 1: NP_001261621.2
• Gene: GluRIB / 44484
• FlyBaseID: FBgn0264000
• Length: 1182
• Species: Drosophila melanogaster
• Sequence 2: XP_021328141.1
• Gene: LOC110438919 / 110438919
• -ID: -
• Length: 1417
• Species: Danio rerio
• Alignment Length: 1072
• Identity: 228/1072 - (21%)
• Similarity: 402/1072 - (37%)
• Gaps: 334/1072 - (31%)

  Fly   131 VTPWFPEKVLTPSSGFLDFALSMRPDYHQAIIDTIQ--FYGWR-KIIYLYDS--HDGLLRLQQIY 190
            ||.::|        |:.||...:|        .||:  |.||. :.:.|.|.  .||..::|
Zfish    31 VTTYYP--------GYQDFVTKIR--------STIENSFVGWELEEVLLLDMSVDDGDAKIQ--- 76

  Fly   191 QGLRPGNESFQVELVKRISNVSMAIEFLHTLEQIGRFENKHIVLDCPTEMAKQILIQHVRDLRLG 255
                        .|:|::.:                    .::|...|:....|:.|....:.|.
Zfish    77 ------------NLLKKLQS--------------------PVILLYSTKEEANIIFQVAHSVGLT 109

  Fly   256 RRTYHYLLSGLVMDDRWESEIIEF--GAINITGFRIVDTNRRLVREFYDSWKRLDPQMSVGAGRE 318
            ...|.:::..||..|. :....||  |.|:::               ||.|         ..|.|
Zfish   110 GYGYTWIVPSLVAGDA-DHIPAEFPTGMISVS---------------YDEW---------DYGLE 149

  Fly   319 SISAQAALMYDAVFVLVEAFNKILRKKPDQFRNNVQRRSQTLMVAQAAASTSSDGYNYSASGGGG 383
                  |.:.|.|.|:..|.:.::          :.|...||:.::.
Zfish   150 ------ARVRDGVAVIATATSTMM----------MDRGPHTLLKSEC------------------ 180

  Fly   384 GNGGAGGGFAGSDSGGSGGMASRALDCNTAKGWVNAWEHGDKISRYLRKVEIEGLTGDIKFNDDG 448
                  .|.....|..:|                    :.:::.|||..|..||  .::.|::||
Zfish   181 ------HGAPDKKSPMTG--------------------NNNEVLRYLMNVTFEG--RNLSFSEDG 217

  Fly   449 RRVNYTLHVVEMTVNSAMVKVAEWNDDAGLQPLNAKYVRLRPHVEF-------EKNRTYIVTTVL 506
            .:::..|.::.:.......:|.:|.:.:    |:.|| .:.|..|.       |.:...|||  |
Zfish   218 YQMHPKLVIILLDKERQWDRVGKWENGS----LSMKY-HVWPRFELYSGPEAREDDHLSIVT--L 275

  Fly   507 EE-PYIMLKQVAFGEKLHGN---------------NRFE-----------GYCKDLADLLAKELG 544
            || |:::::.|   :.|.|.               |:.:           |:|.|:...:||.:.
Zfish   276 EEAPFVIVEDV---DPLSGTCMRNTVPCRKQLKALNQTQDSAVYIKRCCKGFCIDILKKIAKNVK 337

  Fly   545 INYELRLVKDGNYGSEKSSAHGGWDGMVGELVRKEADIAIAAMTITAERERVIDFSKPFMSLGIS 609
            ..|:|.||.:|.:|.:   .:|.|:|||||:|.|.|.:|:.::||..||..|||||.||:..|||
Zfish   338 FTYDLYLVTNGKHGKK---INGTWNGMVGEVVLKNAHMAVGSLTINEERSEVIDFSVPFIETGIS 399

  Fly   610 IMIKKPVKQTPGVFSFMNPLSQEIWVSVIFSYIGVSIVLFFVSRFSPHEWRLVQQQPQQSQSPDP 674
            :|:.:. ..|....:|:.|.|.::|:.:....:.||.:..|:..:.                 .|
Zfish   400 VMVSRS-NGTVSPSAFLEPFSADVWIMMFVMLLLVSAIAVFIFEYF-----------------SP 446

  Fly   675 HAHHEQLANQQPPGIIGGAPLPAPPGPPTPGAQTAAGAAALQAALSAGSPGSGGSSSAVVNEFSV 739
            ..::..||:.:                                  .||.|           .|::
Zfish   447 VGYNRCLADGR----------------------------------EAGGP-----------SFTI 466

  Fly   740 WNSFWFSLAAFMQQGCDL-SPRSVSGRIAAASWFFFTLILISSYTANLAAFLTVERMVTPINSPE 803
            ..:.|............: :||..:.:|..:.|.||.:|.::|||||||||:..|..|..::...
Zfish   467 GKAIWLLWGLVFNNSVPVQNPRGTTSKIMVSVWAFFAVIFLASYTANLAAFMIQEEYVDQVSGLS 531

  Fly   804 DLAMQT------EVQYGTLLHGSTWDFFRRSQIGLHNKMWEYMNSRKHVFVPTYDEGIKRVRNSK 862
            |...|.      ..::||:.:|||....|.:...:|:.|.:: :.|..|      |.::.::..|
Zfish   532 DKKFQNPNDFSPPFRFGTVPNGSTERNIRNNYRDMHSYMVKF-HQRNVV------EALESLKTGK 589

  Fly   863 GKYALLVESPKNEYVNAR-EPCD--TMKVGRNLDTKGFGIATPLGSALKDPINLAVLTLKENGEL 924
             ..|.:.::....|:..| |.|.  |:..|:...:.|:|||....|..|..::||:|.|..:||:
Zfish   590 -LDAFIYDAAVLNYMAGRDEGCKLVTIGSGKVFASTGYGIAIQKDSGWKRQVDLAILQLFGDGEM 653

  Fly   925 IKLRNKWWYEKAECSTHKDGETSHSELSLSNVAGIFYILIGGLLVSVFVAILE--------YCFR 981
            .:|...|.  ...|. |:..|...|:|.:.|:||:||:|...:.:|:...|.|        :||
Zfish   654 EELEALWL--TGICH-HEKNEVMSSQLDVDNMAGVFYMLGAAMALSLITFIAEHVFYWHMRFCF- 714

  Fly   982 SRDSRSASSGSGMGLGMGLGGGMSGGSL-------GKANGSMMLGPSSAVPGGMPSSHQRSTLTD 1039
                            ||:..|..|.:.       ...:|..:...|||:  ..||:...:|
Zfish   715 ----------------MGVCSGKPGFTFTISREIYSCIHGVEIEDKSSAL--NSPSATMNNT--- 758

  Fly  1040 TMHAKAKLTIQASRDYDNGRVGYLNCASLQYYPPAQLSATPPDAGDSLHMNAHGQVXHEHAQESR 1104
              |:.....::.::          |.|||     :.::.:|..|.|.:...:......|| :.|.
Zfish   759 --HSNILRLLRTAK----------NMASL-----SGVNGSPHSALDFIRRESSVYDISEH-RRSL 805

  Fly  1105 LXRTPC-APTI--RRIMANSRQETEKMMGGGH 1133
            ...:.| ||.:  ..:.::...|.|:..|..|
Zfish   806 AGHSDCKAPYLPDDNMFSDYISEVERTFGNLH 837

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluRIB	NP_001261621.2	PBP1_iGluR_AMPA	43..478	CDD:107375	60/353 (17%)
		ANF_receptor	55..461	CDD:279440	58/336 (17%)
		PBP2_iGluR_AMPA	497..938	CDD:270433	117/477 (25%)
		Lig_chan	632..967	CDD:278489	76/344 (22%)
LOC110438919	XP_021328141.1	PBP1_iGluR_NMDA_NR2	<1..255	CDD:107373	63/366 (17%)
		PBP2_iGluR_NMDA_Nr2	267..667	CDD:270436	118/481 (25%)
		DUF4013	<389..478	CDD:315788	24/151 (16%)
		NMDAR2_C	704..1417	CDD:313729	31/174 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170590911
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.740