Protein Alignment GluRIB and grik4

DIOPT Version :9

• Sequence 1: NP_001261621.2
• Gene: GluRIB / 44484
• FlyBaseID: FBgn0264000
• Length: 1182
• Species: Drosophila melanogaster
• Sequence 2: XP_031761990.1
• Gene: grik4 / 100490768
• XenbaseID: XB-GENE-1011875
• Length: 962
• Species: Xenopus tropicalis
• Alignment Length: 1010
• Identity: 314/1010 - (31%)
• Similarity: 498/1010 - (49%)
• Gaps: 217/1010 - (21%)

  Fly    15 LLWLTWSSGGGGGSGVGVSAQPSLTEKIPLGAIFEQGTDEVQSA----FKYAMLNHNLN-VSSRR 74
            ||||..|:|           .|||.    :.||.:   |.::.:    ....:..:.:| ...|:
 Frog    12 LLWLMKSAG-----------SPSLR----IAAILD---DPMECSRGERLSITLAKNRINRAPERQ 58

  Fly    75 FELQAYVDVINTA--DAFKLSRLICNQFSRGVYSMLG-AVSPDSFDTLHSYSNTFQMPFVTPWFP 136
            .:.:..||:....  ..::.:..:|....:||..:|| :.||.|...:.:.....::|.:
 Frog    59 GKARLEVDIFELLKDSEYETAETMCQILPKGVLGVLGPSYSPSSSSIISNICGEKEVPHI----- 118

  Fly   137 EKVLTPSSGFLDF------ALSMRP---DYHQAIIDTIQFYGWRKIIYLYDSHDGLLRLQQIYQG 192
             ||.|..  ||.|      .|::.|   |...|:...::|:.......:....:.||.|:::.:.
 Frog   119 -KVSTEE--FLRFQYQRFTTLNLHPSNTDISAAVATLLRFFNSTTACLICAKAECLLNLEKLLRQ 180

  Fly   193 LRPGNESFQVELVKRISNVSMAIEFLH-------TLEQIGRFENKHIVLDCPTEMAKQILIQHVR 250
            .             .||...:::..|.       .|::|...:...|::.....|:..||:: ..
 Frog   181 F-------------LISKDCLSVRMLDDTWDPTPLLKEIRDDKTSTIIVHANASMSHTILMK-AA 231

  Fly   251 DLRLGRRTYHYLLSGL-VMDDRWESEIIEFGAINITGFRIVDTNRRLVREF----YDSW-KRLDP 309
            :|.:....|.|:.:.| .:..|:||.:.:  .:||.||.:.:.:....:||    ..|| :..|.
 Frog   232 ELGMVTAYYTYIFTNLEFVLQRFESPLDD--RVNILGFSMFNQSHSYFKEFAHTLQQSWEENCDH 294

  Fly   310 QMSVGAGRESISAQAALMYDAVFVLVEAFNKILRKKPDQFRNNVQRRSQTLMVAQAAASTSSDGY 374
            ....|.     :..|||::|||:.:|.|..::             .|||.:.|
 Frog   295 SPFTGP-----ALSAALLFDAVYGIVSAVQEL-------------NRSQEIGV------------ 329

  Fly   375 NYSASGGGGGNGGAGGGFAGSDSGGSGGMASRALDCNTAKGWVNAWEHGDKISRYLRKVEIEGLT 439
                                           :.|.|.:::    .|:||..:..|||.||:||||
 Frog   330 -------------------------------KPLSCGSSQ----IWQHGTSLMNYLRMVELEGLT 359

  Fly   440 GDIKFNDDGRRVNYTLHVVEMTVNSAMVKVAEWNDDAGLQPLNAKYVRLRPHV-EFEKNRTYIVT 503
            |.::||..|:|.||.:.:::.| .:...::.:|:...||. ::.:|  ..|:. :...|:|.|||
 Frog   360 GHVEFNSKGQRSNYDMKIMQYT-KTGFQEIGQWHVTNGLN-MDKRY--FSPNASDTLVNKTLIVT 420

  Fly   504 TVL----EEPYIMLKQVAFGEKLHGNNRFEGYCKDLADLLAKELGINYELRLVKDGNYGSEKSSA 564
            |:|    |.||:|||  |..::|.||:|:||:|.|:...||..|..||::|||.||.||..:  .
 Frog   421 TILFFLQENPYLMLK--ANHQELEGNDRYEGFCVDMLKELAAILRFNYKIRLVADGVYGVPE--L 481

  Fly   565 HGGWDGMVGELVRKEADIAIAAMTITAERERVIDFSKPFMSLGISIMIKKPVKQTPGVFSFMNPL 629
            :|.|.||||||:.::||:|:|.:|||||||:|||||||||:|||||:.:..:.:.||.|||::|.
 Frog   482 NGTWTGMVGELISRKADLAVAGLTITAEREKVIDFSKPFMTLGISILYRVHMGRKPGYFSFLDPF 546

  Fly   630 SQEIWVSVIFSYIGVSIVLFFVSRFSPHEWRLVQQQPQQSQSPDPHAHHEQLANQQPPGIIGGAP 694
            |..:|:.::.:|:.||.|||.|:|.:|:||          .||.|.|.
 Frog   547 SPGVWLFMLLAYLAVSCVLFLVARLTPYEW----------YSPHPCAQ----------------- 584

  Fly   695 LPAPPGPPTPGAQTAAGAAALQAALSAGSPGSGGSSSAVVNEFSVWNSFWFSLAAFMQQGCDLSP 759
                                             |..:.:||::|:.||.||.:..|||||..::|
 Frog   585 ---------------------------------GRCNLLVNQYSLGNSLWFPVGGFMQQGSTIAP 616

  Fly   760 RSVSGRIAAASWFFFTLILISSYTANLAAFLTVERMVTPINSPEDLAMQTEVQYGTLLHGSTWDF 824
            |::|.|..:..|:.||||:||||||||||||||:||..||.|.:|||.||.::|||:..||:..|
 Frog   617 RALSTRCVSGVWWAFTLIIISSYTANLAAFLTVQRMDVPIESVDDLADQTTIEYGTIHGGSSMTF 681

  Fly   825 FRRSQIGLHNKMWEYMNSRK-HVFVPTYDEGIKRVRNSKGKYALLVESPKNEYVNAREPCDTMKV 888
            |:.|:...:.:||.||:|:: .|||.:.:|||.||.||  .||.|:||..|||...|. |:..:|
 Frog   682 FQNSRYQTYQRMWNYMHSKQPSVFVKSTEEGIARVLNS--NYAFLLESTMNEYYRQRN-CNLTQV 743

  Fly   889 GRNLDTKGFGIATPLGSALKDPINLAVLTLKENGELIKLRNKWWYEKAECSTHKDGETSHSELSL 953
            |..|||||:||..|:|||.:|..:||:|.|:||..|..|:.||| :..:|...:|...  ..|.:
 Frog   744 GGLLDTKGYGIGMPVGSAFRDEFDLAILQLQENNCLEDLKRKWW-DGGKCPKEEDHRA--KGLGM 805

  Fly   954 SNVAGIFYILIGGLLVSVFVAILEYCFRSRDSRSA 988
            .|:.|||.:||.||:|::.:|:||:.:..|::..:
 Frog   806 ENIGGIFVVLICGLIVAILIAMLEFLWTVRNAEDS 840

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluRIB	NP_001261621.2	PBP1_iGluR_AMPA	43..478	CDD:107375	91/464 (20%)
		ANF_receptor	55..461	CDD:279440	86/435 (20%)
		PBP2_iGluR_AMPA	497..938	CDD:270433	194/445 (44%)
		Lig_chan	632..967	CDD:278489	129/335 (39%)
grik4	XP_031761990.1	Periplasmic_Binding_Protein_type1	23..400	CDD:415822	95/474 (20%)
		PBP2_iGluR_kainate_KA1	414..788	CDD:270442	194/441 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG60082
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000021
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.020