DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GluRIID and grik5-like.1

DIOPT Version :9

Sequence 1:	NP_651982.1	Gene:	GluRIID / 44483	FlyBaseID:	FBgn0028422	Length:	902	Species:	Drosophila melanogaster
Sequence 2:	NP_001072565.1	Gene:	grik5-like.1 / 780020	XenbaseID:	XB-GENE-5860197	Length:	479	Species:	Xenopus tropicalis

Alignment Length:	463	Identity:	156/463 - (33%)
Similarity:	250/463 - (53%)	Gaps:	34/463 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   421 IVLISVATKPYASLVESIDTLIGNNQFQGYGVDLIKELADKLGFNFTF---RDGGNDYGSFNKTT 482
            :.:.::..:|::...||        ..:|:.:||:.|||..||||:|.   :||  .||:.::..
Frog    43 LTVTTIMEQPFSMKTES--------GMEGFCIDLLSELAQSLGFNYTIKEVKDG--RYGAKDQDG 97

  Fly   483 NSTSGMLKEIVEGRADLAITDLTITSEREEVIDFSIPFMNLGIAILYVKPQKAPPA-LFSFMDPF 546
            | .:||:.|::...||||:..||||..||..:.|:.|||..||:||..|...:..: ||.|:.||
Frog    98 N-WNGMVGEVLRKEADLAVAPLTITGARERELAFTKPFMQTGISILLRKDDVSENSYLFGFLTPF 161

  Fly   547 SSEVWLYLGIAYLGVSLCFFIIGRLSPIEWDNPYPCIEEPEELENQFTINNSLWFTTGALLQQGS 611
            |.|.|:.:.:||:..|||.|::|||||.||       .|....:|.|...|||||..||...||:
Frog   162 SKETWIGILVAYVVTSLCLFLVGRLSPCEW-------TELSTEQNNFNFLNSLWFGVGAFTLQGA 219

  Fly   612 EIAPKALSTRTISAIWWFFTLIMVSSYTANLAAFLTIEN-PTSPINSVKDLADNKDDVQYGAKRT 675
            |..||::|.|.|:.|||.|::::|::|.|:.||||..:: .|:.|.:.:||. |:..:::|...:
Frog   220 EPHPKSVSARIIAVIWWIFSIVLVAAYIASFAAFLNSDSMQTTNIQTFEDLV-NQRTLEFGTINS 283

  Fly   676 GSTRNFFSTSEEPIYIKMNEYLNAH-PEMLMENNQQGVDKVKSGTKYAFLMESTSIEFNTVRECN 739
            .||..||..|:.|.|..:.||::.. .|:|:::..:||.:||. :.||||.||...:....:.|:
Frog   284 SSTFQFFKNSKNPTYRMIYEYMDKRKDELLVKSFAEGVRRVKE-SNYAFLGESVMQDIMVAKHCD 347

  Fly   740 LTKVGDPLDEKGYGIAMVKNWPYRDKFNKALLELQEQGVLARLKNKWWNEVGAGVCSAKSDDDGP 804
            |.:....:..:|||||...:.|.....:.|:||..|.|.:..|:.|||:    ..|:.|. ..|.
Frog   348 LVRAPQIIAGRGYGIAASLDSPLIKPLSVAILEQTESGNIEYLRKKWWD----NTCNMKR-SAGW 407

  Fly   805 SELGVDNLSGIYVVLVIGSIISIIISILCWCYFVYKKAKNYEVPFCDALAEEF--RIVIRFSENE 867
            :.:....|.||:::|.||..:.:|.:::.........|...:...|.|.:||.  |:... .||:
Frog   408 NPVQPHTLGGIFLILGIGLALGVIAALVELVLKARNNADQQKKSCCSAFSEEMGERLGTN-KENQ 471

  Fly   868 RPLKSAQS 875
            ....||:|
Frog   472 GASDSAKS 479

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GluRIID	NP_651982.1	PBP1_iGluR_Kainate	35..397	CDD:107377
		ANF_receptor	46..380	CDD:279440
		PBP2_iGluR_Kainate	417..788	CDD:270432	134/372 (36%)
		Lig_chan	549..819	CDD:278489	94/271 (35%)
grik5-like.1	NP_001072565.1	PBP2_iGluR_non_NMDA_like	41..396	CDD:270403	134/372 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000021
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910