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Protein Alignment GluRIID and Gria3

DIOPT Version :9

Sequence 1:	NP_651982.1	Gene:	GluRIID / 44483	FlyBaseID:	FBgn0028422	Length:	902	Species:	Drosophila melanogaster
Sequence 2:	NP_001268858.2	Gene:	Gria3 / 53623	MGIID:	95810	Length:	888	Species:	Mus musculus

Alignment Length:	843	Identity:	285/843 - (33%)
Similarity:	450/843 - (53%)	Gaps:	66/843 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 SIRLGLITDDATDRIRQTFEHAISVVN-----NELGVPLVGETEQVAYGNSVQAFAQLCRLMQSG 92
            :|.:|.:....|.:....|..|:.:.|     .|....|....:.:...||.......|.....|
Mouse    27 TISIGGLFMRNTVQEHSAFRFAVQLYNTNQNTTEKPFHLNYHVDHLDSSNSFSVTNAFCSQFSRG 91

  Fly    93 VGAVFGPAARHTASHLLNACDSKDIPFIYPHLSWGSNPD-GFNLHPSPEDIANALYDIVNQFEWS 156
            |.|:||...:.:.:.|.:.|.:....|:.|  |:.::.| .|.:...|. :..|:..::..::|.
Mouse    92 VYAIFGFYDQMSMNTLTSFCGALHTSFVTP--SFPTDADVQFVIQMRPA-LKGAILSLLGYYKWE 153

  Fly   157 RFIFCYESAEYLKILDHLMTRYGIKGPVIKVMRYDLNLNGNYKSV--LRRI----RKSEDSRIVV 215
            :|::.|::.....||..:|     :..|....:......||.|.:  .|||    .:.::.|.::
Mouse   154 KFVYLYDTERGFSILQAIM-----EAAVQNNWQVTARSVGNIKDIQEFRRIIEEMDRRQEKRYLI 213

  Fly   216 VGSTTGVAELLRQAQQVGIMNEDYTYIIGNLNLHTFDLEEYKYSEANITGIRMFSPDQEEVRDLM 280
            ......:..:|.|...:|..:..|.|::.||......||...:..|||||.::.:.:...|:..:
Mouse   214 DCEVERINTILEQVVILGKHSRGYHYMLANLGFTDIVLERVMHGGANITGFQIVNNENPMVQQFI 278

  Fly   281 EKLHQELGESEPVNSGSTFITMEMALTYDAVRVIAETTKHLPYQPQMLNCSERHD------NVQP 339
            :: ...|.|.|...:.:..:....|||:||:.||||..::|  :.|.::.|.|..      |...
Mouse   279 QR-WVRLDEREFPEAKNAPLKYTSALTHDAILVIAEAFRYL--RRQRVDVSRRGSAGDCLANPAV 340

  Fly   340 DGSTFRNYMRSLE-IKEKTITGRIYFEGNVRK-GFTFDVIELQTSGLVKVGTWEEGKDFEFQRPP 402
            ..|...:..|:|: ::.:.:||.|.|:...|: .:|.||.|::.||..|.|.|.|.:.|
Mouse   341 PWSQGIDIERALKMVQVQGMTGNIQFDTYGRRTNYTIDVYEMKVSGSRKAGYWNEYERF------ 399

  Fly   403 QAVNFND----IDDGSLVNKTFIVLISVATKPYASLVESIDTLIGNNQFQGYGVDLIKELADKLG 463
              |.|:|    .|..|..|:| ||:.::...||....::.:.|.||.:::||.|||..|:|..:.
Mouse   400 --VPFSDQQISNDSSSSENRT-IVVTTILESPYVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVR 461

  Fly   464 FNFTFR-DGGNDYGSFNKTTNSTSGMLKEIVEGRADLAITDLTITSEREEVIDFSIPFMNLGIAI 527
            ..:... .|...||:.:..|...:||:.|:|.||||:|:..||||..||||||||.|||:|||:|
Mouse   462 IKYKLSIVGDGKYGARDPETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISI 526

  Fly   528 LYVKPQKAPPALFSFMDPFSSEVWLYLGIAYLGVSLCFFIIGRLSPIEW---DNPYPCIEEPEEL 589
            :..||||:.|.:|||:||.:.|:|:.:..||:|||:..|::.|.||.||   ||.    |||.:.
Mouse   527 MIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHLEDNN----EEPRDP 587

  Fly   590 E------NQFTINNSLWFTTGALLQQGSEIAPKALSTRTISAIWWFFTLIMVSSYTANLAAFLTI 648
            :      |:|.|.|||||:.||.:|||.:|:|::||.|.:..:|||||||::||||||||||||:
Mouse   588 QSPPDPPNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTV 652

  Fly   649 ENPTSPINSVKDLADNKDDVQYGAKRTGSTRNFFSTSEEPIYIKMNEYL-NAHPEMLMENNQQGV 712
            |...|||.|.:||| .:.::.||...:|||:.||..|:..:|.||..|: :|.|.:..:....||
Mouse   653 ERMVSPIESAEDLA-KQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTADGV 716

  Fly   713 DKV-KSGTKYAFLMESTSIEFNTVRE-CNLTKVGDPLDEKGYGIAMVKNWPYRDKFNKALLELQE 775
            .:| ||..|:|||:|||..|:...|: |:..|||..||.||||:|..|....|...|.|:|:|.|
Mouse   717 ARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALRTPVNLAVLKLSE 781

  Fly   776 QGVLARLKNKWWNEVGAGVCSAK--SDDDGPSELGVDNLSGIYVVLVIGSIISIIISILCWCY 836
            ||:|.:||||||.:  .|.|.||  ...|..|.|.:.|::|::.:||.|..::::::::.:||
Mouse   782 QGILDKLKNKWWYD--KGECGAKDSGSKDKTSALSLSNVAGVFYILVGGLGLAMMVALIEFCY 842

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.