Protein Alignment GluRIID and gria1b

DIOPT Version :10

• Sequence 1: NP_651982.1
• Gene: GluRIID / 44483
• FlyBaseID: FBgn0028422
• Length: 902
• Species: Drosophila melanogaster
• Sequence 2: NP_991293.1
• Gene: gria1b / 403044
• ZFINID: ZDB-GENE-020125-2
• Length: 917
• Species: Danio rerio
• Alignment Length: 854
• Identity: 279/854 - (32%)
• Similarity: 462/854 - (54%)
• Gaps: 81/854 - (9%)

  Fly    37 GLITDDATDRIRQTFEHAISVVNNELGVP-LVGETEQVAYGNSVQAFAQLCRLMQSGVGAVFGPA 100
            ||...|:.:  ...|..|:|..|:   || ||.:.:.|..|:|.......|.....||.|:.|..
Zfish    29 GLFPTDSHE--YDVFRFALSQHND---VPKLVPQVDMVDTGSSFAMTYAFCSQFSKGVYAIIGLY 88

  Fly   101 ARHTASHLLNACDSKDIPFIYPHLSWGSNPDGFNLHPSPEDIANALYDIVNQFEWSRFIFCYESA 165
            .|.|.:.|::.|.:..:.|:.|.....:| :.|.:...|| :.:||..:|..::|::|::.|.|.
Zfish    89 DRKTMNMLMSFCGALHVCFVTPSFPIDTN-NQFVIQLRPE-LQDALIALVEHYKWNKFVYMYSSD 151

  Fly   166 EYLKILDHLMTRYGIKGPVIKVMRYDLNLNGNYKSVLRRIRKSEDSRIVVVGSTTGVAELLR--Q 228
            ..|.:|..::.....|...:..:.:|......:...::.:...::.:|::......:..:|.  .
Zfish   152 SGLTVLQKILDTAAEKTWQVTSINFDTLTEAAFLKAIQDLDNKKEFKIILDCELERLNSILNLIA 216

  Fly   229 AQQVGIMNEDYTYIIGNLNLHTFDLEEYKYSEANITGIRMF---SPD-QEEVRDLMEKLHQELGE 289
            ||:..:.|  |.||:.||.....:|.|::...||:||.::.   :|. ...::|.:|      .:
Zfish   217 AQKKNLKN--YHYILANLGFLDLNLTEFRKGGANVTGFQLMNYTNPTVSRTIQDWLE------FD 273

  Fly   290 SEPVNSGSTFITMEMALTYDAVRVIAETTKHLPYQPQMLNCSERHDNVQ-------PDGSTFRNY 347
            |:.:.|....:....|||||.|.|:|...::|  :.|.::.|.|.:..:       |.|... :.
Zfish   274 SKDLKSPKRRLKYTGALTYDGVTVMATAFQNL--RKQRIDISRRGNAGECLANPPAPWGQGI-DI 335

  Fly   348 MRSL-EIKEKTITGRIYF--EGNVRKGFTFDVIELQTSGLVKVGTWEEGKDFEFQRPPQAVNFND 409
            .|:| :::.:.:||.:.|  :|: |..||..|:|...||..|||.|.:.:.:    ...|...|.
Zfish   336 QRALQQVQFEGLTGHVQFNDKGH-RTNFTVSVMEFGPSGPKKVGYWNQREKY----VSTATYSNM 395

  Fly   410 IDDG-SLVNKTFIVLISVATKPYASLVESIDTLIGNNQFQGYGVDLIKELADKLGFNFTFR-DGG 472
            :::. .|.|:|::| .::...||..|.::.:.|:||::::||.|:|..|:|..:|:::... .|.
Zfish   396 LNETFGLQNRTYVV-TTILEAPYVMLKKNHEQLVGNDKYEGYCVELAAEIAKHVGYSYRLELVGD 459

  Fly   473 NDYGSFNKTTNSTSGMLKEIVEGRADLAITDLTITSEREEVIDFSIPFMNLGIAILYVKPQKAPP 537
            ..||:.:..|...:||:.|:|.|:||:|:..||||..||||||||.|||:|||:|:..||.|:.|
Zfish   460 GKYGARDAETMMWNGMVGELVYGKADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPTKSKP 524

  Fly   538 ALFSFMDPFSSEVWLYLGIAYLGVSLCFFIIGRLSPIEW------------DNPYPCIEEPEELE 590
            .:|||:||.:.|:|:.:..||:|||:..|::.|.||.||            :...|...||.:..
Zfish   525 GVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHADDEEETADQQNQNQPPSPEPNQSP 589

  Fly   591 NQ------------------FTINNSLWFTTGALLQQGSEIAPKALSTRTISAIWWFFTLIMVSS 637
            ||                  |.|.|||||:.||.:|||.:|:|::||.|.:..:|||||||::||
Zfish   590 NQSQNQREEKQEKQPEHTNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISS 654

  Fly   638 YTANLAAFLTIENPTSPINSVKDLADNKDDVQYGAKRTGSTRNFFSTSEEPIYIKMNEYL-NAHP 701
            ||||||||||:|...|||.|.:||| .:.::.||....|||:.||..|:..::.||..|: :|.|
Zfish   655 YTANLAAFLTVERMVSPIESAEDLA-KQTEIAYGTLDGGSTKEFFRRSKIAVFEKMWSYMKSAEP 718

  Fly   702 EMLMENNQQGVDKV-KSGTKYAFLMESTSIEFNTVRE-CNLTKVGDPLDEKGYGIAMVKNWPYRD 764
            .:.::...:||.:| ||..|||:|:|||..|:...|: |:..|||..||.||||:|..|....|:
Zfish   719 TVFVKTTDEGVVRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALRN 783

  Fly   765 KFNKALLELQEQGVLARLKNKWWNEVGAGVCSAKSDD--DGPSELGVDNLSGIYVVLVIGSIISI 827
            ..|.|:|:|.|||:|.:||||||.:  .|.|.:...|  |..|.|.:.|::|::.:|:.|..:::
Zfish   784 PVNLAVLKLNEQGLLDKLKNKWWYD--KGECGSGGGDSKDKTSALSLSNVAGVFYILIGGLGLAM 846

  Fly   828 IISILCWCY 836
            :::::.:||
Zfish   847 LVALVEFCY 855

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluRIID	NP_651982.1	PBP1_iGluR_Kainate	35..400	CDD:380605	92/379 (24%)
		PBP2_iGluR_Kainate	417..788	CDD:270432	171/404 (42%)
		Lig_chan	547..819	CDD:459656	124/306 (41%)
gria1b	NP_991293.1	PBP1_iGluR_AMPA_GluR1	26..390	CDD:380613	92/383 (24%)
		PBP2_iGluR_AMPA_GluR1	404..812	CDD:270447	173/411 (42%)