Protein Alignment GluRIID and Ir25a

DIOPT Version :9

• Sequence 1: NP_651982.1
• Gene: GluRIID / 44483
• FlyBaseID: FBgn0028422
• Length: 902
• Species: Drosophila melanogaster
• Sequence 2: NP_001260049.1
• Gene: Ir25a / 33683
• FlyBaseID: FBgn0031634
• Length: 947
• Species: Drosophila melanogaster
• Alignment Length: 958
• Identity: 232/958 - (24%)
• Similarity: 386/958 - (40%)
• Gaps: 235/958 - (24%)

  Fly    36 LGLITDDATDRIRQTFEHA----ISVVNNE-----LGVPLVGETEQVAYGNSVQAFAQLCRLMQS 91
            |.|::..:.:...||.::.    |:.|:||     :.|.|....:.:.||.|||
  Fly    18 LSLLSSFSLEIAAQTTQNINVLFINEVDNEPAAKAVEVVLTYLKKNIRYGLSVQ----------- 71

  Fly    92 GVGAVFGPAARHTASHLLNACDSKDIPFI----YPHL---------------------------- 124
             :.::  .|.:..|..||.|..:|....|    .|||
  Fly    72 -LDSI--EANKSDAKVLLEAICNKYATSIEKKQTPHLILDTTKSGIASETVKSFTQALGLPTISA 133

  Fly   125 SWGSNPD--------------GFNLHPSPEDIANALYDIVNQFEWSRFIFCYESAEYLKILDHLM 175
            |:|...|              ...:.|..:.|..|:..||.....:.....|:.:   .::||
  Fly   134 SYGQQGDLRQWRDLDEAKQKYLLQVMPPADIIPEAIRSIVIHMNITNAAILYDDS---FVMDH-- 193

  Fly   176 TRYGIKGPVIKVMRYDLNLNGNYKSVLRRIRKSEDSRIVVVGSTTGVAELLRQAQQVGIMNEDYT 240
                                 .|||:|:.|   :...::...:..|..|...|.:::..::.:..
  Fly   194 ---------------------KYKSLLQNI---QTRHVITAIAKDGKREREEQIEKLRNLDINNF 234

  Fly   241 YIIGNLNLHTFDLEEYK--YSEANITGIRMFSPDQEEVRDLMEKLHQELGESEPVNSGSTFITME 303
            :|:|.|......||..|  |.|.|..               ...:.|..||.......:|.:.|:
  Fly   235 FILGTLQSIRMVLESVKPAYFERNFA---------------WHAITQNEGEISSQRDNATIMFMK 284

  Fly   304 -MALTYDAVRV-IAETTKHLPYQPQM-------------------------------LNCSE-RH 334
             ||.|....|: :..||.:|..:||:                               |||.: :.
  Fly   285 PMAYTQYRDRLGLLRTTYNLNEEPQLSSAFYFDLALRSFLTIKEMLQSGAWPKDMEYLNCDDFQG 349

  Fly   335 DNVQPDGSTFRNYMRSLEIKEKTITGRI--------YFEGNVRKGFTFDVIELQTSG-----LVK 386
            .|........|:|.  .:|.|.|..|..        .|.|:....|..|:..||..|     ...
  Fly   350 GNTPQRNLDLRDYF--TKITEPTSYGTFDLVTQSTQPFNGHSFMKFEMDINVLQIRGGSSVNSKS 412

  Fly   387 VGTWEEGKDFEFQRPPQAVNFNDIDDGSLVNKTFIVLISVATKPYASLVESIDTLIGNNQFQGYG 451
            :|.|..|.:.|.     .|.    |:..:.|.|...:..:.|...|..:...:|  ....::||.
  Fly   413 IGKWISGLNSEL-----IVK----DEEQMKNLTADTVYRIFTVVQAPFIMRDET--APKGYKGYC 466

  Fly   452 VDLIKELADKLGFNFTFR---DG--GN--DYGSFNKTTNSTSGMLKEIVEGRADLAITDLTITSE 509
            :|||.|:|..:.|::|.:   ||  ||  :.|.:|       |::|::::.:||:.:..:::.:|
  Fly   467 IDLINEIAAIVHFDYTIQEVEDGKFGNMDENGQWN-------GIVKKLMDKQADIGLGSMSVMAE 524

  Fly   510 REEVIDFSIPFMNL-GIAILYVKPQKAPPALFSFMDPFSSEVWLYLGIAYLGVSLCFFIIGRLSP 573
            ||.||||::|:.:| ||.|:..:| .:|.:||.|:....:.|||.:..||...|...:|..|.||
  Fly   525 REIVIDFTVPYYDLVGITIMMQRP-SSPSSLFKFLTVLETNVWLCILAAYFFTSFLMWIFDRWSP 588

  Fly   574 IEWDNPYPCIEEPEELENQFTINNSLWFTTGALLQQGSEIAPKALSTRTISAIWWFFTLIMVSSY 638
            ..:.|.....::.|| :.:|.:...|||...:|..||...|||.||.|.::|.||.|..|:::||
  Fly   589 YSYQNNREKYKDDEE-KREFNLKECLWFCMTSLTPQGGGEAPKNLSGRLVAATWWLFGFIIIASY 652

  Fly   639 TANLAAFLTIENPTSPINSVKDLADNKDDVQYGAKRTGSTRNFF---STSEEPIY-----IKMNE 695
            |||||||||:....:|:.|:.||| .:..:.|......|...:|   |..|:..|     :.:|:
  Fly   653 TANLAAFLTVSRLDTPVESLDDLA-KQYKILYAPLNGSSAMTYFERMSNIEQMFYEIWKDLSLND 716

  Fly   696 YLNA----------HP---------EMLMENN-----QQGVDKVKSGTK---YAFLMESTSIEFN 733
            .|.|          :|         :.:.|..     .:.|.:|::.|.   :|||.::|.|.:.
  Fly   717 SLTAVERSKLAVWDYPVSDKYTKMWQAMQEAKLPATLDEAVARVRNSTAATGFAFLGDATDIRYL 781

  Fly   734 TVRECNLTKVGDPLDEKGYGIAMVKNWPYRDKFNKALLELQEQGVLARLKNKWW-NEVGAGVCSA 797
            .:..|:|..||:....|.|.||:.:....:|:||.|:|.|..:..|.:||.||| |:.....|..
  Fly   782 QLTNCDLQVVGEEFSRKPYAIAVQQGSHLKDQFNNAILTLLNKRQLEKLKEKWWKNDEALAKCDK 846

  Fly   798 KSD-DDGPSELGVDNLSGIYVVLVIGSIISIIISILCWCYFVYKKAKN 844
            ..| .||   :.:.|:.|:::|:.:|  |.:....|.:.|:.|:..||
  Fly   847 PEDQSDG---ISIQNIGGVFIVIFVG--IGMACITLVFEYWWYRYRKN 889

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluRIID	NP_651982.1	PBP1_iGluR_Kainate	35..397	CDD:107377	87/464 (19%)
		ANF_receptor	46..380	CDD:279440	79/432 (18%)
		PBP2_iGluR_Kainate	417..788	CDD:270432	127/414 (31%)
		Lig_chan	549..819	CDD:278489	93/306 (30%)
Ir25a	NP_001260049.1	PBP1_iGluR_AMPA_Like	40..426	CDD:107378	84/450 (19%)
		PBP2_iGluR_putative	438..836	CDD:270435	124/409 (30%)
		Lig_chan	565..870	CDD:278489	95/311 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462880
Domainoid	1	1.000	82	0.746	Domainoid score	I2907
eggNOG	1	0.900	-	-		E1_KOG1052
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000021
OrthoInspector	1	1.000	-	-		mtm1027
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.840