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Protein Alignment GluRIID and Gria1

DIOPT Version :9

Sequence 1:	NP_651982.1	Gene:	GluRIID / 44483	FlyBaseID:	FBgn0028422	Length:	902	Species:	Drosophila melanogaster
Sequence 2:	NP_001106796.1	Gene:	Gria1 / 14799	MGIID:	95808	Length:	907	Species:	Mus musculus

Alignment Length:	930	Identity:	301/930 - (32%)
Similarity:	485/930 - (52%)	Gaps:	106/930 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 GNAYEASSGQSIRLGLITDDATDRIRQTFEHAISVVNNELGVP--LVGETEQVAYGNSVQAFAQL 85
            |....|:...:|::|.:..:...:....|..|:|    :|..|  |:.:.:.|...:|.:...:.
Mouse    14 GAVVGANFPNNIQIGGLFPNQQSQEHAAFRFALS----QLTEPPKLLPQIDIVNISDSFEMTYRF 74

  Fly    86 CRLMQSGVGAVFGPAARHTASHLLNACDSKDIPFIYPHLSWGSNPDGFNLHPSPEDIANALYDIV 150
            |.....||.|:||...|.|.:.|.:.|.:..:.||.|.....:: :.|.|...|| :..||..|:
Mouse    75 CSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFPVDTS-NQFVLQLRPE-LQEALISII 137

  Fly   151 NQFEWSRFIFCYESAEYLKILDHLMTRYGIKGPVIKVMRYDLNLNGNYKSVLRRIRKSEDSRIVV 215
            :.::|..|::.|::...|.:|..::.....|...:..:.........|:.:.:.:.|.::..:||
Mouse   138 DHYKWQTFVYIYDADRGLSVLQRVLDTAAEKNWQVTAVNILTTTEEGYRMLFQDLEKKKERLVVV 202

  Fly   216 VGSTTGVAELLRQAQQVGIMNEDYTYIIGNLNLHTFDLEEYKYSEANITGIRMFS-----PDQ-- 273
            ...:..:..:|.|..::......|.||:.||.....||.::|.|.||:||.::.:     |.:
Mouse   203 DCESERLNAILGQIVKLEKNGIGYHYILANLGFMDIDLNKFKESGANVTGFQLVNYTDTIPARIM 267

  Fly   274 -----EEVRDLMEKLHQELGESEPVNSGSTFITMEMALTYDAVRVIAETTKHLPYQPQMLNCSER 333
                 .:.||     |..:....|..:.        |||||.|:|:||..:.|  :.|.::.|.|
Mouse   268 QQWRTSDARD-----HTRVDWKRPKYTS--------ALTYDGVKVMAEAFQSL--RRQRIDISRR 317

  Fly   334 HDNVQPDGSTFRN----------YMRSL-EIKEKTITGRIYF-EGNVRKGFTFDVIELQTSGLVK 386
            .:    .|....|          ..|:| :::.:.:||.:.| |...|..:|..|||::..|:.|
Mouse   318 GN----AGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQFNEKGRRTNYTLHVIEMKHDGIRK 378

  Fly   387 VGTWEEGKDFEFQRPPQAVNFN-DIDDGSLVNKTFIVLISVATKPYASLVESIDTLIGNNQFQGY 450
            :|.|.|...|    .|.|.:.. ..|:.|:.|:|:|| .::...||..|.::.:...||::::||
Mouse   379 IGYWNEDDKF----VPAATDAQAGGDNSSVQNRTYIV-TTILEDPYVMLKKNANQFEGNDRYEGY 438

  Fly   451 GVDLIKELADKLGFNFTFR---DGGNDYGSFNKTTNSTSGMLKEIVEGRADLAITDLTITSEREE 512
            .|:|..|:|..:|:::...   ||  .||:.:..|.:.:||:.|:|.||||:|:..||||..|||
Mouse   439 CVELAAEIAKHVGYSYRLEIVSDG--KYGARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREE 501

  Fly   513 VIDFSIPFMNLGIAILYVKPQKAPPALFSFMDPFSSEVWLYLGIAYLGVSLCFFIIGRLSPIEWD 577
            |||||.|||:|||:|:..||||:.|.:|||:||.:.|:|:.:..||:|||:..|::.|.||.||.
Mouse   502 VIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWH 566

  Fly   578 NPYPCIEEPEE--------LENQFTINNSLWFTTGALLQQGSEIAPKALSTRTISAIWWFFTLIM 634
            :     ||.||        ..|:|.|.|||||:.||.:|||.:|:|::||.|.:..:|||||||:
Mouse   567 S-----EEFEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLII 626

  Fly   635 VSSYTANLAAFLTIENPTSPINSVKDLADNKDDVQYGAKRTGSTRNFFSTSEEPIYIKMNEYL-N 698
            :||||||||||||:|...|||.|.:||| .:.::.||....|||:.||..|:..::.||..|: :
Mouse   627 ISSYTANLAAFLTVERMVSPIESAEDLA-KQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKS 690

  Fly   699 AHPEMLMENNQQGVDKV-KSGTKYAFLMESTSIEFNTVRE-CNLTKVGDPLDEKGYGIAMVKNWP 761
            |.|.:.:...::|:.:| ||..|||:|:|||..|:...|: |:..|||..||.||||||..|...
Mouse   691 AEPSVFVRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSA 755

  Fly   762 YRDKFNKALLELQEQGVLARLKNKWWNEVGAGVCSAK--SDDDGPSELGVDNLSGIYVVLVIGSI 824
            .|...|.|:|:|.|||||.:||:|||.:  .|.|.:|  ...|..|.|.:.|::|::.:|:.|..
Mouse   756 LRGPVNLAVLKLSEQGVLDKLKSKWWYD--KGECGSKDSGSKDKTSALSLSNVAGVFYILIGGLG 818

  Fly   825 ISIIISILCWCYFVYKKAKNYEVPFCDALAEEFRIVIRFS-----------------ENERPL-- 870
            ::::::::.:||....::|..: .||....:.....||.|                 ||.|.:
Mouse   819 LAMLVALIEFCYKSRSESKRMK-GFCLIPQQSINEAIRTSTLPRNSGAGASGGSGSGENGRVVSQ 882

  Fly   871 ---KSAQSIYSRSRNSSQSI 887
               ||.|||...|.:|...:
Mouse   883 DFPKSMQSIPCMSHSSGMPL 902

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.