Protein Alignment GluRIID and grid1

DIOPT Version :10

• Sequence 1: NP_651982.1
• Gene: GluRIID / 44483
• FlyBaseID: FBgn0028422
• Length: 902
• Species: Drosophila melanogaster
• Sequence 2: NP_001096470.1
• Gene: grid1 / 100125089
• XenbaseID: XB-GENE-990290
• Length: 1009
• Species: Xenopus tropicalis
• Alignment Length: 865
• Identity: 213/865 - (24%)
• Similarity: 403/865 - (46%)
• Gaps: 102/865 - (11%)

  Fly    34 IRLGLITDDATDRIRQTFEHAIS--VVNNELGVPLVGETEQVAY-------GNSVQAFAQLCRLM 89
            |.:|.|.::...:..:.|:.|:|  .:|::     :.::|::.|       .|..||..:.|.||
 Frog    24 IHIGAIFEENAVKDDEVFQLAVSDLSLNDD-----ILQSEKITYSIKFIEANNPFQAVQEACDLM 83

  Fly    90 QSGVGAVFGPAARHTASHLLNACDSKDIPFIYPHLSWGSNPD---GFNLHPSPED---------- 141
            ..|:.|:.......:|:.|.:..|:..||.|:...:.|.:|.   .||  ||||.
 Frog    84 TQGILALVTSTGCASANALQSLTDAMHIPHIFVQRNSGGSPRTVCQFN--PSPEGEEYTLAARPP 146

  Fly   142 --IANALYDIVNQFEWSRFIFCYESAEYLKILDHLMTRYGIKGPVIKVMRYDLNLNGNYKSVLRR 204
              :.:.:..:|.:..|.:||..|:|...::.|...:.:....|..:.:.:.|.|::..:.::...
 Frog   147 VRLNDVMLKLVTELRWQKFIVFYDSDYDIRGLQGFLDQASRLGLDVSLQKVDRNISRVFATLFTS 211

  Fly   205 IRKSE-----DS--RIVVVGSTTGVAELLRQAQQVGIMNEDYTYIIGNLNLHTFDLEEYKYSE-A 261
            ::..|     |:  |.:::.|..|....:.:|.:..:.::|..::..|..::..::.|..:|. .
 Frog   212 MKTEELNRYRDTLRRAILLLSPRGAQSFISEAVETNLASKDSHWVYVNEEINDAEIVELVHSALG 276

  Fly   262 NITGIRMFSPDQEE--VRDLMEKLHQELGESEPVNSGSTFITMEMALTYDAVRVIA-------ET 317
            .||.||...|..::  :|.:...........:|.......:.:.....||:|.::|       |.
 Frog   277 RITVIRQIFPSLKDNNIRCVRNNHRIASLPCDPQEGYLQMLQVSNLYLYDSVLMLANAFHRKLED 341

  Fly   318 TKHLPYQPQMLNCSERHDNVQPDGSTFRNYMRSL--EIKEKTITGRI----YFEGNVRKGFTFDV 376
            .|.  :....|||..:.......|       ||:  .||:..|||..    :.|........|::
 Frog   342 RKW--HSMASLNCMRKSTKPWNGG-------RSMLDTIKKGRITGLTGIMEFKEAGANPHVQFEI 397

  Fly   377 IEL---QTSG--LVKVGTWEEGKDFEFQRPPQAVNFNDIDDGSLVNKTFIVLISVATKPYASLVE 436
            :..   :|.|  :.::.||:..|.|......:.:| ||:...:|      .:::|..:|:..:.|
 Frog   398 LGTSYSETFGKDVRRLATWDSMKGFNGSLQEKPLN-NDLQGLTL------KVVTVLEEPFVMVAE 455

  Fly   437 SIDTLIGN-NQFQGYGVDLIKELADKLGFNFTFRDGGNDYGSFNKTTNSTSGMLKEIVEGRADLA 500
            :|   :|. .:::|:.::::.||:::|||.:......:.......:..|.:||:.|::..|||:|
 Frog   456 NI---LGQPKRYKGFSIEILDELSNRLGFKYEIYQAPDGKYGHQLSNGSWNGMIGELINKRADIA 517

  Fly   501 ITDLTITSEREEVIDFSIPFMNLGIAILYVKPQKAPPALFSFMDPFSSEVWLYLGIAYLGVSLCF 565
            |:.:|||.|||.|:||:..:::..:.||..||::. ..:||...||...||..:......|.:..
 Frog   518 ISAITITPERENVVDFTKRYLDYSVGILIKKPEER-INIFSLFAPFDFAVWACIAAVIPVVGVLI 581

  Fly   566 FIIGRLSPIEWDNPYPCIEEPEELENQFTINNSLWFTTGALLQQGSEIAPKALSTRTISAIWWFF 630
            |::.|:..:...|     ..........|:::::|...||.:|||.|.|..:::.|.:...||.|
 Frog   582 FVLNRIQAVRAQN-----SSQTSQSTSSTLHSAIWIVYGAFVQQGGESAANSVAMRIVMGSWWLF 641

  Fly   631 TLIMVSSYTANLAAFLTIENPTSPINSVKDLADNKDDVQYGAKRTGSTRNFFSTSEEPIYIKMNE 695
            |||:.||||||||||||:....:||.:.:||| .:.|:.||..:..|...:|.:......::...
 Frog   642 TLIVCSSYTANLAAFLTVSRMDNPIRTFQDLA-KQVDLPYGTVKDSSVYEYFKSKGTNTLVQDRT 705

  Fly   696 YL--------NAHPEMLMENNQQGVDKVKSGTKYAFLMESTSIEFN--TVRECNLTKVGDPLDEK 750
            :.        |...:..:.:..:|:.|.|.| .||||.:.|.:|:.  |..||::...|:.:..|
 Frog   706 FAELWRTIGKNNGSDNCVSSPSEGIRKAKRG-NYAFLWDVTVVEYAALTDDECSVAVTGNTISSK 769

  Fly   751 GYGIAMVKNWPYRDKFNKALLELQEQGVLARLKNKWWNEVGAGVCSAKSDDDGPSE---LGVDNL 812
            |||||:....||||.|::.:||.|:.|.|..||.|||...|.  |...|.::..::   |.:.:.
 Frog   770 GYGIALQHGSPYRDIFSQRILEFQDSGRLDVLKEKWWPRTGR--CDLNSHNNAQNDGKALKLHSF 832

  Fly   813 SGIYVVLVIGSIISIIISIL 832
            :|::.:|.||.:::.:::.|
 Frog   833 AGVFCILAIGLLLACLVAAL 852

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluRIID	NP_651982.1	PBP1_iGluR_Kainate	35..400	CDD:380605	82/416 (20%)
		PBP2_iGluR_Kainate	417..788	CDD:270432	116/381 (30%)
		Lig_chan	547..819	CDD:459656	85/284 (30%)
grid1	NP_001096470.1	PBP1_iGluR_delta_1	25..426	CDD:380615	82/416 (20%)
		PBP2_iGluR_delta_1	437..807	CDD:270448	117/386 (30%)