Protein Alignment ear and YEATS4

DIOPT Version :9

• Sequence 1: NP_001262595.1
• Gene: ear / 44451
• FlyBaseID: FBgn0026441
• Length: 945
• Species: Drosophila melanogaster
• Sequence 2: NP_006521.1
• Gene: YEATS4 / 8089
• HGNCID: 24859
• Length: 227
• Species: Homo sapiens
• Alignment Length: 195
• Identity: 51/195 - (26%)
• Similarity: 82/195 - (42%)
• Gaps: 40/195 - (20%)

  Fly    10 GHTSKLRSKKTPHPQAFTHDWEIYVQGVNKADISAFVEKVVFVLHESFPKPKRVVKEPPYAIQES 74
            |:.::...||. .....||.|.:||:.....|:||:|:|:.|.||||:..|.|||.:|||.|.|:
Human    28 GNVARYFGKKR-EEDGHTHQWTVYVKPYRNEDMSAYVKKIQFKLHESYGNPLRVVTKPPYEITET 91

  Fly    75 GYAGFLLPVEIYFRNRDEPKRIVYQYDLVLQS---------TGPPQHHVEVKTHIFEAPSEEFRT 130
            |:..|.:.::|:|.:.:|....:|....:.||         |...:.:.|:   ||:.|:...:.
Human    92 GWGEFEIIIKIFFIDPNERPVTLYHLLKLFQSDTNAMLGKKTVVSEFYDEM---IFQDPTAMMQQ 153

  Fly   131 KLMRGGGVPVFGANIGAGSLARTLSPSVGSGETAHSNEMSGVKAKGVPGTISMNSDLNTGKKHKS 195
            .|                    |.|..:..|...|..|.:.::.|       ....|...||..|
Human   154 LL--------------------TTSRQLTLGAYKHETEFAELEVK-------TREKLEAAKKKTS 191

  Fly   196  195
            Human   192  191

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ear	NP_001262595.1	YEATS	27..107	CDD:281374	32/88 (36%)
YEATS4	NP_006521.1	YEATS_GAS41_like	19..155	CDD:341128	40/130 (31%)
		Diacetylated histone H3 binding. /evidence=ECO:0000269|PubMed:29900004, ECO:0000269|PubMed:30071723, ECO:0007744|PDB:5VNB, ECO:0007744|PDB:5XTZ	93..97		0/3 (0%)
		Interaction with MLLT10. /evidence=ECO:0000269|PubMed:11756182	163..227		8/36 (22%)
		Interaction with TACC1. /evidence=ECO:0000269|PubMed:11903063	168..227		7/31 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5033
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1482359at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820