Protein Alignment ear and Mllt3

DIOPT Version :9

• Sequence 1: NP_001262595.1
• Gene: ear / 44451
• FlyBaseID: FBgn0026441
• Length: 945
• Species: Drosophila melanogaster
• Sequence 2: NP_081602.3
• Gene: Mllt3 / 70122
• MGIID: 1917372
• Length: 569
• Species: Mus musculus
• Alignment Length: 941
• Identity: 215/941 - (22%)
• Similarity: 321/941 - (34%)
• Gaps: 393/941 - (41%)

  Fly     2 AVKVQFEIGHTSKLRSKKTPHPQAFTHDWEIYVQGVNKADISAFVEKVVFVLHESFPKPKRVVKE 66
            ||:|:.|:||.:::|.|  |..:.|||||.::|:|...::|..|||||||.||||||:||||.|:
Mouse     6 AVQVKLELGHRAQVRKK--PTVEGFTHDWMVFVRGPEHSNIQHFVEKVVFHLHESFPRPKRVCKD 68

  Fly    67 PPYAIQESGYAGFLLPVEIYFRNRDEPKRIVYQYDLVLQSTG-PPQHHVEVKTHIFEAPSEEFRT 130
            |||.::|||||||:||:|:||:|::|||::.:.|||.|...| ||.:|:..:...|..|:|:||.
Mouse    69 PPYKVEESGYAGFILPIEVYFKNKEEPKKVRFDYDLFLHLEGHPPVNHLRCEKLTFNNPTEDFRR 133

  Fly   131 KLMRGGGVPVFGANIGAGSLARTLSPSVGSGETAHSNEMSGVKAKGVPGTISMNSDLNT-GKKHK 194
            ||::.||.|....:..:.|.:.:.|.|..|..::.|:..|...:.....:.|.:|...: .|.||
Mouse   134 KLLKAGGDPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHK 198

  Fly   195 SRSEDPGKSNAFSALFGPPITKTSVTANNMAQVPVSKHSPEAKSAAVGGKGVFHEGREKASKDRD 259
            ...|...|.                          ||.|.|.|||       |.|    .|:|.:
Mouse   199 LMKEHKEKP--------------------------SKDSREHKSA-------FKE----PSRDHN 226

  Fly   260 KSSGGDKPREKDKKDRHGRDKDRKSSKSGDGKHER--DKEKSKKDKSRDKEREREQGSGNTTSAN 322
            |||               :|..:|..::...|.|:  .|...|:.|...||.:.:        :|
Mouse   227 KSS---------------KDSSKKPKENKPLKEEKIVPKMAFKEPKPMSKEPKAD--------SN 268

  Fly   323 ALTVATSVGTAGGLVKHTASPKPGKPNEMGAPSPKKTANDSAAGAVAPTSRSKERDEHKSVKSE- 386
            .|||     |:|             ..:..|||.:..|:||...:.....:|......||..|.
Mouse   269 LLTV-----TSG-------------QQDKKAPSKRPPASDSEELSAKKRKKSSSEALFKSFSSAP 315

  Fly   387 ------SKDKERSSSKKSKKDKKDKDKQRDESKDKRM--PKDERPGQSDSPASGNLQSAHLQQQS 443
                  |.||::...|...|..|.|.:.....|.|.|  |.|:....:||....|:.|....:|
Mouse   316 PLILTCSADKKQIKDKSHVKMGKVKIESETSEKKKSMLPPFDDIVDPNDSDVEENMSSKSDSEQ- 379

  Fly   444 QVASTGKATPTSVGSNSSSSMVSNIGKQKEEATGKHSEKAAESKGDKSTSNGNATDTKKSHKHKK 508
                   .:|.|..|:||||.                                 |.::...:...
Mouse   380 -------PSPASSSSSSSSSF---------------------------------TPSQTRQQGPL 404

  Fly   509 KEKSKDKEKERNDRDKDKDKERDKDKLKEREKDKQHVTGSEKSSTVDPSPKLEGASPATEGGAPD 573
            :...||...:.|:.:.|:.::.|.|...||                          |...||:..
Mouse   405 RSIMKDLHSDDNEEESDEAEDNDNDSEMER--------------------------PVNRGGSRS 443

  Fly   574 KTPVSASASSGSKKEKHKKSKEKSSGKDEKRQREAVDKQADTKHTGKSQQSQSGQSKTPSNLDLS 638
            :   ..|.|.||                                     .|:|..:.:|.:
Mouse   444 R---RVSLSDGS-------------------------------------DSESSSASSPLH---- 464

  Fly   639 DMDSAQSAPDLAATNALAAAAAATLQHSDSSNSSFPDLPARSSSQQKPTKGNTGSGKETKSTVKE 703
                .:..|.|..||
Mouse   465 ----HEPPPPLLKTN-------------------------------------------------- 475

  Fly   704 HKGKSKQNDKTLEKNTDKTEKPDKTPDPKVDKSEKSEKEDKKRNRRSSQSSNSGSGAGVTGAFIE 768
                   |::.||                                                  ::
Mouse   476 -------NNQILE--------------------------------------------------VK 483

  Fly   769 PPVKASKKEQGKAAGEKSKSPSLRPPRETNSTGTGGGTPNAGAGFLAPPSSSPSNNHSAAVAASL 833
            .|:|.||.::....||..|:
Mouse   484 SPIKQSKSDKQIKNGECDKA--------------------------------------------- 503

  Fly   834 NNNNNNNNNNTNSNSSHSPGEMTTPGQLQLPTEYLSELQELHHKIMTLQDNEELQHVVEMIAATG 898
                                             ||.||.|||.::|||::...||.:|.:|..||
Mouse   504 ---------------------------------YLDELVELHRRLMTLRERHILQQIVNLIEETG 535

  Fly   899 CYEITHKTFDFDLCKLDRGTVQRLQEFLATS 929
            .:.||:.|||||||.||:.||::||.:|.||
Mouse   536 HFHITNTTFDFDLCSLDKTTVRKLQSYLETS 566

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ear	NP_001262595.1	YEATS	27..107	CDD:281374	48/79 (61%)
Mllt3	NP_081602.3	YEATS	29..109	CDD:281374	48/79 (61%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	137..476		102/588 (17%)
		Nuclear localization signal. /evidence=ECO:0000255	296..301		0/4 (0%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167842606
Domainoid	1	1.000	118	1.000	Domainoid score	I5842
eggNOG	1	0.900	-	-		E1_COG5033
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	188	1.000	Inparanoid score	I3896
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003550
OrthoInspector	1	1.000	-	-		otm44211
orthoMCL	1	0.900	-	-		OOG6_108782
Panther	1	1.100	-	-	LDO	PTHR23195
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2426
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	11	10.840