Protein Alignment ear and mllt1b

DIOPT Version :9

• Sequence 1: NP_001262595.1
• Gene: ear / 44451
• FlyBaseID: FBgn0026441
• Length: 945
• Species: Drosophila melanogaster
• Sequence 2: XP_005171269.1
• Gene: mllt1b / 678639
• ZFINID: ZDB-GENE-060421-7142
• Length: 573
• Species: Danio rerio
• Alignment Length: 934
• Identity: 214/934 - (22%)
• Similarity: 331/934 - (35%)
• Gaps: 375/934 - (40%)

  Fly     3 VKVQFEIGHTSKLRSKKTPHPQAFTHDWEIYVQGVNKADISAFVEKVVFVLHESFPKPKRVVKEP 67
            |:|:.|:||.::||.|.|  .:.|||||.::|:|....||..|||:|||.||:||||||||.|||
Zfish     7 VQVKLELGHRAQLRKKVT--TEGFTHDWMVFVRGPEACDIQHFVERVVFRLHDSFPKPKRVCKEP 69

  Fly    68 PYAIQESGYAGFLLPVEIYFRNRDEPKRIVYQYDLVLQSTG-PPQHHVEVKTHIFEAPSEEFRTK 131
            ||.::||||||||:|:|:||:|::|||::.:.|||.|...| ||.:|:..:...|..|:.|||.|
Zfish    70 PYKVEESGYAGFLMPIEVYFKNKEEPKKVCFNYDLFLNLEGNPPVNHLRCEKLTFNNPTHEFRRK 134

  Fly   132 LMRGGGVPVFGANI-----GAGSLARTLSPSVGSGETAHSNEMSGVKAKGVPGTISMNSDLNTGK 191
            |::.||| .|.:..     ||..:.|. ||..
Zfish   135 LVKAGGV-FFSSQAIVVPEGAEMMPRP-SPDY--------------------------------- 164

  Fly   192 KHKSRSEDPGKSNAFSALFGPPITKTSVTANNMAQVPVSKHSPEAKSAAVGGKGVFHEGREKASK 256
                                 |:..|         :|:|..|...|..:      .|..:|.:
Zfish   165 ---------------------PMLPT---------IPLSAFSDPKKIKS------SHVVKESS-- 191

  Fly   257 DRDKSSGGDKPREKDKKDRHGRDKDRKSSKSGDGKHERDKEKSKKDKSRDKEREREQGSGNTTSA 321
             :|..||..|..:..|..:..:::.||.|:|               |:..:|.:||..|....|:
Zfish   192 -KDGGSGSSKSLKAHKATKEHQERTRKDSES---------------KATSRESDREGKSSRDLSS 240

  Fly   322 NALTVATSVGTAGGLVKHTASPKPGKPNEMGAPSPKKTANDSAAGAVAPTSRSKERDEHKSVKSE 386
            ::.:                               ||:.:            .:.:|:.|:|...
Zfish   241 SSFS-------------------------------KKSTD------------GRGKDDVKTVPKA 262

  Fly   387 SKDKERSSSKKSKKDKKDKDKQRDESKDKRMPKDERPGQSDSPASGNLQSAHLQQQSQVASTGKA 451
            :..:.:.:.::||.|                      |.|.....|             .:.|..
Zfish   263 AFKEPKLTVRESKMD----------------------GMSPKGGGG-------------VTVGVD 292

  Fly   452 TPTSVGSNSSSSMVSNIGKQKEEATGKHSEKAAESKGDKSTSNGNATDTKKSHKHKKKEKSKDKE 516
            |.|.....||::....:..:|::..|....|.    |..|:|:...|.|..|:..:||
Zfish   293 TRTPGKRPSSANESPKLSTKKQKRIGSEGMKG----GGYSSSSPRITSTTPSNYPEKK------- 346

  Fly   517 KERNDRDKDKDKERDKDKLKEREKDKQHVTGSEKSSTVDPSPKLEGASPATEGGAPDKTPVSASA 581
                                 ..|||.|.|
Zfish   347 ---------------------TTKDKGHWT----------------------------------- 355

  Fly   582 SSGSKKEKHKKSKEKSSGKDEKRQREAVDKQADTKHTGKSQQSQSGQSKTPSNLDLSDMDSAQSA 646
                        |.|:...:.|||.::.:..::.:.:.||:|                  ||.|:
Zfish   356 ------------KIKTEVAEVKRQPDSDESNSEDEASSKSEQ------------------SAPSS 390

  Fly   647 PDLAATNALAAAAAATLQHSDSSNSSFPDLPARSSSQQKPTKGNTGSGKETKSTVKEHKGKSKQN 711
            |                  |.||:||..|.....|.:|       |.| ..:|.|::...:...:
Zfish   391 P------------------SSSSSSSSSDSDFEPSQKQ-------GQG-TLRSMVEDMHSEGSDD 429

  Fly   712 DKTLEKNTDKTEKPDKTPDPKVDKSEKSEKEDKKRNRRSSQSSNSGSGAGVTGAFIEPPVKASKK 776
            |.:.|     .|.|.||.....|            :|.|..|.:.|:
Zfish   430 DSSSE-----VETPMKTTPFNHD------------SRLSMDSESDGN------------------ 459

  Fly   777 EQGKAAGEKSKSPSLRPPRETNSTGTGGGTPNAGAGFLAPPSSSPSNNHSAAVAASLNNNNNNNN 841
                   |:|:.||...|                         |||...|:|....|...:.::.
Zfish   460 -------EESRPPSQEAP-------------------------SPSLKLSSANLKMLGKKSPDSC 492

  Fly   842 NNTNSNSSHSPGEMTTPGQLQLPTEYLSELQELHHKIMTLQDNEELQHVVEMIAATGCYEITHKT 906
            |..         ::...|..::.|.|..||.:||.::|.|::...||.:|.:|..||.:.||:.|
Zfish   493 NRE---------KIIKRGYDKVGTAYTEELMDLHRRLMALRERNILQQIVNLIEKTGHFNITNTT 548

  Fly   907 FDFDLCKLDRGTVQRLQEFL-ATS 929
            |||||..||..||::||.:| |||
Zfish   549 FDFDLFSLDESTVRKLQSYLEATS 572

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ear	NP_001262595.1	YEATS	27..107	CDD:281374	49/79 (62%)
mllt1b	XP_005171269.1	YEATS	29..109	CDD:281374	49/79 (62%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587021
Domainoid	1	1.000	120	1.000	Domainoid score	I5714
eggNOG	1	0.900	-	-		E1_COG5033
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	189	1.000	Inparanoid score	I3881
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003550
OrthoInspector	1	1.000	-	-		otm25473
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23195
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5409
SonicParanoid	1	1.000	-	-		X2426
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	10	9.970