DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment scrib and AT5G07910

DIOPT Version :9

Sequence 1:	NP_001163746.1	Gene:	scrib / 44448	FlyBaseID:	FBgn0263289	Length:	2585	Species:	Drosophila melanogaster
Sequence 2:	NP_196408.2	Gene:	AT5G07910 / 830685	AraportID:	AT5G07910	Length:	262	Species:	Arabidopsis thaliana

Alignment Length:	226	Identity:	73/226 - (32%)
Similarity:	121/226 - (53%)	Gaps:	27/226 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   126 SQLKNLTVLGLNDMSLTTLPADFGSLTQ-LESLELRENLLKHLPETISQLTKLKRLDLGDNEIED 189
            |:.::..::||.|..|.|.|.:...:.: :.:|:|..|.:..:|..||:|..::||.:.||.:|.
plant    18 SRWRSTGIVGLRDSKLKTFPDEVIEMERAVRTLDLTHNKIADVPGEISKLINMQRLLIADNLVER 82

  Fly   190 LPPYLGYLPGLHELWLDHNQLQRLPPELGLLTKLTYLDVSENRLEELPNEISGLVSLTDLDLAQN 254
            ||..||.|..|..|.||.|::..||.|||.|.:|..|.:|                       :|
plant    83 LPGNLGKLQSLKVLMLDGNRISCLPDELGQLVRLEQLSIS-----------------------RN 124

  Fly   255 LLEALPDGIAKLSRLTILKLDQNRLQRLNDTLGNCENMQELILTENFLSELPASIGQMTKLNNLN 319
            :|..|||.|..|..|.:|.:..|||:.|.:::|:|.:::|:...:|.:.|||||:..:.:|.:|:
plant   125 MLIYLPDTIGSLRNLLLLNVSNNRLKSLPESVGSCASLEEVQANDNVVEELPASLCNLIQLKSLS 189

  Fly   320 VDRNALEYLP--LEIGQCANLGVLSLRDNKL 348
            :|.|.:..:|  |.| .|.:|..|||.:|.:
plant   190 LDNNQVNQIPDGLLI-HCKSLQNLSLHNNPI 219

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
scrib	NP_001163746.1	LRR_RI	13..283	CDD:238064	50/157 (32%)
		leucine-rich repeat	18..38	CDD:275380
		LRR_8	37..95	CDD:290566
		leucine-rich repeat	39..61	CDD:275380
		leucine-rich repeat	62..84	CDD:275380
		LRR_8	84..138	CDD:290566	3/11 (27%)
		leucine-rich repeat	85..107	CDD:275380
		leucine-rich repeat	108..130	CDD:275380	1/3 (33%)
		LRR_8	129..187	CDD:290566	17/58 (29%)
		leucine-rich repeat	131..153	CDD:275380	6/21 (29%)
		leucine-rich repeat	154..176	CDD:275380	7/21 (33%)
		leucine-rich repeat	177..199	CDD:275380	10/21 (48%)
		LRR_8	198..256	CDD:290566	15/57 (26%)
		leucine-rich repeat	200..222	CDD:275380	11/21 (52%)
		leucine-rich repeat	223..245	CDD:275380	3/21 (14%)
		LRR_8	267..325	CDD:290566	19/57 (33%)
		leucine-rich repeat	269..289	CDD:275380	7/19 (37%)
		leucine-rich repeat	292..314	CDD:275380	7/21 (33%)
		leucine-rich repeat	315..337	CDD:275380	8/23 (35%)
		LRR_4	337..375	CDD:289563	5/12 (42%)
		leucine-rich repeat	361..382	CDD:275380
		PDZ	728..816	CDD:214570
		PDZ_signaling	931..1016	CDD:238492
		PDZ	1239..1329	CDD:214570
		PDZ_signaling	1336..1425	CDD:238492
AT5G07910	NP_196408.2	LRR	<37..>219	CDD:227223	67/205 (33%)
		leucine-rich repeat	47..69	CDD:275380	7/21 (33%)
		leucine-rich repeat	70..92	CDD:275380	10/21 (48%)
		leucine-rich repeat	93..115	CDD:275380	11/21 (52%)
		leucine-rich repeat	116..161	CDD:275380	18/67 (27%)
		leucine-rich repeat	162..184	CDD:275380	7/21 (33%)
		leucine-rich repeat	185..208	CDD:275380	8/23 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910