DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment scrib and GSO1

DIOPT Version :9

Sequence 1:NP_001163746.1 Gene:scrib / 44448 FlyBaseID:FBgn0263289 Length:2585 Species:Drosophila melanogaster
Sequence 2:NP_193747.2 Gene:GSO1 / 827760 AraportID:AT4G20140 Length:1249 Species:Arabidopsis thaliana


Alignment Length:808 Identity:196/808 - (24%)
Similarity:323/808 - (39%) Gaps:209/808 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly     5 IPIFKGCNRQVEFVDKRHCSLP-QVPEEILRYSRTLEELFLDANHIRDL-PKNFFRLHRLRKLGL 67
            ||...|....:|.::..:.||. ::|.::...|: |:.|.|.||.::.| ||:...|..|:.|.|
plant   231 IPAELGRLENLEILNLANNSLTGEIPSQLGEMSQ-LQYLSLMANQLQGLIPKSLADLGNLQTLDL 294

  Fly    68 SDNEI-GRLPPDIQNFENLVELDVSRNDIP--------------------------DIPDDIKHL 105
            |.|.: |.:|.:..|...|::|.::.|.:.                          :||.::...
plant   295 SANNLTGEIPEEFWNMSQLLDLVLANNHLSGSLPKSICSNNTNLEQLVLSGTQLSGEIPVELSKC 359

  Fly   106 QSLQVADFSSNPIP-KLPSGFSQLKNLTVLGLNDMSLT-------------------------TL 144
            |||:..|.|:|.:. .:|....:|..||.|.|::.:|.                         .|
plant   360 QSLKQLDLSNNSLAGSIPEALFELVELTDLYLHNNTLEGTLSPSISNLTNLQWLVLYHNNLEGKL 424

  Fly   145 PADFGSLTQLESLELRENLLK-HLPETISQLTKLKRLDLGDNEIE-DLPPYLGYLPGLHELWLDH 207
            |.:..:|.:||.|.|.||... .:|:.|...|.||.:|:..|..| ::||.:|.|..|:.|.|..
plant   425 PKEISALRKLEVLFLYENRFSGEIPQEIGNCTSLKMIDMFGNHFEGEIPPSIGRLKELNLLHLRQ 489

  Fly   208 NQL-QRLPPELGLLTKLTYLDVSENRLE-ELPNEISGLVSLTDLDLAQNLLEA-LPDGIAKLSRL 269
            |:| ..||..||...:|..||:::|:|. .:|:....|..|..|.|..|.|:. |||.:..|..|
plant   490 NELVGGLPASLGNCHQLNILDLADNQLSGSIPSSFGFLKGLEQLMLYNNSLQGNLPDSLISLRNL 554

  Fly   270 TILKLDQNRLQRLNDT---------------------------LGNCENMQELILTENFLS-ELP 306
            |.:.|..|   |||.|                           |||.:|:..|.|.:|.|: ::|
plant   555 TRINLSHN---RLNGTIHPLCGSSSYLSFDVTNNGFEDEIPLELGNSQNLDRLRLGKNQLTGKIP 616

  Fly   307 ASIGQMTKLNNLNVDRNALE-YLPLE------------------------IGQCANLGVLSLRDN 346
            .::|::.:|:.|::..|||. .:||:                        :|:.:.||.|.|..|
plant   617 WTLGKIRELSLLDMSSNALTGTIPLQLVLCKKLTHIDLNNNFLSGPIPPWLGKLSQLGELKLSSN 681

  Fly   347 K-LKKLPPELGNCTVLHVLDVSGNQLL-YLPYSLVNL-QLKAVWLSENQ---SQP--------LL 397
            : ::.||.||.|||.|.||.:.||.|. .:|..:.|| .|..:.|.:||   |.|        |.
plant   682 QFVESLPTELFNCTKLLVLSLDGNSLNGSIPQEIGNLGALNVLNLDKNQFSGSLPQAMGKLSKLY 746

  Fly   398 TFQPDTDAETGEQVLSCYLLPQQ--EYQPITPARDLESDSEPFEEREPSRTVVKFSEEATQEKET 460
            ..:...::.|||       :|.:  :.|.:..|.||..::  |....|| |:...|:..|.:...
plant   747 ELRLSRNSLTGE-------IPVEIGQLQDLQSALDLSYNN--FTGDIPS-TIGTLSKLETLDLSH 801

  Fly   461 PFVRQNTP-HPKDLKAKAQ----------KLKVERSRNEEHANLVTLPEENGTKLAETPTE--TR 512
            ..:....| ...|:|:...          |||.:.||....:.|      ..|.|..:|..  .|
plant   802 NQLTGEVPGSVGDMKSLGYLNVSFNNLGGKLKKQFSRWPADSFL------GNTGLCGSPLSRCNR 860

  Fly   513 TIANNHQQQPHPVQQPIVGVNSKQPVVVGVVTPTTT-------------------------TVAP 552
            ..:||.||          |::::..|::..::..|.                         :.|.
plant   861 VRSNNKQQ----------GLSARSVVIISAISALTAIGLMILVIALFFKQRHDFFKKVGHGSTAY 915

  Fly   553 TGVQGGSE---------GASSTA---NNVKAATAAVVAELAATVGGSDEVQDDDEQEDEFESDRR 605
            |.....|:         |||.:.   .::..||..:..|.....|||.:|...:.:..|..:.::
plant   916 TSSSSSSQATHKPLFRNGASKSDIRWEDIMEATHNLSEEFMIGSGGSGKVYKAELENGETVAVKK 980

  Fly   606 VGFQVEGEDDDFYKRPPKLHRRDTPHHL 633
            :.::.:...:..:.|..|...|....||
plant   981 ILWKDDLMSNKSFSREVKTLGRIRHRHL 1008

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
scribNP_001163746.1 LRR_RI 13..283 CDD:238064 91/329 (28%)
leucine-rich repeat 18..38 CDD:275380 4/20 (20%)
LRR_8 37..95 CDD:290566 20/59 (34%)
leucine-rich repeat 39..61 CDD:275380 9/22 (41%)
leucine-rich repeat 62..84 CDD:275380 8/22 (36%)
LRR_8 84..138 CDD:290566 17/80 (21%)
leucine-rich repeat 85..107 CDD:275380 5/47 (11%)
leucine-rich repeat 108..130 CDD:275380 6/22 (27%)
LRR_8 129..187 CDD:290566 21/83 (25%)
leucine-rich repeat 131..153 CDD:275380 8/46 (17%)
leucine-rich repeat 154..176 CDD:275380 8/22 (36%)
leucine-rich repeat 177..199 CDD:275380 9/22 (41%)
LRR_8 198..256 CDD:290566 20/59 (34%)
leucine-rich repeat 200..222 CDD:275380 9/22 (41%)
leucine-rich repeat 223..245 CDD:275380 7/22 (32%)
LRR_8 267..325 CDD:290566 21/85 (25%)
leucine-rich repeat 269..289 CDD:275380 10/46 (22%)
leucine-rich repeat 292..314 CDD:275380 6/22 (27%)
leucine-rich repeat 315..337 CDD:275380 8/46 (17%)
LRR_4 337..375 CDD:289563 18/39 (46%)
leucine-rich repeat 361..382 CDD:275380 9/22 (41%)
PDZ 728..816 CDD:214570
PDZ_signaling 931..1016 CDD:238492
PDZ 1239..1329 CDD:214570
PDZ_signaling 1336..1425 CDD:238492
GSO1NP_193747.2 LRRNT_2 23..66 CDD:285463
PLN00113 25..1235 CDD:215061 196/808 (24%)
leucine-rich repeat 73..96 CDD:275380
leucine-rich repeat 97..120 CDD:275380
leucine-rich repeat 121..144 CDD:275380
leucine-rich repeat 145..168 CDD:275380
leucine-rich repeat 169..192 CDD:275380
leucine-rich repeat 193..240 CDD:275380 3/8 (38%)
leucine-rich repeat 217..237 CDD:275380 2/5 (40%)
LRR_RI 238..442 CDD:238064 47/204 (23%)
leucine-rich repeat 241..264 CDD:275380 4/22 (18%)
leucine-rich repeat 265..288 CDD:275380 9/22 (41%)
LRR_8 288..348 CDD:290566 11/59 (19%)
leucine-rich repeat 289..312 CDD:275380 8/22 (36%)
leucine-rich repeat 313..337 CDD:275380 3/23 (13%)
leucine-rich repeat 338..361 CDD:275380 2/22 (9%)
leucine-rich repeat 362..385 CDD:275380 6/22 (27%)
leucine-rich repeat 386..409 CDD:275380 5/22 (23%)
leucine-rich repeat 410..433 CDD:275380 3/22 (14%)
leucine-rich repeat 434..457 CDD:275380 8/22 (36%)
leucine-rich repeat 458..481 CDD:275380 9/22 (41%)
leucine-rich repeat 482..505 CDD:275380 9/22 (41%)
leucine-rich repeat 506..527 CDD:275380 6/20 (30%)
leucine-rich repeat 530..553 CDD:275380 9/22 (41%)
leucine-rich repeat 601..624 CDD:275380 6/22 (27%)
leucine-rich repeat 625..648 CDD:275380 7/22 (32%)
LRR_RI 649..843 CDD:238064 51/203 (25%)
leucine-rich repeat 649..672 CDD:275380 1/22 (5%)
leucine-rich repeat 673..696 CDD:275380 11/22 (50%)
leucine-rich repeat 697..720 CDD:275380 9/22 (41%)
leucine-rich repeat 721..744 CDD:275380 6/22 (27%)
leucine-rich repeat 745..768 CDD:275380 5/29 (17%)
leucine-rich repeat 769..793 CDD:275380 7/26 (27%)
leucine-rich repeat 818..838 CDD:275380 3/19 (16%)
PKc_like 957..1230 CDD:304357 10/52 (19%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

Return to query results.
Submit another query.