DRSC/TRiP Functional Genomics Resources

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Protein Alignment scrib and Ptar1

DIOPT Version :9

Sequence 1:NP_001163746.1 Gene:scrib / 44448 FlyBaseID:FBgn0263289 Length:2585 Species:Drosophila melanogaster
Sequence 2:NP_082484.1 Gene:Ptar1 / 72351 MGIID:1921875 Length:424 Species:Mus musculus


Alignment Length:310 Identity:65/310 - (20%)
Similarity:114/310 - (36%) Gaps:102/310 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly    24 SLPQVPEEILRYSRTLEELFLDANHIRDLPKNFFRLHRLRKLGLSDNEIGRLPPDIQNFENLVEL 88
            ||..||.|  |..|.::|                      ::.:.....||.|.:...:.:.:.:
Mouse   164 SLGAVPAE--RTQRIIQE----------------------EMEVCSEAAGRYPSNYNAWSHRIWV 204

  Fly    89 --DVSRNDIPDIPDDI---KHLQSLQVADFSSNPIPKLPSGFSQ----LKNLTVLGLNDMSLTTL 144
              :|::.|:..:.|::   ||..|:.|:|.         |||..    ||:|.            
Mouse   205 LQNVAKLDLKILLDELSSTKHWASMHVSDH---------SGFHYRQFLLKSLI------------ 248

  Fly   145 PADFGSLTQLESLELRENLLKHLP--ETISQLTKLKRLDLG---DNEIEDLPPYLGYLPGLHELW 204
                 |.|.::|...:.|.||..|  |..:..|:...::|.   :.|:|.....:...||...||
Mouse   249 -----SQTTIDSAVPQHNSLKSEPKDEAAAASTEEPSVNLPQLLEEEVEFCTDLIDSYPGHETLW 308

  Fly   205 --------LDHNQLQRLPPELGLLTKLTYLDVSENRLEELPNEISGLVSLTDLDLAQNLLEALP- 260
                    |.|:...||||.   ||.|:..|.....|.:         || .:..:..|.:|:. 
Mouse   309 CHRRHVFYLQHHLNGRLPPN---LTHLSPADCPGGALND---------SL-QIPTSPQLSQAMEV 360

  Fly   261 DGIAKLSRLTILKLDQNRLQR---------------LNDTLGNCENMQEL 295
            ||::..|:....: :..||:|               ::..|..|.|::::
Mouse   361 DGLSDSSKQGYSQ-ETKRLKRTPAPDSLGLEMEHRFIDQVLSTCRNVEQV 409

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
scribNP_001163746.1 LRR_RI 13..283 CDD:238064 62/296 (21%)
leucine-rich repeat 18..38 CDD:275380 6/13 (46%)
LRR_8 37..95 CDD:290566 6/59 (10%)
leucine-rich repeat 39..61 CDD:275380 1/21 (5%)
leucine-rich repeat 62..84 CDD:275380 3/21 (14%)
LRR_8 84..138 CDD:290566 14/62 (23%)
leucine-rich repeat 85..107 CDD:275380 5/26 (19%)
leucine-rich repeat 108..130 CDD:275380 6/25 (24%)
LRR_8 129..187 CDD:290566 12/62 (19%)
leucine-rich repeat 131..153 CDD:275380 2/21 (10%)
leucine-rich repeat 154..176 CDD:275380 6/23 (26%)
leucine-rich repeat 177..199 CDD:275380 3/24 (13%)
LRR_8 198..256 CDD:290566 17/65 (26%)
leucine-rich repeat 200..222 CDD:275380 9/29 (31%)
leucine-rich repeat 223..245 CDD:275380 3/21 (14%)
LRR_8 267..325 CDD:290566 7/44 (16%)
leucine-rich repeat 269..289 CDD:275380 4/34 (12%)
leucine-rich repeat 292..314 CDD:275380 0/4 (0%)
leucine-rich repeat 315..337 CDD:275380
LRR_4 337..375 CDD:289563
leucine-rich repeat 361..382 CDD:275380
PDZ 728..816 CDD:214570
PDZ_signaling 931..1016 CDD:238492
PDZ 1239..1329 CDD:214570
PDZ_signaling 1336..1425 CDD:238492
Ptar1NP_082484.1 PLN02789 89..>315 CDD:215423 41/200 (21%)
PPTA 180..207 CDD:279565 3/26 (12%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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