DRSC/TRiP Functional Genomics Resources

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Protein Alignment scrib and AgaP_AGAP007455

DIOPT Version :9

Sequence 1:NP_001163746.1 Gene:scrib / 44448 FlyBaseID:FBgn0263289 Length:2585 Species:Drosophila melanogaster
Sequence 2:XP_001687923.1 Gene:AgaP_AGAP007455 / 5666885 VectorBaseID:AGAP007455 Length:477 Species:Anopheles gambiae


Alignment Length:426 Identity:92/426 - (21%)
Similarity:159/426 - (37%) Gaps:104/426 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly   118 IPKLPSGFSQLKNLTVLGLNDMSLTTLPADFGSLTQLESLELRENLLKHLPETISQL-TKLKRLD 181
            |.||.....:||   ::.:.|.::..:..  ||:..|:            |:..|.: .||:::.
Mosquito    47 IVKLEDANHKLK---LVDIEDKTILNIKG--GSIVALQ------------PQHCSSVFAKLEKVS 94

  Fly   182 LGDNEIEDLPPYLGYLPGLHELWLDHNQLQRL--PPELGLLTKLTYLDVSENRLEELPNEISGLV 244
            :|...:::    |.:.|....:..:||:::.|  |.......::..|.:::|:||.: ..:...|
Mosquito    95 IGRVGLKE----LCFAPSFVYVSAEHNRIRTLHVPEAAPAAYRVEVLRLNDNQLESV-ESMRAFV 154

  Fly   245 SLTDLDLAQNLLEALPDG-IAKLSRLTILKLDQNRLQRLNDTLGNCENMQELILTENFLSELPAS 308
            :|.:|.|.:|.|..|... .|::.:|..|.|..|||..:..|      :.||        .||| 
Mosquito   155 ALKELHLERNALSTLDMACFAEMPKLEKLYLAYNRLNVIAST------VSEL--------SLPA- 204

  Fly   309 IGQMTKLNNLNVDRNALEYLPLEIGQCANLGVLSLRDNKLKKLPPELGNCTVLHVLDVSGNQLLY 373
                  |:.|.:..|.|....|......||.:|.|..|.|.|: ..|.|...|..:.::||:   
Mosquito   205 ------LSVLALQNNTLTVFDLRTWSLPNLELLELSANNLTKV-SGLDNVQALSDISLAGNR--- 259

  Fly   374 LPYSLVNLQLKAVWLSENQSQPLLTFQP-DTDAETGEQVLSCYLLPQQEYQPITPARDLESDS-- 435
                         |......|.|...:. |...:.|:  ::|              ..:.:.|  
Mosquito   260 -------------WQCHELDQMLEQLEKNDVTVKDGD--VNC--------------SGIRNSSIC 295

  Fly   436 -----EPFEEREPSRTVVKFS--EEATQEKETPFVRQNTPHPKDLKAKAQKLKVE-RSRNEEHAN 492
                 :|.||...: .:.||.  :|...|.|..|........:|.:||.:.||.. ..||||...
Mosquito   296 CTHVEQPTEETLQT-NLAKFDTLQERYGEMEARFNETVQKTIRDFEAKIRGLKESYEKRNEEVVP 359

  Fly   493 LVTLPEENGTKLAETPTETRTIANNHQQQPHPVQQP 528
            :...|            ||....|:.::|....:.|
Mosquito   360 VTPKP------------ETMDGGNDEEEQSTTDEMP 383

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
scribNP_001163746.1 LRR_RI 13..283 CDD:238064 38/168 (23%)
leucine-rich repeat 18..38 CDD:275380
LRR_8 37..95 CDD:290566
leucine-rich repeat 39..61 CDD:275380
leucine-rich repeat 62..84 CDD:275380
LRR_8 84..138 CDD:290566 5/19 (26%)
leucine-rich repeat 85..107 CDD:275380
leucine-rich repeat 108..130 CDD:275380 4/11 (36%)
LRR_8 129..187 CDD:290566 10/58 (17%)
leucine-rich repeat 131..153 CDD:275380 3/21 (14%)
leucine-rich repeat 154..176 CDD:275380 3/22 (14%)
leucine-rich repeat 177..199 CDD:275380 3/21 (14%)
LRR_8 198..256 CDD:290566 14/59 (24%)
leucine-rich repeat 200..222 CDD:275380 4/23 (17%)
leucine-rich repeat 223..245 CDD:275380 4/21 (19%)
LRR_8 267..325 CDD:290566 15/57 (26%)
leucine-rich repeat 269..289 CDD:275380 7/19 (37%)
leucine-rich repeat 292..314 CDD:275380 5/21 (24%)
leucine-rich repeat 315..337 CDD:275380 5/21 (24%)
LRR_4 337..375 CDD:289563 12/37 (32%)
leucine-rich repeat 361..382 CDD:275380 3/20 (15%)
PDZ 728..816 CDD:214570
PDZ_signaling 931..1016 CDD:238492
PDZ 1239..1329 CDD:214570
PDZ_signaling 1336..1425 CDD:238492
AgaP_AGAP007455XP_001687923.1 LRR_8 133..190 CDD:290566 16/57 (28%)
leucine-rich repeat 134..155 CDD:275380 4/21 (19%)
LRR_RI <137..330 CDD:238064 57/248 (23%)
leucine-rich repeat 156..179 CDD:275380 7/22 (32%)
LRR_8 178..238 CDD:290566 22/80 (28%)
leucine-rich repeat 180..204 CDD:275380 10/37 (27%)
leucine-rich repeat 205..227 CDD:275380 5/21 (24%)
leucine-rich repeat 228..249 CDD:275380 8/21 (38%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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