DRSC/TRiP Functional Genomics Resources

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Protein Alignment scrib and ppp1r7

DIOPT Version :9

Sequence 1:NP_001163746.1 Gene:scrib / 44448 FlyBaseID:FBgn0263289 Length:2585 Species:Drosophila melanogaster
Sequence 2:NP_001032463.1 Gene:ppp1r7 / 560323 ZFINID:ZDB-GENE-051113-288 Length:345 Species:Danio rerio


Alignment Length:321 Identity:86/321 - (26%)
Similarity:149/321 - (46%) Gaps:69/321 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly    16 EFVDKRHCSLPQVPE-EILRYSRTLEELFLDANHIRDLPKNFFRLHRLRKLGLSDNEIGRLPPDI 79
            |.||..||.:.::.. |:|..::|:.   |..|.|:.: :|...|..||:|.|.||:|.:| .::
Zfish    64 EDVDLVHCRIGKIEGLEVLLKAKTIS---LRQNLIKRI-ENLESLVSLRELDLYDNQIRKL-ENL 123

  Fly    80 QNFENLVELDVSRNDIPDIPDDIKHLQSLQVADFSSNPIPKLPSGFSQLKNLTVLGLNDMSLTTL 144
            |....|.:||||.|    :...|:.|.||                 :::|.|.:|.....|:   
Zfish   124 QALTELEQLDVSFN----LLRKIEGLDSL-----------------TKVKKLFLLHNKIASI--- 164

  Fly   145 PADFGSLTQLESLELRENLLKHLPETISQLTKLKRLDLGDNEIEDLPPYLGYLPGLHELWLDHNQ 209
             |:...||.|:.|||..|.::.: |.:..|:.|:.|.||.|:|..|.    .|.|||        
Zfish   165 -ANLDHLTSLQMLELGSNRIRVI-ENLDSLSSLESLFLGTNKITQLQ----NLDGLH-------- 215

  Fly   210 LQRLPPELGLLTKLTYLDVSENRLEELPNEISGLVSLTDLDLAQNLLEALPDGIAKLSRLTILKL 274
                        .||.|.:..||:.:|.. :..||:|.:|.|:.|.:|.: :|:....:|:.|.:
Zfish   216 ------------NLTVLSIQSNRITKLEG-LQNLVNLRELYLSHNGIEVM-EGLENNKKLSTLDI 266

  Fly   275 DQNRLQRLNDTLGNCENMQELILTEN------FLSELPASIGQMTKLNNLNVDRNALEYLP 329
            ..||:::: :.:.:..:::|..:.:|      .|.||..:.|    |..:.::||.|:..|
Zfish   267 AANRIKKI-ENISHLTDLKEFWMNDNQIENWADLDELKNAKG----LETVYLERNPLQKDP 322

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
scribNP_001163746.1 LRR_RI 13..283 CDD:238064 75/267 (28%)
leucine-rich repeat 18..38 CDD:275380 6/20 (30%)
LRR_8 37..95 CDD:290566 21/57 (37%)
leucine-rich repeat 39..61 CDD:275380 5/21 (24%)
leucine-rich repeat 62..84 CDD:275380 9/21 (43%)
LRR_8 84..138 CDD:290566 13/53 (25%)
leucine-rich repeat 85..107 CDD:275380 8/21 (38%)
leucine-rich repeat 108..130 CDD:275380 1/21 (5%)
LRR_8 129..187 CDD:290566 19/57 (33%)
leucine-rich repeat 131..153 CDD:275380 5/21 (24%)
leucine-rich repeat 154..176 CDD:275380 7/21 (33%)
leucine-rich repeat 177..199 CDD:275380 8/21 (38%)
LRR_8 198..256 CDD:290566 15/57 (26%)
leucine-rich repeat 200..222 CDD:275380 2/21 (10%)
leucine-rich repeat 223..245 CDD:275380 7/21 (33%)
LRR_8 267..325 CDD:290566 13/63 (21%)
leucine-rich repeat 269..289 CDD:275380 4/19 (21%)
leucine-rich repeat 292..314 CDD:275380 6/27 (22%)
leucine-rich repeat 315..337 CDD:275380 5/15 (33%)
LRR_4 337..375 CDD:289563
leucine-rich repeat 361..382 CDD:275380
PDZ 728..816 CDD:214570
PDZ_signaling 931..1016 CDD:238492
PDZ 1239..1329 CDD:214570
PDZ_signaling 1336..1425 CDD:238492
ppp1r7NP_001032463.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..53
LRR 1 62..83 6/18 (33%)
LRR 2 84..105 5/24 (21%)
LRR_8 86..139 CDD:290566 21/61 (34%)
LRR_4 86..124 CDD:289563 14/42 (33%)
leucine-rich repeat 86..106 CDD:275380 6/23 (26%)
LRR_4 106..147 CDD:289563 17/45 (38%)
LRR 3 106..127 9/21 (43%)
leucine-rich repeat 107..128 CDD:275380 9/21 (43%)
LRR_4 127..169 CDD:289563 15/66 (23%)
LRR 4 128..149 10/41 (24%)
leucine-rich repeat 129..150 CDD:275380 10/41 (24%)
LRR 5 150..171 5/24 (21%)
leucine-rich repeat 151..172 CDD:275380 6/24 (25%)
LRR 6 172..193 6/21 (29%)
leucine-rich repeat 173..216 CDD:275380 18/67 (27%)
LRR 7 194..215 9/24 (38%)
LRR_8 216..271 CDD:290566 17/56 (30%)
LRR_4 216..257 CDD:289563 14/42 (33%)
LRR 8 216..237 6/21 (29%)
leucine-rich repeat 217..238 CDD:275380 7/21 (33%)
LRR_4 238..279 CDD:289563 10/42 (24%)
LRR 9 238..259 6/21 (29%)
leucine-rich repeat 239..260 CDD:275380 6/21 (29%)
LRR_4 259..301 CDD:289563 7/42 (17%)
LRR 10 260..281 4/21 (19%)
leucine-rich repeat 261..282 CDD:275380 4/21 (19%)
LRR 11 282..303 4/20 (20%)
leucine-rich repeat 283..307 CDD:275380 5/23 (22%)
LRRcap 321..339 CDD:197729 1/2 (50%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.910

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