| Sequence 1: | NP_001163746.1 | Gene: | scrib / 44448 | FlyBaseID: | FBgn0263289 | Length: | 2585 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_060684.4 | Gene: | LRRC1 / 55227 | HGNCID: | 14307 | Length: | 524 | Species: | Homo sapiens |
| Alignment Length: | 505 | Identity: | 286/505 - (56%) |
|---|---|---|---|
| Similarity: | 369/505 - (73%) | Gaps: | 17/505 - (3%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 1 MFKCIPIFKGCNRQVEFVDKRHCSLPQVPEEILRYSRTLEELFLDANHIRDLPKNFFRLHRLRKL 65
Fly 66 GLSDNEIGRLPPDIQNFENLVELDVSRNDIPDIPDDIKHLQSLQVADFSSNPIPKLPSGFSQLKN 130
Fly 131 LTVLGLNDMSLTTLPADFGSLTQLESLELRENLLKHLPETISQLTKLKRLDLGDNEIEDLPPYLG 195
Fly 196 YLPGLHELWLDHNQLQRLPPELGLLTKLTYLDVSENRLEELPNEISGLVSLTDLDLAQNLLEALP 260
Fly 261 DGIAKLSRLTILKLDQNRLQRLNDTLGNCENMQELILTENFLSELPASIGQMTKLNNLNVDRNAL 325
Fly 326 EYLPLEIGQCANLGVLSLRDNKLKKLPPELGNCTVLHVLDVSGNQLLYLPYSLVNLQLKAVWLSE 390
Fly 391 NQSQPLLTFQPDTDAETGEQVLSCYLLPQ-------QEYQPITPA-RDLESD--SEPFEEREPSR 445
Fly 446 -TVVKFSEEATQEKET---PFVRQNTPHPKDLKAKAQKLKVERSRNEEHA 491 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| scrib | NP_001163746.1 | LRR_RI | 13..283 | CDD:238064 | 170/269 (63%) |
| leucine-rich repeat | 18..38 | CDD:275380 | 14/19 (74%) | ||
| LRR_8 | 37..95 | CDD:290566 | 42/57 (74%) | ||
| leucine-rich repeat | 39..61 | CDD:275380 | 14/21 (67%) | ||
| leucine-rich repeat | 62..84 | CDD:275380 | 18/21 (86%) | ||
| LRR_8 | 84..138 | CDD:290566 | 31/53 (58%) | ||
| leucine-rich repeat | 85..107 | CDD:275380 | 14/21 (67%) | ||
| leucine-rich repeat | 108..130 | CDD:275380 | 13/21 (62%) | ||
| LRR_8 | 129..187 | CDD:290566 | 32/57 (56%) | ||
| leucine-rich repeat | 131..153 | CDD:275380 | 11/21 (52%) | ||
| leucine-rich repeat | 154..176 | CDD:275380 | 14/21 (67%) | ||
| leucine-rich repeat | 177..199 | CDD:275380 | 12/21 (57%) | ||
| LRR_8 | 198..256 | CDD:290566 | 37/57 (65%) | ||
| leucine-rich repeat | 200..222 | CDD:275380 | 13/21 (62%) | ||
| leucine-rich repeat | 223..245 | CDD:275380 | 17/21 (81%) | ||
| LRR_8 | 267..325 | CDD:290566 | 33/57 (58%) | ||
| leucine-rich repeat | 269..289 | CDD:275380 | 11/19 (58%) | ||
| leucine-rich repeat | 292..314 | CDD:275380 | 12/21 (57%) | ||
| leucine-rich repeat | 315..337 | CDD:275380 | 14/21 (67%) | ||
| LRR_4 | 337..375 | CDD:289563 | 19/37 (51%) | ||
| leucine-rich repeat | 361..382 | CDD:275380 | 14/20 (70%) | ||
| PDZ | 728..816 | CDD:214570 | |||
| PDZ_signaling | 931..1016 | CDD:238492 | |||
| PDZ | 1239..1329 | CDD:214570 | |||
| PDZ_signaling | 1336..1425 | CDD:238492 | |||
| LRRC1 | NP_060684.4 | LRR 1 | 11..34 | 16/22 (73%) | |
| LRR_RI | 33..232 | CDD:238064 | 120/198 (61%) | ||
| LRR 2 | 35..58 | 14/22 (64%) | |||
| LRR_8 | 36..94 | CDD:290566 | 42/57 (74%) | ||
| leucine-rich repeat | 38..60 | CDD:275380 | 14/21 (67%) | ||
| LRR 3 | 60..81 | 16/20 (80%) | |||
| leucine-rich repeat | 61..83 | CDD:275380 | 18/21 (86%) | ||
| LRR 4 | 83..105 | 14/21 (67%) | |||
| leucine-rich repeat | 84..106 | CDD:275380 | 14/21 (67%) | ||
| leucine-rich repeat | 107..129 | CDD:275380 | 13/21 (62%) | ||
| LRR 5 | 107..126 | 12/18 (67%) | |||
| LRR 6 | 127..149 | 11/21 (52%) | |||
| LRR_8 | 129..186 | CDD:290566 | 32/56 (57%) | ||
| leucine-rich repeat | 130..152 | CDD:275380 | 11/21 (52%) | ||
| LRR 7 | 150..172 | 13/21 (62%) | |||
| leucine-rich repeat | 153..175 | CDD:275380 | 14/21 (67%) | ||
| LRR 8 | 173..196 | 12/22 (55%) | |||
| leucine-rich repeat | 176..198 | CDD:275380 | 12/21 (57%) | ||
| LRR 9 | 198..218 | 11/19 (58%) | |||
| leucine-rich repeat | 199..221 | CDD:275380 | 13/21 (62%) | ||
| LRR 10 | 219..242 | 16/22 (73%) | |||
| leucine-rich repeat | 222..244 | CDD:275380 | 17/21 (81%) | ||
| LRR_8 | 225..278 | CDD:290566 | 39/52 (75%) | ||
| LRR 11 | 244..264 | 14/19 (74%) | |||
| leucine-rich repeat | 245..267 | CDD:275380 | 15/21 (71%) | ||
| LRR 12 | 265..288 | 12/22 (55%) | |||
| LRR 13 | 290..310 | 11/19 (58%) | |||
| leucine-rich repeat | 291..313 | CDD:275380 | 12/21 (57%) | ||
| LRR 14 | 311..334 | 14/22 (64%) | |||
| leucine-rich repeat | 314..336 | CDD:275380 | 14/21 (67%) | ||
| LRR 15 | 336..356 | 8/19 (42%) | |||
| LRR 16 | 357..380 | 15/22 (68%) | |||
| leucine-rich repeat | 360..381 | CDD:275380 | 14/20 (70%) | ||
| LRR 17 | 382..405 | 19/22 (86%) | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 1 | 1.000 | 56 | 1.000 | Domainoid score | I11031 |
| eggNOG | 1 | 0.900 | - | - | E33208_3BA7S | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D148064at33208 | |
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 1 | 1.000 | - | - | otm42158 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_102427 | |
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R2604 |
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 7 | 6.750 | |||||