back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment scrib and lrrc28

DIOPT Version :9

Sequence 1:	NP_001163746.1	Gene:	scrib / 44448	FlyBaseID:	FBgn0263289	Length:	2585	Species:	Drosophila melanogaster
Sequence 2:	NP_001005442.1	Gene:	lrrc28 / 448029	XenbaseID:	XB-GENE-957286	Length:	367	Species:	Xenopus tropicalis

Alignment Length:	306	Identity:	94/306 - (30%)
Similarity:	133/306 - (43%)	Gaps:	61/306 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   129 KNLTVLGLNDMSLTTLPADF---GSLTQLESLELRENLLKHLPETISQLTKLKRLDLGDNEIEDL 190
            |||.   ||..:|...|.:.   ..|..||.|.::.|.|..|||.::|
Frog    18 KNLF---LNYRNLNHFPLELLKDEGLQYLERLYMKRNSLTTLPENLAQ----------------- 62

  Fly   191 PPYLGYLPGLHELWLDHNQLQRLPPELGLLTKLTYLDVSENRLEELPNEISGLVSLTDLDLAQNL 255
                 .||.|.||:|..|.:..:|..:|.|.||..||:|.|.||.|..:|..|.||..|.|..|.
Frog    63 -----KLPNLVELYLHSNNIVFVPEAIGSLVKLQSLDLSNNALEILCPDIGRLKSLRHLRLTNNR 122

  Fly   256 LEALPDGIAKLSRLTILKLDQNRLQRLNDTLGNCENMQELILTENFLSELPASIGQMTKLNNLNV 320
            |:.||..|.||..|..|.|..|.|..|.:.|..|:::|.|.:..|.|..:|..:.|:..||.|::
Frog   123 LKFLPPEIGKLKELQTLDLSTNHLVSLPEKLYQCQSLQYLTVDRNLLCSIPRQLCQLASLNELSM 187

  Fly   321 DRNALEYLPLEIGQCANLGVLSLRDN-KLKKLPPELGNCTVLHVLDVSG---------NQLLYLP 375
            ..|.|..|||::|:...|..:.:.:| :||.||..|.|    .|:..||         |:||...
Frog   188 AGNRLASLPLDLGRSRELQYVYVDNNVQLKGLPSYLYN----KVIGCSGCGSPVPLTENKLLSFT 248

  Fly   376 YSLVNLQLKAVWLSENQSQPLLTFQPDTDAETGEQVLSCYLLPQQE 421
            ...:::.:.|...|...:         ||          ::||.||
Frog   249 SGQLSIHVPAEVKSIGSA---------TD----------FVLPLQE 275

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.