Protein Alignment scrib and lrr1

DIOPT Version :9

• Sequence 1: NP_001163746.1
• Gene: scrib / 44448
• FlyBaseID: FBgn0263289
• Length: 2585
• Species: Drosophila melanogaster
• Sequence 2: NP_989278.1
• Gene: lrr1 / 394892
• XenbaseID: XB-GENE-1006187
• Length: 418
• Species: Xenopus tropicalis
• Alignment Length: 308
• Identity: 88/308 - (28%)
• Similarity: 128/308 - (41%)
• Gaps: 54/308 - (17%)

  Fly   126 SQLKNLTVLGLNDMSLTTLPADFGSLTQLESLELRENLLKHL-PETISQLTKLKRLDLGDNEIED 189
            |.|||.    ::.:.|....||.|::           ||..| |...|::.| .|..:.....:|
 Frog    95 SSLKNF----ISAVGLANKGADIGTV-----------LLPRLTPAKTSEIEK-PRAKMFITTKKD 143

  Fly   190 LPPYLGYLPGLHELWLDHNQLQRLPPELGLLTKLTYLDVSENRLEELPNEISGLVSLTDLDLAQN 254
            .|....:...|..|.:.:.:|.|:...:..|.||..||:|.|.:::||..|..||.|.:|.|..|
 Frog   144 YPITKSFPYSLEHLQVSYCKLARVDMRMLCLKKLQKLDLSNNHIKKLPKTIGDLVCLQELILNNN 208

  Fly   255 LLEALPDGIAKLSRLTILKLDQNRLQRLNDTLGNCENMQELILTENFLSELPASIGQMTKLNNLN 319
            |||:....:...:              |.|||      :.|.|:.|.|..||..|....:|.:|.
 Frog   209 LLESFEVVLCSTT--------------LRDTL------KSLDLSANKLKALPVQICNFKELVSLK 253

  Fly   320 VDRNALEYLPLEIGQCANLGVLSLRDNKLKKLPPELGNCTVLHVLDVSGNQLLYLPYSLVNLQLK 384
            :|.|.|..||..|||.:.|..||...|||:.||......: |..||:.||..:.....:.::|||
 Frog   254 LDENELLQLPFPIGQLSKLRFLSATKNKLQCLPNTFKKLS-LEKLDLFGNPFIQATPLVPDIQLK 317

  Fly   385 AVWLSENQSQPLLTFQPDTDAETGEQVLSCYLLPQQEYQ-PITPARDL 431
            .       ..|||        ||..:....|.:|...:. |.|..:||
 Frog   318 I-------PLPLL--------ETATRATLNYRIPYGPHLIPATLCQDL 350

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scrib	NP_001163746.1	LRR_RI	13..283	CDD:238064	40/157 (25%)
		leucine-rich repeat	18..38	CDD:275380
		LRR_8	37..95	CDD:290566
		leucine-rich repeat	39..61	CDD:275380
		leucine-rich repeat	62..84	CDD:275380
		LRR_8	84..138	CDD:290566	4/11 (36%)
		leucine-rich repeat	85..107	CDD:275380
		leucine-rich repeat	108..130	CDD:275380	2/3 (67%)
		LRR_8	129..187	CDD:290566	13/58 (22%)
		leucine-rich repeat	131..153	CDD:275380	4/21 (19%)
		leucine-rich repeat	154..176	CDD:275380	5/22 (23%)
		leucine-rich repeat	177..199	CDD:275380	3/21 (14%)
		LRR_8	198..256	CDD:290566	20/57 (35%)
		leucine-rich repeat	200..222	CDD:275380	5/21 (24%)
		leucine-rich repeat	223..245	CDD:275380	9/21 (43%)
		LRR_8	267..325	CDD:290566	15/57 (26%)
		leucine-rich repeat	269..289	CDD:275380	4/19 (21%)
		leucine-rich repeat	292..314	CDD:275380	7/21 (33%)
		leucine-rich repeat	315..337	CDD:275380	10/21 (48%)
		LRR_4	337..375	CDD:289563	13/37 (35%)
		leucine-rich repeat	361..382	CDD:275380	5/20 (25%)
		PDZ	728..816	CDD:214570
		PDZ_signaling	931..1016	CDD:238492
		PDZ	1239..1329	CDD:214570
		PDZ_signaling	1336..1425	CDD:238492
lrr1	NP_989278.1	LRR	<145..>310	CDD:227223	58/185 (31%)
		leucine-rich repeat	154..176	CDD:275380	5/21 (24%)
		leucine-rich repeat	177..199	CDD:275380	9/21 (43%)
		leucine-rich repeat	200..225	CDD:275380	8/38 (21%)
		leucine-rich repeat	226..248	CDD:275380	8/27 (30%)
		leucine-rich repeat	249..271	CDD:275380	10/21 (48%)
		leucine-rich repeat	272..293	CDD:275380	8/20 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910