Protein Alignment scrib and ics

DIOPT Version :9

• Sequence 1: NP_001163746.1
• Gene: scrib / 44448
• FlyBaseID: FBgn0263289
• Length: 2585
• Species: Drosophila melanogaster
• Sequence 2: NP_001285902.1
• Gene: ics / 34774
• FlyBaseID: FBgn0028546
• Length: 283
• Species: Drosophila melanogaster
• Alignment Length: 237
• Identity: 72/237 - (30%)
• Similarity: 124/237 - (52%)
• Gaps: 17/237 - (7%)

  Fly     4 CIPIFKGCNRQVEFVDK-RHCSLPQVPEEILRYSRTLEELFLDANHIRDLPKNFFRLHRLRKLGL 67
            |||:....::..:.:|: |....|::         .|.:..|.:  ..:|| ..|.:..:.:|.|
  Fly     5 CIPVSAKMSKAKKVLDEARETHNPEL---------DLADKGLSS--FEELP-GLFNMSNITRLTL 57

  Fly    68 SDNEIGRLPPDIQNFENLVELDVSRNDIPDIPDDIKHLQSLQVADFSSNPIPKLPSGFSQLKNLT 132
            |.|:|..:.|.|.|..||..|::|.|.:.::|..:..:..|::.:.|.|.:..||.||.....|.
  Fly    58 SHNKISVISPGIANLLNLEILNLSNNQLTELPVSLSSMPKLRILNVSINRLINLPRGFGAFPVLE 122

  Fly   133 VLGL--NDMSLTTLPADFGSLTQLESLELRENLLKHLPETISQLTKLKRLDLGDNEIEDLPPYLG 195
            ||.|  |:::...||.:|..:..|.:|.|.:|..:::|:.:.||..|:.|.|.||::.:||..:|
  Fly   123 VLDLSYNNLNEQVLPGNFFGMETLRALYLGDNDFEYIPKEVGQLKNLQILGLRDNDLLELPREVG 187

  Fly   196 YLPGLHELWLDHNQLQRLPPELGLLTKLTYLDVSENRLEELP 237
            .|..|.||.:.:|:||.||||:..|..|:  :.|..::||.|
  Fly   188 DLVRLRELHIQNNRLQVLPPEIAQLDLLS--NKSVMKMEENP 227

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scrib	NP_001163746.1	LRR_RI	13..283	CDD:238064	69/228 (30%)
		leucine-rich repeat	18..38	CDD:275380	3/20 (15%)
		LRR_8	37..95	CDD:290566	18/57 (32%)
		leucine-rich repeat	39..61	CDD:275380	5/21 (24%)
		leucine-rich repeat	62..84	CDD:275380	8/21 (38%)
		LRR_8	84..138	CDD:290566	17/55 (31%)
		leucine-rich repeat	85..107	CDD:275380	5/21 (24%)
		leucine-rich repeat	108..130	CDD:275380	7/21 (33%)
		LRR_8	129..187	CDD:290566	20/59 (34%)
		leucine-rich repeat	131..153	CDD:275380	8/23 (35%)
		leucine-rich repeat	154..176	CDD:275380	7/21 (33%)
		leucine-rich repeat	177..199	CDD:275380	9/21 (43%)
		LRR_8	198..256	CDD:290566	16/40 (40%)
		leucine-rich repeat	200..222	CDD:275380	11/21 (52%)
		leucine-rich repeat	223..245	CDD:275380	5/15 (33%)
		LRR_8	267..325	CDD:290566
		leucine-rich repeat	269..289	CDD:275380
		leucine-rich repeat	292..314	CDD:275380
		leucine-rich repeat	315..337	CDD:275380
		LRR_4	337..375	CDD:289563
		leucine-rich repeat	361..382	CDD:275380
		PDZ	728..816	CDD:214570
		PDZ_signaling	931..1016	CDD:238492
		PDZ	1239..1329	CDD:214570
		PDZ_signaling	1336..1425	CDD:238492
ics	NP_001285902.1	leucine-rich repeat	29..51	CDD:275380	5/33 (15%)
		leucine-rich repeat	52..84	CDD:275380	12/31 (39%)
		LRR_8	96..156	CDD:290566	19/59 (32%)
		leucine-rich repeat	98..120	CDD:275380	7/21 (33%)
		LRR	119..>222	CDD:227223	37/104 (36%)
		leucine-rich repeat	121..145	CDD:275380	8/23 (35%)
		leucine-rich repeat	146..168	CDD:275380	7/21 (33%)
		leucine-rich repeat	169..191	CDD:275380	9/21 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910