DRSC/TRiP Functional Genomics Resources

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Protein Alignment scrib and fnta-1

DIOPT Version :9

Sequence 1:NP_001163746.1 Gene:scrib / 44448 FlyBaseID:FBgn0263289 Length:2585 Species:Drosophila melanogaster
Sequence 2:NP_001380029.1 Gene:fnta-1 / 176840 WormBaseID:WBGene00019823 Length:328 Species:Caenorhabditis elegans


Alignment Length:298 Identity:61/298 - (20%)
Similarity:108/298 - (36%) Gaps:52/298 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly    67 LSDNEI--GRLPPDIQNFENLVELDVSRND--------IPDIPDDIKHLQSLQVADFSSNPIPKL 121
            :||::|  ..|..|..:::::..:..|:.:        ..|..|...:.:::.:.:..|:.:..|
 Worm     1 MSDSDIPSSTLYKDNVDWKDITPIYPSKEEEVAVKIAVTEDFTDAFAYFRAILIKNEKSDRVMAL 65

  Fly   122 PSGFSQLK--NLTVLGLNDMSLTTLPADFGSLTQLESLELR--ENLLKHLP-------------E 169
            .....:|.  |.||.....:.||.|..|.       ..|:|  .::::..|             |
 Worm    66 LEDCIRLNPANYTVWQYRRVCLTELGWDL-------KKEMRYLSDIIQESPKNYQVWHHRRFIVE 123

  Fly   170 TISQLTKLKRLDLGDNEIEDLPPYLGYLPGLHELWLDHNQLQRLPPELGLLTKLTYLDVSENRLE 234
            ||.:......|......|.|  ....|....|..|:.......|..||.....:..||   ||..
 Worm   124 TIGESAVNDELHFCSEVIRD--ENKNYHAWQHRQWVVRTFKVPLEKELTFALHMLLLD---NRNN 183

  Fly   235 ELPNEISGLVSLTD-----------LDLAQNLLEALPDGIAKLSRLTILKLDQNRLQRLNDTLGN 288
            ...|....|::|.|           ::||:..:|.:|:..:..:.|..| |..|.:...:|.:..
 Worm   184 SAYNYRYFLMTLYDKTEDASQLDIEINLAKKFIENIPNNESAWNYLAGL-LITNGVTSNSDVVSF 247

  Fly   289 CENMQELILTENFLSELPASIGQMTKLNNLNVDRNALE 326
            .|::.|....|.....|.|.|..| .|.|:...::|.|
 Worm   248 VEDLYETTPEEKRSPFLLAFIADM-MLENIENQKSAEE 284

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
scribNP_001163746.1 LRR_RI 13..283 CDD:238064 49/253 (19%)
leucine-rich repeat 18..38 CDD:275380
LRR_8 37..95 CDD:290566 6/37 (16%)
leucine-rich repeat 39..61 CDD:275380
leucine-rich repeat 62..84 CDD:275380 5/18 (28%)
LRR_8 84..138 CDD:290566 9/63 (14%)
leucine-rich repeat 85..107 CDD:275380 3/29 (10%)
leucine-rich repeat 108..130 CDD:275380 3/23 (13%)
LRR_8 129..187 CDD:290566 14/74 (19%)
leucine-rich repeat 131..153 CDD:275380 6/21 (29%)
leucine-rich repeat 154..176 CDD:275380 6/36 (17%)
leucine-rich repeat 177..199 CDD:275380 4/21 (19%)
LRR_8 198..256 CDD:290566 15/68 (22%)
leucine-rich repeat 200..222 CDD:275380 5/21 (24%)
leucine-rich repeat 223..245 CDD:275380 6/21 (29%)
LRR_8 267..325 CDD:290566 14/57 (25%)
leucine-rich repeat 269..289 CDD:275380 5/19 (26%)
leucine-rich repeat 292..314 CDD:275380 6/21 (29%)
leucine-rich repeat 315..337 CDD:275380 4/12 (33%)
LRR_4 337..375 CDD:289563
leucine-rich repeat 361..382 CDD:275380
PDZ 728..816 CDD:214570
PDZ_signaling 931..1016 CDD:238492
PDZ 1239..1329 CDD:214570
PDZ_signaling 1336..1425 CDD:238492
fnta-1NP_001380029.1 PLN02789 17..315 CDD:215423 56/282 (20%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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