Protein Alignment scrib and AgaP_AGAP004941

DIOPT Version :9

• Sequence 1: NP_001163746.1
• Gene: scrib / 44448
• FlyBaseID: FBgn0263289
• Length: 2585
• Species: Drosophila melanogaster
• Sequence 2: XP_315033.3
• Gene: AgaP_AGAP004941 / 1275747
• VectorBaseID: AGAP004941
• Length: 322
• Species: Anopheles gambiae
• Alignment Length: 296
• Identity: 75/296 - (25%)
• Similarity: 121/296 - (40%)
• Gaps: 65/296 - (21%)

  Fly   131 LTVLGLNDMSLTTLPADFGSLTQLESLELRENLLKHLPETI-----SQLTKLKRLDLGDNEIEDL 190
            |:.|.:.|..:.::||....|..||.||:.::.:    ||:     |:||.|:.|:|.||:|..|
Mosquito    29 LSFLTITDSRMKSVPATMAHLVVLEMLEISKSSI----ETVNLNLFSKLTHLRHLNLCDNKILFL 89

  Fly   191 PPYL-----GYLPGLHELWLDHNQLQRLPPELGLLTKLTYLDVSENRLEELPNEISGLVSLTDLD 250
              :|     |....|.:|:|..|             .||.:|:         ...|.:..|..||
Mosquito    90 --HLSDAAEGNFAQLRDLFLSGN-------------LLTTIDL---------RWFSNMKLLQTLD 130

  Fly   251 LAQNLLEALPDGIAKLSRLTILKLDQNRLQRLNDTLGNCENMQELILTENFLSELPASIG-QMTK 314
            |.:|.:..:...:...| |..|.|.:||::.||....|..::...:|:.|.|..||:.:. .|..
Mosquito   131 LHRNRIRRMQGALVSNS-LKFLDLSENRIETLNCCEWNITSLNRFMLSSNELVTLPSCLPLTMPN 194

  Fly   315 LNNLNVDRNALEYLPLEIGQCANLGVLSLRDNKLKKLPPELGNCTVLHVLDVSGNQLLYLPYSLV 379
            :..|.:.||||    .:.....||..|..                 |..||:|.|:|....:..|
Mosquito   195 VMYLILQRNAL----TDGNSWYNLFTLER-----------------LFQLDISYNRLTKAVFDNV 238

  Fly   380 NLQLKAVWLSENQSQPLLTFQPDTDAETGEQVLSCY 415
            :|.|..:.|..|..:.|..    ..|:.|..:|:.:
Mosquito   239 SLSLSILGLQNNNIKVLSV----PAADYGLNILASF 270

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scrib	NP_001163746.1	LRR_RI	13..283	CDD:238064	43/161 (27%)
		leucine-rich repeat	18..38	CDD:275380
		LRR_8	37..95	CDD:290566
		leucine-rich repeat	39..61	CDD:275380
		leucine-rich repeat	62..84	CDD:275380
		LRR_8	84..138	CDD:290566	2/6 (33%)
		leucine-rich repeat	85..107	CDD:275380
		leucine-rich repeat	108..130	CDD:275380
		LRR_8	129..187	CDD:290566	20/60 (33%)
		leucine-rich repeat	131..153	CDD:275380	6/21 (29%)
		leucine-rich repeat	154..176	CDD:275380	8/26 (31%)
		leucine-rich repeat	177..199	CDD:275380	9/26 (35%)
		LRR_8	198..256	CDD:290566	13/57 (23%)
		leucine-rich repeat	200..222	CDD:275380	4/21 (19%)
		leucine-rich repeat	223..245	CDD:275380	4/21 (19%)
		LRR_8	267..325	CDD:290566	18/58 (31%)
		leucine-rich repeat	269..289	CDD:275380	7/19 (37%)
		leucine-rich repeat	292..314	CDD:275380	6/22 (27%)
		leucine-rich repeat	315..337	CDD:275380	5/21 (24%)
		LRR_4	337..375	CDD:289563	9/37 (24%)
		leucine-rich repeat	361..382	CDD:275380	7/20 (35%)
		PDZ	728..816	CDD:214570
		PDZ_signaling	931..1016	CDD:238492
		PDZ	1239..1329	CDD:214570
		PDZ_signaling	1336..1425	CDD:238492
AgaP_AGAP004941	XP_315033.3	LRR_8	32..86	CDD:290566	19/57 (33%)
		leucine-rich repeat	52..75	CDD:275380	8/26 (31%)
		LRR_8	74..136	CDD:290566	23/85 (27%)
		leucine-rich repeat	76..101	CDD:275380	9/26 (35%)
		leucine-rich repeat	102..125	CDD:275380	8/44 (18%)
		leucine-rich repeat	126..147	CDD:275380	5/20 (25%)
		LRR_9	<128..225	CDD:258718	29/118 (25%)
		leucine-rich repeat	148..170	CDD:275380	8/21 (38%)
		leucine-rich repeat	171..194	CDD:275380	6/22 (27%)
		leucine-rich repeat	195..219	CDD:275380	8/27 (30%)
		leucine-rich repeat	220..241	CDD:275380	7/20 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910