Protein Alignment scrib and AgaP_AGAP000340

DIOPT Version :9

• Sequence 1: NP_001163746.1
• Gene: scrib / 44448
• FlyBaseID: FBgn0263289
• Length: 2585
• Species: Drosophila melanogaster
• Sequence 2: XP_310777.5
• Gene: AgaP_AGAP000340 / 1271920
• VectorBaseID: AGAP000340
• Length: 489
• Species: Anopheles gambiae
• Alignment Length: 284
• Identity: 89/284 - (31%)
• Similarity: 123/284 - (43%)
• Gaps: 48/284 - (16%)

  Fly    21 RHCSLPQVPEEILRYSRTLEELFLD-ANHIR-DLPKNFFRLHRLRKLGLSDNEIGRLPPDIQNFE 83
            |||:|..|          ...|||| ||.:| ||..|......|.........:|...|.:...:
Mosquito    97 RHCNLGSV----------AGGLFLDTANVLRVDLSHNRLTGDALTAAVFRGQYVGEDSPLLLQLD 151

  Fly    84 NLVELDVSRNDIPDIPDD-IKHLQSLQVADFSSNPIPKLPSG----FSQLKNLTVLGLNDMSLTT 143
               |||:..|.|..:.:| .:|:.||:....:.||:.:|..|    .:||.||..|.|:...||.
Mosquito   152 ---ELDLGANAIAHLQEDAFEHIVSLRELSLARNPLGRLAGGTARALAQLVNLEHLDLSYAELTE 213

  Fly   144 LPAD-FGSLTQLESLELRENLLKHLPETISQLTKLKRLDLGDNEIEDL---PPYLGYL------- 197
            |... ||.:..|..|.||.|.|..:||.:..|..|..|:|.:|.||.|   .| |.||
Mosquito   214 LDESVFGGMRSLHELNLRGNRLGAVPEALYPLAALHTLNLAENPIEVLSFAQP-LDYLFELNVSS 277

  Fly   198 -PGLHELWLDHNQLQRLPPELGLLTKLTYLDVSENRLEELPNEISGLVSLTDLDLAQNLLEAL-- 259
             |.||.:.:|.....|:...| |....|.|:|.:..:      :..|..|.:|||:|:.|:.|
Mosquito   278 MPVLHTVEVDSFAHVRMLRTL-LARNNTPLEVFDMTI------LHHLTDLRELDLSQSKLKHLHP 335

  Fly   260 PDG------IAKLSRLTILKLDQN 277
            |.|      .|.|:.|.||.|.:|
Mosquito   336 PTGSVALPPAAYLNVLEILLLHEN 359

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scrib	NP_001163746.1	LRR_RI	13..283	CDD:238064	89/284 (31%)
		leucine-rich repeat	18..38	CDD:275380	5/16 (31%)
		LRR_8	37..95	CDD:290566	17/59 (29%)
		leucine-rich repeat	39..61	CDD:275380	10/23 (43%)
		leucine-rich repeat	62..84	CDD:275380	3/21 (14%)
		LRR_8	84..138	CDD:290566	19/58 (33%)
		leucine-rich repeat	85..107	CDD:275380	7/22 (32%)
		leucine-rich repeat	108..130	CDD:275380	7/25 (28%)
		LRR_8	129..187	CDD:290566	22/58 (38%)
		leucine-rich repeat	131..153	CDD:275380	8/22 (36%)
		leucine-rich repeat	154..176	CDD:275380	9/21 (43%)
		leucine-rich repeat	177..199	CDD:275380	11/32 (34%)
		LRR_8	198..256	CDD:290566	16/57 (28%)
		leucine-rich repeat	200..222	CDD:275380	6/21 (29%)
		leucine-rich repeat	223..245	CDD:275380	4/21 (19%)
		LRR_8	267..325	CDD:290566	5/11 (45%)
		leucine-rich repeat	269..289	CDD:275380	5/9 (56%)
		leucine-rich repeat	292..314	CDD:275380
		leucine-rich repeat	315..337	CDD:275380
		LRR_4	337..375	CDD:289563
		leucine-rich repeat	361..382	CDD:275380
		PDZ	728..816	CDD:214570
		PDZ_signaling	931..1016	CDD:238492
		PDZ	1239..1329	CDD:214570
		PDZ_signaling	1336..1425	CDD:238492
AgaP_AGAP000340	XP_310777.5	leucine-rich repeat	43..63	CDD:275378
		leucine-rich repeat	71..91	CDD:275380
		leucine-rich repeat	92..114	CDD:275380	9/26 (35%)
		leucine-rich repeat	115..137	CDD:275380	5/21 (24%)
		leucine-rich repeat	138..173	CDD:275380	9/37 (24%)
		LRR_RI	<166..>330	CDD:238064	55/171 (32%)
		LRR_8	173..235	CDD:290566	22/61 (36%)
		leucine-rich repeat	174..200	CDD:275380	7/25 (28%)
		leucine-rich repeat	201..224	CDD:275380	8/22 (36%)
		LRR_8	223..303	CDD:290566	27/81 (33%)
		leucine-rich repeat	225..247	CDD:275380	9/21 (43%)
		leucine-rich repeat	248..294	CDD:275380	15/46 (33%)
		leucine-rich repeat	295..319	CDD:275380	6/30 (20%)
		TPKR_C2	359..>397	CDD:301599	1/1 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910