DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment scrib and AgaP_AGAP006993

DIOPT Version :9

Sequence 1:NP_001163746.1 Gene:scrib / 44448 FlyBaseID:FBgn0263289 Length:2585 Species:Drosophila melanogaster
Sequence 2:XP_308777.4 Gene:AgaP_AGAP006993 / 1270106 VectorBaseID:AGAP006993 Length:626 Species:Anopheles gambiae


Alignment Length:706 Identity:184/706 - (26%)
Similarity:287/706 - (40%) Gaps:151/706 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly    27 QVPEEILRYSRTLEELFLDANHIRDLPKNFFRLHRLR--------KLGLSDNEIGRLPPDIQNF- 82
            |:|.......:.|..:|    |.:|..::...|.|.|        .|.||...:..:|..:.|. 
Mosquito     6 QIPVRSRIRQQELNPVF----HFQDKQEDNQILTRARIKQALKSGVLNLSGKGLATVPEKVWNLS 66

  Fly    83 -----ENLVELDVSR-NDIPDIPDDIKHLQSLQVADFSSNPIPKLPSGFSQLKNLTVLGLNDMSL 141
                 |..|..|:.| ||    .:...:.:||...|.|||.:..:......|.:||||.|.|.:|
Mosquito    67 DSDENEKEVRYDLERTND----EESWWNQRSLTSLDLSSNTLTTISENIQNLVDLTVLNLQDNAL 127

  Fly   142 TTLPADFGSLTQLESLELRENLLKHLPETISQLTKLKRLDLGDNEIEDLPPYLGYLPGLHELWLD 206
            |:|||..|:||:|....:..|.|..|||:..||.:||.|:|..||..::.|.:..|..|..|.:.
Mosquito   128 TSLPAGIGALTKLTKFSVARNKLTELPESFFQLKELKHLNLSHNEFAEMNPNISDLIMLETLDVS 192

  Fly   207 HNQLQRLPPELGLLTKLTYLDVSENRLEELPNEISGLVSLTDLDLAQNLLEALPDGIAKLSRLTI 271
            .|.:..||..:|.|.:|..|.:|.|.|.||||:|..|..|..||||:|.|:.||..:.:|.||..
Mosquito   193 FNSINALPGGVGFLVRLQQLTLSNNHLTELPNDIVNLRKLQKLDLAKNDLKKLPPVMGELRRLEC 257

  Fly   272 LKLDQNRLQRLNDTLGNCENMQELILTENFLSELPASIGQMTKLNNLNVDRNALEYLPLEIGQCA 336
            ..:..|.:..|.|..| ||.::||.::.|::..||...               .|.||       
Mosquito   258 FYVQHNDIDELPDFTG-CEALKELHISNNYIKTLPGDF---------------CENLP------- 299

  Fly   337 NLGVLSLRDNKLKKLPPELGNCTVLHVLDVSGNQLLYLP------YSLVNLQLKAVWLSENQSQP 395
            .|.||.|||||::|||.|:.....|..||:|.|.:..||      ..||:||:        :..|
Mosquito   300 QLKVLDLRDNKIEKLPDEIALLASLTRLDLSNNTISSLPSCLSTLAHLVSLQV--------EGNP 356

  Fly   396 LLTFQPDTDAETGEQVLSCYLLPQQEYQPITPARDLESDSEPFEERE--------PSRTVVKFSE 452
            :.:.:.|        ::.|     ...:.:...|:.:...:|...::        .|..|||.| 
Mosquito   357 IRSIRRD--------IIQC-----GTQRILKTLRERDGTGKPDGGQKGVARAAASASTAVVKNS- 407

  Fly   453 EATQEKETPFVRQ---------------NTPHPKDLKA-KAQKLKVERSRNEEHANLVTLPEENG 501
             ...|...|.|.|               :.|....|.| :|....|:.|:|:    |..:|  :|
Mosquito   408 -LFTESTFPDVYQMRKGRALIVCSKALVDIPEAVFLDALEACVYNVDISKNK----LTAVP--SG 465

  Fly   502 -TKLAETPTETRTIANNHQQQPHPVQQ----PIVGVNSKQ----PVVVGVVTPTTTTVAPTGVQG 557
             |.|:...||.....|..|..|....|    ..:.:::.|    |.|||::    .|:....|  
Mosquito   466 ITHLSSLLTELNVSFNLLQTVPAFFSQFDKISYLNLSNNQMTDLPEVVGLL----VTLRELNV-- 524

  Fly   558 GSEGASSTANNVKAATAAV--VAELAATVGGSDEVQDDDEQEDEFESDRRVGFQVEGEDDDFYKR 620
                   .:|.:|.....|  :..|...:...:::::.|..|....:.:|:. .::..:::....
Mosquito   525 -------ISNQLKRIPDCVYELRGLEILLASGNQIEEIDATESGLGALKRLA-TLDLANNNIKHV 581

  Fly   621 PPKLHRRDTPHHLKNKRVQHLTDKQASEILANALASQERNDTTPQHSLSGKVTSPI 676
            ||.|..      |||     :|   ..|::.|:...       |:|.:..|.|..|
Mosquito   582 PPVLGT------LKN-----IT---TLELIGNSFRQ-------PRHQILEKGTESI 616

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
scribNP_001163746.1 LRR_RI 13..283 CDD:238064 88/270 (33%)
leucine-rich repeat 18..38 CDD:275380 2/10 (20%)
LRR_8 37..95 CDD:290566 17/72 (24%)
leucine-rich repeat 39..61 CDD:275380 5/21 (24%)
leucine-rich repeat 62..84 CDD:275380 6/35 (17%)
LRR_8 84..138 CDD:290566 17/54 (31%)
leucine-rich repeat 85..107 CDD:275380 5/22 (23%)
leucine-rich repeat 108..130 CDD:275380 6/21 (29%)
LRR_8 129..187 CDD:290566 27/57 (47%)
leucine-rich repeat 131..153 CDD:275380 13/21 (62%)
leucine-rich repeat 154..176 CDD:275380 8/21 (38%)
leucine-rich repeat 177..199 CDD:275380 8/21 (38%)
LRR_8 198..256 CDD:290566 24/57 (42%)
leucine-rich repeat 200..222 CDD:275380 7/21 (33%)
leucine-rich repeat 223..245 CDD:275380 11/21 (52%)
LRR_8 267..325 CDD:290566 13/57 (23%)
leucine-rich repeat 269..289 CDD:275380 5/19 (26%)
leucine-rich repeat 292..314 CDD:275380 5/21 (24%)
leucine-rich repeat 315..337 CDD:275380 3/21 (14%)
LRR_4 337..375 CDD:289563 17/37 (46%)
leucine-rich repeat 361..382 CDD:275380 9/26 (35%)
PDZ 728..816 CDD:214570
PDZ_signaling 931..1016 CDD:238492
PDZ 1239..1329 CDD:214570
PDZ_signaling 1336..1425 CDD:238492
AgaP_AGAP006993XP_308777.4 LRR_RI 92..335 CDD:238064 98/265 (37%)
LRR_8 92..171 CDD:290566 33/78 (42%)
leucine-rich repeat 94..116 CDD:275380 6/21 (29%)
leucine-rich repeat 117..139 CDD:275380 13/21 (62%)
leucine-rich repeat 140..162 CDD:275380 8/21 (38%)
LRR 157..622 CDD:227223 137/547 (25%)
leucine-rich repeat 163..185 CDD:275380 8/21 (38%)
leucine-rich repeat 186..208 CDD:275380 7/21 (33%)
leucine-rich repeat 209..231 CDD:275380 11/21 (52%)
leucine-rich repeat 232..254 CDD:275380 10/21 (48%)
leucine-rich repeat 255..276 CDD:275380 6/21 (29%)
leucine-rich repeat 277..300 CDD:275380 8/44 (18%)
leucine-rich repeat 324..346 CDD:275380 7/21 (33%)
leucine-rich repeat 347..471 CDD:275380 30/152 (20%)
leucine-rich repeat 472..495 CDD:275380 6/22 (27%)
leucine-rich repeat 519..541 CDD:275380 4/30 (13%)
leucine-rich repeat 542..568 CDD:275380 3/25 (12%)
leucine-rich repeat 569..590 CDD:275380 4/27 (15%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

Return to query results.
Submit another query.