Protein Alignment scrib and si:dkey-182i3.11

DIOPT Version :9

• Sequence 1: NP_001163746.1
• Gene: scrib / 44448
• FlyBaseID: FBgn0263289
• Length: 2585
• Species: Drosophila melanogaster
• Sequence 2: XP_021322095.1
• Gene: si:dkey-182i3.11 / 100334238
• ZFINID: ZDB-GENE-121214-258
• Length: 710
• Species: Danio rerio
• Alignment Length: 463
• Identity: 141/463 - (30%)
• Similarity: 207/463 - (44%)
• Gaps: 41/463 - (8%)

  Fly    39 LEELFLDANHIRDLPKNFFR-LHRLRKLGLSDNEIGRLPPDI-QNFENLVELDVSRNDIPDIPDD 101
            |.:|:|..|.::.:....|: ...|..|.|..|.:..:|..: |...||..|.:.:|||..|||:
Zfish   225 LAKLYLSKNKLKSVGNGSFKGATGLNHLDLGLNGLAGIPTIVLQETSNLTSLYLQKNDITSIPDN 289

  Fly   102 I-KHLQSLQVADFSSNPIPKLPSG-FSQLKNLTVLGLNDMSLTTLPAD-FGSLTQLESLELRENL 163
            : ..:.||:..|.|.|.:..:.:| |..|..|..|.|:...|.||... |..|.:||:|.|..|.
Zfish   290 VFSEILSLKHLDLSYNGLVSISNGSFRSLSQLVYLDLSFNQLQTLTQHVFEDLGKLENLNLYHNK 354

  Fly   164 LKHLPETI-SQLTKLKRLDLGDNEIEDLPPYLGY-LPGLHELWLDHNQLQRLPPE-LGLLTKLTY 225
            |..||..: ..||.||.|.|..|.|..:||.|.: |..|.:|.||:|.:.:|... ...|.:|..
Zfish   355 LTSLPNNMFKNLTMLKELQLDSNNISVIPPDLFHPLSALKDLQLDNNHISKLHSHTFKKLRQLKQ 419

  Fly   226 LDVSENRLEELPNEISGLVSLTDLDLAQNLLEALPD-GIAKLSRLTILKLDQNRLQRL-NDTLGN 288
            ||:|.|.|.::||.:.. .:|.:|:|..|.:..:.. ....|.||..|||..|.|.:| .:.|.|
Zfish   420 LDISSNDLTKIPNHLFH-KNLKELNLENNHISFISKFSFKNLHRLQSLKLSHNNLSKLYRELLTN 483

  Fly   289 CENMQELILTENFLSELPASIGQMTKLNNLNV---DRNALEY-LPLEIGQCANLGVLSLRDNKLK 349
            ...::||:|.||.:..:|  :|....|.||.|   ..|.:.: ||......:.|..|.|..|.|.
Zfish   484 LTRLRELLLNENQIETIP--VGFFKGLENLRVLDLSNNKMHFILPDAFNDLSALKDLDLSFNFLH 546

  Fly   350 KLPPE----LGNCTVLHVLDVSGNQLLYLPYSLVN--LQLKAVWLSENQSQPLLTFQPDTDAETG 408
            .||.:    |.|.|.||   :..|:|.|||..|.:  :.|:.:.|..|..|.:...|.:...:..
Zfish   547 NLPEDIFASLRNLTKLH---LQNNKLRYLPSRLFSALVGLEELHLDRNYIQRIHPTQFEGLVKLH 608

  Fly   409 EQVLSCYLLPQQEYQPITPARDLES---DSEPFEEREPSRTVV------KFSEEATQEKETPFVR 464
            |..:....|...|...:.|.|.|:.   |..|::    ..|||      .|:......|.||...
Zfish   609 ELDMKSNQLRSMEDGTLMPLRKLKRIHLDGNPWD----CSTVVILYISQWFNNNTQLVKTTPMCS 669

  Fly   465 --QNTPHP 470
              ||..:|
Zfish   670 SGQNLSNP 677

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scrib	NP_001163746.1	LRR_RI	13..283	CDD:238064	84/253 (33%)
		leucine-rich repeat	18..38	CDD:275380
		LRR_8	37..95	CDD:290566	15/57 (26%)
		leucine-rich repeat	39..61	CDD:275380	5/22 (23%)
		leucine-rich repeat	62..84	CDD:275380	6/22 (27%)
		LRR_8	84..138	CDD:290566	20/55 (36%)
		leucine-rich repeat	85..107	CDD:275380	8/22 (36%)
		leucine-rich repeat	108..130	CDD:275380	7/22 (32%)
		LRR_8	129..187	CDD:290566	23/59 (39%)
		leucine-rich repeat	131..153	CDD:275380	8/22 (36%)
		leucine-rich repeat	154..176	CDD:275380	9/22 (41%)
		leucine-rich repeat	177..199	CDD:275380	10/22 (45%)
		LRR_8	198..256	CDD:290566	19/58 (33%)
		leucine-rich repeat	200..222	CDD:275380	7/22 (32%)
		leucine-rich repeat	223..245	CDD:275380	8/21 (38%)
		LRR_8	267..325	CDD:290566	22/61 (36%)
		leucine-rich repeat	269..289	CDD:275380	8/20 (40%)
		leucine-rich repeat	292..314	CDD:275380	7/21 (33%)
		leucine-rich repeat	315..337	CDD:275380	7/25 (28%)
		LRR_4	337..375	CDD:289563	15/41 (37%)
		leucine-rich repeat	361..382	CDD:275380	8/22 (36%)
		PDZ	728..816	CDD:214570
		PDZ_signaling	931..1016	CDD:238492
		PDZ	1239..1329	CDD:214570
		PDZ_signaling	1336..1425	CDD:238492
si:dkey-182i3.11	XP_021322095.1	PLN00113	97..>617	CDD:331614	124/397 (31%)
		leucine-rich repeat	129..152	CDD:275380
		leucine-rich repeat	153..176	CDD:275380
		leucine-rich repeat	177..200	CDD:275380
		leucine-rich repeat	201..224	CDD:275380
		leucine-rich repeat	225..248	CDD:275380	5/22 (23%)
		leucine-rich repeat	249..272	CDD:275380	6/22 (27%)
		leucine-rich repeat	273..296	CDD:275380	8/22 (36%)
		leucine-rich repeat	297..320	CDD:275380	7/22 (32%)
		leucine-rich repeat	321..344	CDD:275380	8/22 (36%)
		leucine-rich repeat	345..368	CDD:275380	9/22 (41%)
		leucine-rich repeat	369..392	CDD:275380	10/22 (45%)
		leucine-rich repeat	393..438	CDD:275380	15/45 (33%)
		leucine-rich repeat	417..436	CDD:275380	8/18 (44%)
		leucine-rich repeat	439..462	CDD:275380	5/22 (23%)
		leucine-rich repeat	463..486	CDD:275380	9/22 (41%)
		leucine-rich repeat	487..510	CDD:275380	8/24 (33%)
		leucine-rich repeat	511..534	CDD:275380	5/22 (23%)
		leucine-rich repeat	535..558	CDD:275380	8/22 (36%)
		leucine-rich repeat	559..582	CDD:275380	9/25 (36%)
		leucine-rich repeat	583..606	CDD:275380	5/22 (23%)
		leucine-rich repeat	607..628	CDD:275380	3/20 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910