DRSC/TRiP Functional Genomics Resources

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Protein Alignment scrib and si:zfos-323e3.4

DIOPT Version :9

Sequence 1:NP_001163746.1 Gene:scrib / 44448 FlyBaseID:FBgn0263289 Length:2585 Species:Drosophila melanogaster
Sequence 2:XP_005168747.1 Gene:si:zfos-323e3.4 / 100333177 ZFINID:ZDB-GENE-120215-44 Length:791 Species:Danio rerio


Alignment Length:338 Identity:102/338 - (30%)
Similarity:152/338 - (44%) Gaps:67/338 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly    48 HIRDLPKNFFRLHRLRKLGLSDNEIGRLPPDIQNFENLVELDVSRNDIPDIPDDIKHLQSLQVAD 112
            |:||         :|:.|.::......||..:...:||.||.:| .|:  ..|.::.|::|:|..
Zfish   484 HLRD---------QLKVLRVATESQELLPLWMYTLQNLEELHLS-GDL--TLDSLRELKNLRVLT 536

  Fly   113 FSSNPIPKLPSG----------------------FSQLK---NLTVLGLNDMSLTTLPADFGSLT 152
            .... :.|:|.|                      ||.||   .|..|.|....|..:|:...||:
Zfish   537 LRCK-LTKIPPGVMDVSQQLLRLCVHNEGTRLQAFSSLKKLVRLAALELTGCGLERIPSAVFSLS 600

  Fly   153 QLESLELRENLLKHLPETIS--QLTKLKRLDLGDNEIEDLPPYLGYLPGLHELWLDHNQLQRLPP 215
            .|:.|:||||.|..:.|.:|  ...:|..|.||.|.|..:|.::..|..|..|.:..|.|.||||
Zfish   601 HLQELDLRENRLMAVEEILSLQHCRRLATLRLGHNRISCIPEHISRLRALETLDVSWNSLCRLPP 665

  Fly   216 ELGLLTKLTYLDVSENRLEELPNEISGLVSLTDLDLAQNLLEALPDGIAKLSRLTILKLDQNRLQ 280
            .|....:|.:||:|.|:|..||:||..|..|..|.:|.|.||:||:.:....||.:|.|..|.:.
Zfish   666 RLCYCPRLRHLDLSHNQLVSLPSEIGVLQGLQFLSVAFNALESLPEELFSCRRLRVLALGNNSIT 730

  Fly   281 RLNDTLGNCENMQELILTENFLSELPASIGQMTKLNNLNVDRNALEYLPLEIGQCANL---GVLS 342
            .|:..:||                       :.:|..|.:..|.||.||:||..|..|   ||: 
Zfish   731 ALSPRVGN-----------------------LAQLVRLELKGNRLEGLPVEIADCPALQLTGVI- 771

  Fly   343 LRDNKLKKLPPEL 355
            :.|:.::.||.||
Zfish   772 VEDSLMELLPAEL 784

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
scribNP_001163746.1 LRR_RI 13..283 CDD:238064 81/261 (31%)
leucine-rich repeat 18..38 CDD:275380
LRR_8 37..95 CDD:290566 12/46 (26%)
leucine-rich repeat 39..61 CDD:275380 3/12 (25%)
leucine-rich repeat 62..84 CDD:275380 4/21 (19%)
LRR_8 84..138 CDD:290566 20/78 (26%)
leucine-rich repeat 85..107 CDD:275380 7/21 (33%)
leucine-rich repeat 108..130 CDD:275380 9/46 (20%)
LRR_8 129..187 CDD:290566 22/62 (35%)
leucine-rich repeat 131..153 CDD:275380 7/21 (33%)
leucine-rich repeat 154..176 CDD:275380 9/23 (39%)
leucine-rich repeat 177..199 CDD:275380 8/21 (38%)
LRR_8 198..256 CDD:290566 24/57 (42%)
leucine-rich repeat 200..222 CDD:275380 9/21 (43%)
leucine-rich repeat 223..245 CDD:275380 11/21 (52%)
LRR_8 267..325 CDD:290566 11/57 (19%)
leucine-rich repeat 269..289 CDD:275380 6/19 (32%)
leucine-rich repeat 292..314 CDD:275380 0/21 (0%)
leucine-rich repeat 315..337 CDD:275380 10/21 (48%)
LRR_4 337..375 CDD:289563 8/22 (36%)
leucine-rich repeat 361..382 CDD:275380
PDZ 728..816 CDD:214570
PDZ_signaling 931..1016 CDD:238492
PDZ 1239..1329 CDD:214570
PDZ_signaling 1336..1425 CDD:238492
si:zfos-323e3.4XP_005168747.1 Pannexin_like 1..334 CDD:289311
leucine-rich repeat 465..488 CDD:275380 3/12 (25%)
leucine-rich repeat 489..508 CDD:275380 4/18 (22%)
leucine-rich repeat 512..531 CDD:275380 7/21 (33%)
leucine-rich repeat 532..575 CDD:275380 8/43 (19%)
LRR_RI <573..752 CDD:238064 65/201 (32%)
leucine-rich repeat 576..601 CDD:275380 7/24 (29%)
LRR_8 578..637 CDD:290566 21/58 (36%)
leucine-rich repeat 602..626 CDD:275380 9/23 (39%)
LRR_8 625..683 CDD:290566 22/57 (39%)
leucine-rich repeat 627..649 CDD:275380 8/21 (38%)
leucine-rich repeat 650..672 CDD:275380 9/21 (43%)
LRR_8 671..752 CDD:290566 30/103 (29%)
leucine-rich repeat 673..695 CDD:275380 11/21 (52%)
leucine-rich repeat 696..718 CDD:275380 8/21 (38%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.910

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