Protein Alignment HDAC3 and HOS1

DIOPT Version :9

• Sequence 1: NP_651978.2
• Gene: HDAC3 / 44446
• FlyBaseID: FBgn0025825
• Length: 438
• Species: Drosophila melanogaster
• Sequence 2: NP_015393.1
• Gene: HOS1 / 856181
• SGDID: S000006272
• Length: 470
• Species: Saccharomyces cerevisiae
• Alignment Length: 478
• Identity: 128/478 - (26%)
• Similarity: 187/478 - (39%)
• Gaps: 152/478 - (31%)

  Fly    28 QRLAVTHSLVMNYGL--HKKMKIYRPYKASAQDMLRFHSDEYIAYL------------------- 71
            |:..:|:||:..|.|  |....:..|| |...|:|.|||..||.||
Yeast    25 QKSQLTYSLINAYDLLQHFDEVLTFPY-ARKDDLLEFHSKSYIDYLINGRFNKMMAQDVNNPMVE 88

  Fly    72 -----------------------------------------QQVTPQNIQC--NSVAYTK----- 88
                                                     .|....|:.|  ||...|.
Yeast    89 SKWSELSELADNWNEKIDYNPSQDLQRFTTRENLYNYYLNHSQALENNMDCINNSEVPTNDKPTD 153

  Fly    89 -YLAH-----FSVGEDCPVFDGLFDFCAMYTGASLEGAQKLNHNHSDICINWSGGLHHAKKFEAS 147
             |:.:     :::..|||:|..|..:|.:.|||:|.....|:.....|.|||.||.|||.|..||
Yeast   154 TYILNSETKQYNLEGDCPIFSYLPMYCQVITGATLNLLDHLSPTERLIGINWDGGRHHAFKQRAS 218

  Fly   148 GFCYVNDIVIGILELLKYH-PRVLYIDIDVHHGDGVQEAFYLTDRVMTASFHKYGNYFFPGTGDM 211
            ||||:||:|:.|..|.|.. .::.|:|.|:||||||::||..:.::.|.|.|.|...||||||.:
Yeast   219 GFCYINDVVLLIQRLRKAKLNKITYVDFDLHHGDGVEKAFQYSKQIQTISVHLYEPGFFPGTGSL 283

  Fly   212 YEIGAESGRYYSVNVPLKEGIDDQSYFQVFKPIISAIMDFYRPTAIVLQCGADSLAGDRLGCFSL 276
            .:...:..   .||:|||.|.||.....:...|::.:::.:.|.|::::||.|.|.|||...:.|
Yeast   284 SDSRKDKN---VVNIPLKHGCDDNYLELIASKIVNPLIERHEPEALIIECGGDGLLGDRFNEWQL 345

  Fly   277 STKGHGECVKFVKELNV-------PTLVVGGGGYTLRNVARCWTHETSLLVDQDIENDLPATEYY 334
            :.:|....:     :|:       ...::|||||                      |||..:.:|
Yeast   346 TIRGLSRII-----INIMKSYPRAHIFLLGGGGY----------------------NDLLMSRFY 383

  Fly   335 DFFAPDFTLHPEINSRQDNANSKQYLELIVKHVYENLKMCQHSPSVQMVQTPPDVDLEELRSNRE 399
                                   .||...|...:.||: |..:.|.|:  .|.||
Yeast   384 -----------------------TYLTWCVTKQFSNLR-CGDNNSFQI--DPFDV---------- 412

  Fly   400 EASDPDVRISVADEDKLVDAKNE 422
              .|.|.......|..||:..||
Yeast   413 --CDGDDSEQFIREHDLVEMYNE 433

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HDAC3	NP_651978.2	HDAC3	4..388	CDD:212529	119/442 (27%)
HOS1	NP_015393.1	HDAC_Hos1	5..390	CDD:212543	112/418 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0123
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810