Protein Alignment HDAC3 and HOS3

DIOPT Version :9

• Sequence 1: NP_651978.2
• Gene: HDAC3 / 44446
• FlyBaseID: FBgn0025825
• Length: 438
• Species: Drosophila melanogaster
• Sequence 2: NP_015209.1
• Gene: HOS3 / 855987
• SGDID: S000006037
• Length: 697
• Species: Saccharomyces cerevisiae
• Alignment Length: 472
• Identity: 83/472 - (17%)
• Similarity: 143/472 - (30%)
• Gaps: 204/472 - (43%)

  Fly   110 AMYTGASLEGAQKLNHNHSDICINWSGGLHHAKKFEASGFCYVNDIVIGILELLKYH------PR 168
            :::.|.|.|...    |.:.:.|...|  ||......||||.:|:..:.|    :|.      ..
Yeast   172 SIFKGPSAEHIS----NRAFVAIRPPG--HHCHYGTPSGFCLLNNAHVAI----EYAYDTYNVTH 226

  Fly   169 VLYIDIDVHHGDGVQE------AFYLTDRVMTASFHKYGNYF--FPGTG--DMYEIGA---ESGR 220
            |:.:|.|:|||||.|:      .|...:....:|:..:|..|  ||..|  .|::|.:   |||
Yeast   227 VVVLDFDLHHGDGTQDICWKRAGFKPEEEPEDSSYDDFGKKFAEFPKVGYFSMHDINSFPTESG- 290

  Fly   221 YYSVNVPLKEGIDDQS----------------------------YFQVFKPIISAIMDFYRPT-- 255
                 ...||.|.:.|                            |...::.:.:...:|:|..
Yeast   291 -----FATKENIKNASTCIMNSHDLNIWNIHLSKWTTEEEFNVLYRTKYRTLFAKADEFFRSAKL 350

  Fly   256 -----------AIVLQCGADSLAGDRLGCFSLSTKGHGECVKFVKELNVPT-------------- 295
                       .:|:..|.|:...::     .|.:.|        .:||||
Yeast   351 EMNQQGRPFKGLVVISAGFDASEFEQ-----TSMQRH--------SVNVPTSFYTTFTKDALKLA 402

  Fly   296 --------LVVGGGGYT------------------------------------------------ 304
                    |.:..|||:
Yeast   403 QMHCHGKVLSLMEGGYSDKAICSGVFAHLIGLQNQDWVKEWGSEQVVKEIVRGCKPAWKPYKTKR 467

  Fly   305 LRNVARCWTHETSLL-----------VDQDIENDLPATEYYDFFAPDFTLHPE---------INS 349
            .::|.|.|..|...|           :.:|..|..|:....     ..|:.|.         |.|
Yeast   468 AKDVIRIWAEEVIRLGRAMIPEFDDIIFKDAVNSAPSNSLL-----KATVEPASTSTIAQRIIRS 527

  Fly   350 RQDNANSKQYLELIVKHVYENLKMCQHSPSVQMVQTPPDVDLEELRSNREEASDPDVRISVADED 414
            .:.||:.:       |.::||..........:.:::  |..:::|.||...|           |.
Yeast   528 HRSNASPE-------KELHENKPRSTEKQEQREIRS--DTKVKQLSSNNRAA-----------ET 572

  Fly   415 KLVDAKNEFYDGDQDQD 431
            ::...:.||...|:|::
Yeast   573 QIPFLQQEFSSEDEDEE 589

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HDAC3	NP_651978.2	HDAC3	4..388	CDD:212529	73/427 (17%)
HOS3	NP_015209.1	HDAC_Hos3	47..435	CDD:212522	56/291 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0123
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810