Protein Alignment HDAC3 and Hdac2

DIOPT Version :9

• Sequence 1: NP_651978.2
• Gene: HDAC3 / 44446
• FlyBaseID: FBgn0025825
• Length: 438
• Species: Drosophila melanogaster
• Sequence 2: NP_445899.1
• Gene: Hdac2 / 84577
• RGDID: 619976
• Length: 488
• Species: Rattus norvegicus
• Alignment Length: 428
• Identity: 246/428 - (57%)
• Similarity: 332/428 - (77%)
• Gaps: 12/428 - (2%)

  Fly     4 RRVSYFYNADVGNFHYGAGHPMKPQRLAVTHSLVMNYGLHKKMKIYRPYKASAQDMLRFHSDEYI 68
            ::|.|:|:.|:||::||.||||||.|:.:||:|::||||::||:||||:||:|::|.::||||||
  Rat    10 KKVCYYYDGDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATAEEMTKYHSDEYI 74

  Fly    69 AYLQQVTPQNIQCNSVAYTKYLAHFSVGEDCPVFDGLFDFCAMYTGASLEGAQKLNHNHSDICIN 133
            .:|:.:.|.|:.    .|:|.:..|:||||||||||||:||.:.||.|:.||.|||...:|:.:|
  Rat    75 KFLRSIRPDNMS----EYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVAGAVKLNRQQTDMAVN 135

  Fly   134 WSGGLHHAKKFEASGFCYVNDIVIGILELLKYHPRVLYIDIDVHHGDGVQEAFYLTDRVMTASFH 198
            |:||||||||.||||||||||||:.:|||||||.||||||||:||||||:||||.||||||.|||
  Rat   136 WAGGLHHAKKSEASGFCYVNDIVLAVLELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFH 200

  Fly   199 KYGNYFFPGTGDMYEIGAESGRYYSVNVPLKEGIDDQSYFQVFKPIISAIMDFYRPTAIVLQCGA 263
            |||.| ||||||:.:|||..|:||:||.|:::||||:||.|:||||||.:|:.|:|:|:||||||
  Rat   201 KYGEY-FPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYGQIFKPIISKVMEMYQPSAVVLQCGA 264

  Fly   264 DSLAGDRLGCFSLSTKGHGECVKFVKELNVPTLVVGGGGYTLRNVARCWTHETSLLVDQDIENDL 328
            |||:|||||||:|:.|||.:||:.||..|:|.|::||||||:||||||||:||::.:|.:|.|:|
  Rat   265 DSLSGDRLGCFNLTVKGHAKCVEVVKTFNLPLLMLGGGGYTIRNVARCWTYETAVALDCEIPNEL 329

  Fly   329 PATEYYDFFAPDFTLH--PEINSRQDNANSKQYLELIVKHVYENLKMCQHSPSVQMVQTPPDVDL 391
            |..:|:::|.|||.||  |   |...|.|:.:|:|.|.:.::|||:|..|:|.|||...|.|...
  Rat   330 PYNDYFEYFGPDFKLHISP---SNMTNQNTPEYMEKIKQRLFENLRMLPHAPGVQMQAIPEDAVH 391

  Fly   392 EELRSNREEASDPDVRISVADEDKLVDAKNEFYDGDQD 429
            |:  |..|:..|||.|||:...||.:....||.|.:.:
  Rat   392 ED--SGDEDGEDPDKRISIRASDKRIACDEEFSDSEDE 427

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HDAC3	NP_651978.2	HDAC3	4..388	CDD:212529	231/385 (60%)
Hdac2	NP_445899.1	PTZ00063	9..398	CDD:240251	234/397 (59%)
		HDAC2	9..374	CDD:212535	224/371 (60%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0123
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000617
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100248
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.710