Protein Alignment HDAC3 and hdac4

DIOPT Version :9

• Sequence 1: NP_651978.2
• Gene: HDAC3 / 44446
• FlyBaseID: FBgn0025825
• Length: 438
• Species: Drosophila melanogaster
• Sequence 2: XP_005172586.1
• Gene: hdac4 / 568877
• ZFINID: ZDB-GENE-061013-95
• Length: 1052
• Species: Danio rerio
• Alignment Length: 463
• Identity: 113/463 - (24%)
• Similarity: 187/463 - (40%)
• Gaps: 110/463 - (23%)

  Fly    23 HPMKPQRLAVTHSLVMNYGLHKKMKIYRPYKASAQDMLRFHSDEYIAY-----LQQ-----VTPQ 77
            ||....|:....|.:...||..:.:..|..||:.:::...||:.::..     |:|     |||.
Zfish   649 HPEHAGRIQSIWSRLQETGLRGQCECIRGRKATLEELQTVHSEAHVLLYGTNPLRQKLDSSVTPM 713

  Fly    78 --NIQCNSV----------AYTKYLAHFSVGEDCPVFDGLFDFCAMYTGASLEGAQKLNHNHSDI 130
              .:.|..:          .::...|..:||.   |.|.:|...
Zfish   714 FVRLPCGGIGVDSDTIWNEVHSSSAARLAVGS---VVDLVFKVA--------------------- 754

  Fly   131 CINWSGGL-----------HHAKKFEASGFCYVNDIVIGILELLKYH---PRVLYIDIDVHHGDG 181
                ||.|           |||::....||||.|.:.|. .:||:..   .::|.:|.|||||:|
Zfish   755 ----SGELRNGFAVVRPPGHHAEESTPMGFCYFNSVAIA-AKLLQQRLNVSKILIVDWDVHHGNG 814

  Fly   182 VQEAFYLTDRVMTASFHKY--GNYFFPGTGDMYEIGAESGRYYSVNVPLKEGID----DQSYFQV 240
            .|:|||....|:..|.|:|  || ||||:|...|:|...|..::||:....|::    |..|...
Zfish   815 TQQAFYSDPNVLYLSLHRYDDGN-FFPGSGAPDEVGIGPGVGFNVNMAFTGGLEPPMGDADYLAA 878

  Fly   241 FKPIISAIMDFYRPTAIVLQCGADSLAG--DRLGCFSLSTKGHGECVKFVKELNVPTLVVG-GGG 302
            |:.::..|.:.:.|..:::..|.|::.|  ..||.:.|:.|..|...|.:..|....||:. .||
Zfish   879 FRSVVMPIANEFSPDVVLVSSGFDAVEGHPPPLGGYKLTAKCFGYLTKQLMGLAGGRLVLALEGG 943

  Fly   303 YTLRNVARCWTHE--TSLLVDQDIENDLPATEYYDFFAPDFTLHPEINSRQDNANSKQYLELIVK 365
            :.|  .|.|...|  .|.|:..:::   |..|             :|..::.|||:.|.:|.:::
Zfish   944 HDL--TAICDASEACVSALLGNELD---PIPE-------------DILQQRPNANAIQSMEKVLE 990

  Fly   366 HVYENLKMCQHSPSVQMVQTPPDVDLEEL-RSNREEASDPDVRISVADEDKLVDAKNEFYDGDQD 429
            ...:..:..|.|.|..      ...|.|. |...|||.......|::..:|        :.|.:.
Zfish   991 VQSKYWRSLQRSVSTL------GYSLREAQRCENEEAETVTAMASLSVANK--------HMGKRP 1041

  Fly   430 QDKPDSAE 437
            :::|...|
Zfish  1042 EEEPMEEE 1049

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HDAC3	NP_651978.2	HDAC3	4..388	CDD:212529	102/411 (25%)
hdac4	XP_005172586.1	ClassIIa_HDAC4_Gln-rich-N	62..151	CDD:197398
		PKK	68..187	CDD:289257
		Arginase_HDAC	623..1025	CDD:302587	108/429 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910