Protein Alignment HDAC3 and hdac3

DIOPT Version :9

• Sequence 1: NP_651978.2
• Gene: HDAC3 / 44446
• FlyBaseID: FBgn0025825
• Length: 438
• Species: Drosophila melanogaster
• Sequence 2: NP_001016883.1
• Gene: hdac3 / 549637
• XenbaseID: XB-GENE-481106
• Length: 428
• Species: Xenopus tropicalis
• Alignment Length: 434
• Identity: 286/434 - (65%)
• Similarity: 355/434 - (81%)
• Gaps: 9/434 - (2%)

  Fly     4 RRVSYFYNADVGNFHYGAGHPMKPQRLAVTHSLVMNYGLHKKMKIYRPYKASAQDMLRFHSDEYI 68
            :.|:|||:.||||||||.||||||.||::|||||::|||:|||.:::||:||..||.||||::||
 Frog     3 KTVAYFYDPDVGNFHYGTGHPMKPHRLSLTHSLVLHYGLYKKMIVFKPYQASQHDMCRFHSEDYI 67

  Fly    69 AYLQQVTPQNIQCNSVAYTKYLAHFSVGEDCPVFDGLFDFCAMYTGASLEGAQKLNHNHSDICIN 133
            .:||:|:|.|:|    .:||.|..|:||:|||||.|||:||:.||||||:||.:||:...||.||
 Frog    68 DFLQRVSPNNMQ----GFTKSLNAFNVGDDCPVFPGLFEFCSRYTGASLQGATQLNNKICDIAIN 128

  Fly   134 WSGGLHHAKKFEASGFCYVNDIVIGILELLKYHPRVLYIDIDVHHGDGVQEAFYLTDRVMTASFH 198
            |:||||||||||||||||||||||||||||||||||||:|||:||||||||||||||||||.|||
 Frog   129 WAGGLHHAKKFEASGFCYVNDIVIGILELLKYHPRVLYVDIDIHHGDGVQEAFYLTDRVMTVSFH 193

  Fly   199 KYGNYFFPGTGDMYEIGAESGRYYSVNVPLKEGIDDQSYFQVFKPIISAIMDFYRPTAIVLQCGA 263
            |||||||||||||||:||||||||.:||||::|||||||..:|:|:|..::|||:||.|||||||
 Frog   194 KYGNYFFPGTGDMYEVGAESGRYYCLNVPLRDGIDDQSYRHLFQPVIKQVIDFYQPTCIVLQCGA 258

  Fly   264 DSLAGDRLGCFSLSTKGHGECVKFVKELNVPTLVVGGGGYTLRNVARCWTHETSLLVDQDIENDL 328
            |||..||||||:||.:||||||::||..|:|.||:||||||:||||||||:|||||||:.|..:|
 Frog   259 DSLGCDRLGCFNLSIRGHGECVQYVKSFNIPLLVLGGGGYTVRNVARCWTYETSLLVDETISEEL 323

  Fly   329 PATEYYDFFAPDFTLHPEINSRQDNANSKQYLELIVKHVYENLKMCQHSPSVQMVQTPPDVDLEE 393
            |.:||:::|||||||||::::|.:|.||:|||:.|.:.::|||||..|:||||:...|.|:
 Frog   324 PYSEYFEYFAPDFTLHPDVSTRIENQNSRQYLDQIRQTIFENLKMLNHAPSVQIHDVPSDI---- 384

  Fly   394 LRSNREEASDPDVRISVADEDKLVDAKNEFYDGDQDQDKPDSAE 437
            |...|.:..||:.|.| .|.....:|.|||||||.|.||....|
 Frog   385 LSYERTDEPDPEERGS-EDNYSRPEASNEFYDGDHDNDKESDVE 427

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HDAC3	NP_651978.2	HDAC3	4..388	CDD:212529	266/383 (69%)
hdac3	NP_001016883.1	HDAC3	3..383	CDD:212529	266/383 (69%)
		Histone deacetylase	3..316		231/316 (73%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	386..428		18/43 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	481	1.000	Domainoid score	I413
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H48250
Inparanoid	1	1.050	621	1.000	Inparanoid score	I864
OMA	1	1.010	-	-		QHG62154
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000617
OrthoInspector	1	1.000	-	-		oto102906
Panther	1	1.100	-	-	LDO	PTHR48252
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R9795
SonicParanoid	1	1.000	-	-		X4957
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	11.100