Protein Alignment HDAC3 and HDAC7

DIOPT Version :9

• Sequence 1: NP_651978.2
• Gene: HDAC3 / 44446
• FlyBaseID: FBgn0025825
• Length: 438
• Species: Drosophila melanogaster
• Sequence 2: XP_011536780.1
• Gene: HDAC7 / 51564
• HGNCID: 14067
• Length: 1035
• Species: Homo sapiens
• Alignment Length: 441
• Identity: 104/441 - (23%)
• Similarity: 174/441 - (39%)
• Gaps: 91/441 - (20%)

  Fly    23 HPMKPQRLAVTHSLVMNYGLHKKMKIYRPYKASAQDMLRFHSDEYIAY-----LQQVTPQNIQCN 82
            ||....|:....|.:...||..:.:..|..|||.:::...||:.::..     |.::...|.:..
Human   624 HPEHAGRIQSIWSRLQERGLRSQCECLRGRKASLEELQSVHSERHVLLYGTNPLSRLKLDNGKLA 688

  Fly    83 SVAYTKYLAHFSVGEDCPVFDGLFDFCAMYTGASLEGAQKLNHNHSDICINWSGGL--------- 138
            .:...:.......|                 |..::.....|..||.....|:.|.
Human   689 GLLAQRMFVMLPCG-----------------GVGVDTDTIWNELHSSNAARWAAGSVTDLAFKVA 736

  Fly   139 ---------------HHAKKFEASGFCYVNDIVIGILELLKYH--PRVLYIDIDVHHGDGVQEAF 186
                           |||....|.|||:.|.:.|...:|.:..  .::|.:|.|||||:|.|:.|
Human   737 SRELKNGFAVVRPPGHHADHSTAMGFCFFNSVAIACRQLQQQSKASKILIVDWDVHHGNGTQQTF 801

  Fly   187 YLTDRVMTASFHKY--GNYFFPGTGDMYEIGAESGRYYSVNVPLKEGID----DQSYFQVFKPII 245
            |....|:..|.|::  || ||||:|.:.|:||.||..::|||....|:|    |..|...|:.::
Human   802 YQDPSVLYISLHRHDDGN-FFPGSGAVDEVGAGSGEGFNVNVAWAGGLDPPMGDPEYLAAFRIVV 865

  Fly   246 SAIMDFYRPTAIVLQCGADSLAGD--RLGCFSLSTKGHGECVKFVKELNVPTLVVG-GGGYTLRN 307
            ..|...:.|..:::..|.|:..|.  .||.:.:|.|..|...:.:..|....:|:. .||:.|
Human   866 MPIAREFSPDLVLVSAGFDAAEGHPAPLGGYHVSAKCFGYMTQQLMNLAGGAVVLALEGGHDL-- 928

  Fly   308 VARCWTHE--TSLLVDQDIENDLPATEYYDFFAPDFTLHPEINSRQDNANSKQYLELIVK-H--- 366
            .|.|...|  .:.|:...::   |.:|             |...::.|.|:.:.||.::: |
Human   929 TAICDASEACVAALLGNRVD---PLSE-------------EGWKQKPNLNAIRSLEAVIRVHSKY 977

  Fly   367 --VYENLKMCQHSPSVQMVQTPPDVDLEELRSNREEASDPDVRISVADEDK 415
              ..:.|..|..|    .|...|..|.||:.:....||   :.:.:..||:
Human   978 WGCMQRLASCPDS----WVPRVPGADKEEVEAVTALAS---LSVGILAEDR 1021

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HDAC3	NP_651978.2	HDAC3	4..388	CDD:212529	96/412 (23%)
HDAC7	XP_011536780.1	HDAC7	601..978	CDD:212532	92/389 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0123
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810