Protein Alignment HDAC3 and Hdac10

DIOPT Version :10

• Sequence 1: NP_651978.2
• Gene: HDAC3 / 44446
• FlyBaseID: FBgn0025825
• Length: 438
• Species: Drosophila melanogaster
• Sequence 2: NP_001401901.1
• Gene: Hdac10 / 362981
• RGDID: 1305874
• Length: 666
• Species: Rattus norvegicus
• Alignment Length: 319
• Identity: 82/319 - (25%)
• Similarity: 142/319 - (44%)
• Gaps: 51/319 - (15%)

  Fly    27 PQRLAVTHSLVMNYGLHKKMKIYRPYKASAQDMLRFHSDEYIAYLQQ---VTPQNIQCNSVAY-- 86
            |:||......:...||.::.:.....:||.:::...||.||||.:|:   :..:.:...|..|
  Rat    28 PERLTAALDGLRQRGLEERCQCLSVCEASEEELGLVHSPEYIALVQKTQTLDKEELHTLSKQYDA 92

  Fly    87 ------TKYLAHFSVGEDCPVFDGLFDFCAMYTGASLEGAQKLNHNHSDICINWSGGLHHAKKFE 145
                  |.:.|..:.|....:.|      |:.|||.          |:.:.:....| ||:::..
  Rat    93 VYFHPDTFHCARLAAGAALRLVD------AVLTGAV----------HNGVALVRPPG-HHSQRAA 140

  Fly   146 ASGFCYVNDIVIGILELLKYH--PRVLYIDIDVHHGDGVQEAFYLTDRVMTASFHKY--GNY--F 204
            |:|||..|::.|......:.:  .|:|.:|.|||||.|:|..|.....|:..|:|:|  ||:  |
  Rat   141 ANGFCVFNNVAIAARHAKQKYGLQRILIVDWDVHHGQGIQYIFEDDPSVLYFSWHRYEHGNFWPF 205

  Fly   205 FPGTGDMYEIGAESGRYYSVNVPLKE-GIDDQSYFQVFKPIISAIMDFYRPTAIVLQCGADSLAG 268
            .| ..|...:|...|:.::||:|..: |:.:..|...|..::..:...:.|..:::..|.||..|
  Rat   206 LP-ESDADTVGRGRGQGFTVNLPWNQVGMGNADYLAAFLHVLLPLAFEFDPELVLVSAGFDSAIG 269

  Fly   269 DRLGCFSLSTKGHGECVKFVKELNVPTLVVGG-------GGYTLRNVAR--CWTHETSL 318
            |..|    ..:...||...:.:|  ..::.||       |||.|.::|:  |...:|.|
  Rat   270 DPEG----QMQATPECFAHLTQL--LQVLAGGRICAVLEGGYHLESLAQSVCMMVQTLL 322

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HDAC3	NP_651978.2	HDAC3	4..388	CDD:212529	82/319 (26%)
Hdac10	NP_001401901.1	Arginase_HDAC	18..354	CDD:450134	82/319 (26%)