Protein Alignment HDAC3 and hos2

DIOPT Version :10

• Sequence 1: NP_651978.2
• Gene: HDAC3 / 44446
• FlyBaseID: FBgn0025825
• Length: 438
• Species: Drosophila melanogaster
• Sequence 2: NP_594079.1
• Gene: hos2 / 2543643
• PomBaseID: SPAC3G9.07C
• Length: 434
• Species: Schizosaccharomyces pombe
• Alignment Length: 418
• Identity: 215/418 - (51%)
• Similarity: 292/418 - (69%)
• Gaps: 13/418 - (3%)

  Fly     4 RRVSYFYNADVGNFHYGAGHPMKPQRLAVTHSLVMNYGLHKKMKIYRPYKASAQDMLRFHSDEYI 68
            :||:|..:..|||:|||..|||||.|:.:|:.|||.||||.||.::.|..|:..:|..||.::|:
pombe    26 KRVTYHLDEQVGNYHYGDKHPMKPHRITITNHLVMGYGLHNKMSVFSPRMATFGEMSEFHREDYL 90

  Fly    69 AYLQQVTPQNIQCNSVAYTKYLAHFSVGEDCPVFDGLFDFCAMYTGASLEGAQKLNHNHSDICIN 133
            .:|::|||.|.:    .:......|::|:|||||||.::|.....||||:.::||....:||.||
pombe    91 DFLKRVTPDNAE----QFADKFQQFNIGDDCPVFDGTYEFSQRSAGASLDASRKLVQGQTDIAIN 151

  Fly   134 WSGGLHHAKKFEASGFCYVNDIVIGILELLKYHPRVLYIDIDVHHGDGVQEAFYLTDRVMTASFH 198
            |||||||||:.||||||||||||:.||.:|::.|||||||||:|||||||:|||.:|||:|.|||
pombe   152 WSGGLHHAKRGEASGFCYVNDIVLAILNMLRFFPRVLYIDIDIHHGDGVQQAFYESDRVLTVSFH 216

  Fly   199 KYGNYFFPGTGDMYEIGAESGRYYSVNVPLKEGIDDQSYFQVFKPIISAIMDFYRPTAIVLQCGA 263
            ||...|||.||:..|.|.:.|:|:::||||::||.|:.|..:||.||...::.::|:||||||||
pombe   217 KYNGDFFPATGNFDENGVKGGKYFALNVPLEDGIGDEQYTSLFKSIIEPTINTFQPSAIVLQCGA 281

  Fly   264 DSLAGDRLGCFSLSTKGHGECVKFVKELNVPTLVVGGGGYTLRNVARCWTHETSLLVDQDIENDL 328
            |||..||||.|:||...|||||:|.:..|:|.|||||||||||||||.|.:|||:.|::.|.::|
pombe   282 DSLGYDRLGVFNLSIHAHGECVRFTRSFNIPMLVVGGGGYTLRNVARAWCYETSICVNEQIPSEL 346

  Fly   329 P-ATEYYDFFAPDFTLHPEINSRQDNANSKQYLELIVKHVYENLKMCQHSPSVQMVQTPPDVDLE 392
            | .|.||:|||||:||||.:.::.:|.|:.:.||.:.....|.|:....:|||||.|.|||
pombe   347 PRETLYYEFFAPDYTLHPRLTTKIENKNTPKALEDLRIRALEQLRYLGGAPSVQMQQIPPD---- 407

  Fly   393 ELRSNREEASDPDVRISVADEDKLVDAK 420
             |..:.||   .|.|::....||.||.:
pombe   408 -LTGHLEE---EDERLNDEYLDKAVDVR 431

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HDAC3	NP_651978.2	HDAC3	4..388	CDD:212529	204/384 (53%)
hos2	NP_594079.1	HDAC_Hos2	28..337	CDD:212540	174/312 (56%)