Protein Alignment HDAC3 and clr6

DIOPT Version :9

• Sequence 1: NP_651978.2
• Gene: HDAC3 / 44446
• FlyBaseID: FBgn0025825
• Length: 438
• Species: Drosophila melanogaster
• Sequence 2: NP_595333.1
• Gene: clr6 / 2540368
• PomBaseID: SPBC36.05c
• Length: 405
• Species: Schizosaccharomyces pombe
• Alignment Length: 409
• Identity: 223/409 - (54%)
• Similarity: 298/409 - (72%)
• Gaps: 15/409 - (3%)

  Fly     4 RRVSYFYNADVGNFHYGAGHPMKPQRLAVTHSLVMNYGLHKKMKIYRPYKASAQDMLRFHSDEYI 68
            ::|||||:.||||:|||..|||||.|:.:.|:||:||.|::|:.:..|.:|:..||.|.|:||||
pombe     6 KKVSYFYDEDVGNYHYGPQHPMKPHRVRMVHNLVVNYNLYEKLNVITPVRATRNDMTRCHTDEYI 70

  Fly    69 AYLQQVTPQNIQCNSVAYTKYLAH---FSVGEDCPVFDGLFDFCAMYTGASLEGAQKLNHNHSDI 130
            .:|.:|||..::       |:..|   |:||:||||||||::||::..|.|:..||:||..:::|
pombe    71 EFLWRVTPDTME-------KFQPHQLKFNVGDDCPVFDGLYEFCSISAGGSIGAAQELNSGNAEI 128

  Fly   131 CINWSGGLHHAKKFEASGFCYVNDIVIGILELLKYHPRVLYIDIDVHHGDGVQEAFYLTDRVMTA 195
            .|||:||||||||.|||||||||||.:..|||||||.|||||||||||||||:|.||.||||||.
pombe   129 AINWAGGLHHAKKREASGFCYVNDIALAALELLKYHQRVLYIDIDVHHGDGVEEFFYTTDRVMTC 193

  Fly   196 SFHKYGNYFFPGTGDMYEIGAESGRYYSVNVPLKEGIDDQSYFQVFKPIISAIMDFYRPTAIVLQ 260
            ||||:|.| |||||.:.:.|..:|:.|:|||||::||||:||..||||:||.||.::||.|::||
pombe   194 SFHKFGEY-FPGTGHIKDTGIGTGKNYAVNVPLRDGIDDESYESVFKPVISHIMQWFRPEAVILQ 257

  Fly   261 CGADSLAGDRLGCFSLSTKGHGECVKFVKELNVPTLVVGGGGYTLRNVARCWTHETSLLVDQDIE 325
            ||.|||||||||||:||.|||..||.|||..|:|.:.|||||||:|||||.||:||.||..::::
pombe   258 CGTDSLAGDRLGCFNLSMKGHSMCVDFVKSFNLPMICVGGGGYTVRNVARVWTYETGLLAGEELD 322

  Fly   326 NDLPATEYYDFFAPDFTLHPEINSRQDNANSKQYLELIVKHVYENLKMCQHSPSVQMVQTPPDVD 390
            .:||..:|..::.||:.|: .:::..:|.|::|||:.|...:.|||:....:|||||.:||.|..
pombe   323 ENLPYNDYLQYYGPDYKLN-VLSNNMENHNTRQYLDSITSEIIENLRNLSFAPSVQMHKTPGDFT 386

  Fly   391 LEELRSN---REEASDPDV 406
            .|.....   :||..|..|
pombe   387 FENAEKQNIAKEEIMDERV 405

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HDAC3	NP_651978.2	HDAC3	4..388	CDD:212529	217/386 (56%)
clr6	NP_595333.1	PTZ00063	5..403	CDD:240251	221/405 (55%)
		RPD3-like	5..379	CDD:212528	214/381 (56%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0123
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000617
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100248
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	5	4.670