Protein Alignment HDAC3 and Hdac11

DIOPT Version :9

• Sequence 1: NP_651978.2
• Gene: HDAC3 / 44446
• FlyBaseID: FBgn0025825
• Length: 438
• Species: Drosophila melanogaster
• Sequence 2: NP_659168.1
• Gene: Hdac11 / 232232
• MGIID: 2385252
• Length: 347
• Species: Mus musculus
• Alignment Length: 327
• Identity: 82/327 - (25%)
• Similarity: 126/327 - (38%)
• Gaps: 64/327 - (19%)

  Fly    37 VMNYGLHKKM----KIYRPYKASAQDMLRFHSDEY---------IAYLQQVTPQNIQCNSVAYTK 88
            |:|:...:|:    .:....:||.:|:|..|:..|         :|.:.::.|.....|.:...|
Mouse    45 VINFLKEEKLLSDGMLVEAREASEEDLLVVHTRRYLNELKWSFVVATITEIPPVIFLPNFLVQRK 109

  Fly    89 YLAHFSVGEDCPVFDGLFDFCAMYTGASLEGAQKLNHNHSDICINWSGGLHHAKKFEASGFCYVN 153
            .|.....                .||.::. |.||..... ..||..||.||.......|||...
Mouse   110 VLRPLRT----------------QTGGTIM-AGKLAVERG-WAINVGGGFHHCSSDRGGGFCAYA 156

  Fly   154 DIVIGI---LELLKYHPRVLYIDIDVHHGDGVQEAFYLTDRVMTASFHKYGNYFFPGTGDMYEIG 215
            ||.:.|   .|.::...|...||:|.|.|:|.:..|....||.....  |..:.:||.    ...
Mouse   157 DITLAIKFLFERVEGISRATIIDLDAHQGNGHERDFMGDKRVYIMDV--YNRHIYPGD----RFA 215

  Fly   216 AESGRYYSVNVPLKEGIDDQSYFQVFKPIISAIMDFYRPTAIVLQCGADSLAGDRLGCFSLSTKG 280
            .|:.|.   .|.|:.|.:|:.|.:..:..:...:..:.|..:|...|.|.|.|||||..|:|..|
Mouse   216 KEAIRR---KVELEWGTEDEEYLEKVERNVRRSLQEHLPDVVVYNAGTDVLEGDRLGGLSISPAG 277

  Fly   281 ---HGECV-KFVKELNVPTLVVGGGGYTLRNVARCWTHETSLLVDQDIEN--DLPATEYYDFFAP 339
               ..|.| :.|:..::|.|:|..|||..|         |:.::...|.|  ||      ....|
Mouse   278 IVKRDEVVFRVVRAHDIPILMVTSGGYQKR---------TARIIADSILNLHDL------GLIGP 327

  Fly   340 DF 341
            :|
Mouse   328 EF 329

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HDAC3	NP_651978.2	HDAC3	4..388	CDD:212529	82/327 (25%)
Hdac11	NP_659168.1	Histone deacetylase	14..318		77/308 (25%)
		HDAC_classIV	35..319	CDD:212519	77/309 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0123
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810