Protein Alignment HDAC3 and Hdac10

DIOPT Version :9

• Sequence 1: NP_651978.2
• Gene: HDAC3 / 44446
• FlyBaseID: FBgn0025825
• Length: 438
• Species: Drosophila melanogaster
• Sequence 2: XP_006520600.1
• Gene: Hdac10 / 170787
• MGIID: 2158340
• Length: 667
• Species: Mus musculus
• Alignment Length: 419
• Identity: 103/419 - (24%)
• Similarity: 170/419 - (40%)
• Gaps: 82/419 - (19%)

  Fly    27 PQRLAVTHSLVMNYGLHKKMKIYRPYKASAQDMLRFHSDEYIAYLQQVTPQNI----------QC 81
            |:||......:...||.::.......:||.:::...||.||||.:|:.  |.:          |.
Mouse    28 PERLTAALDGLRQRGLEERCLCLSACEASEEELGLVHSPEYIALVQKT--QTLDKEELHALSKQY 90

  Fly    82 NSVAY---TKYLAHFSVGEDCPVFDGLFDFCAMYTGASLEGAQKLNHNHSDICINWSGGLHHAKK 143
            |:|.:   |.:.|..:.|....:.|      |:.|||.          |:.:.:....| ||:::
Mouse    91 NAVYFHPDTFHCARLAAGAALQLVD------AVLTGAV----------HNGLALVRPPG-HHSQR 138

  Fly   144 FEASGFCYVNDIVIGILELLKYH--PRVLYIDIDVHHGDGVQEAFYLTDRVMTASFHKY--GNY- 203
            ..|:|||..|::.:......:.:  .|:|.:|.|||||.|:|..|.....|:..|:|:|  |::
Mouse   139 AAANGFCVFNNVALAAKHAKQKYGLQRILIVDWDVHHGQGIQYIFNDDPSVLYFSWHRYEHGSFW 203

  Fly   204 -FFPGTGDMYEIGAESGRYYSVNVPLKE-GIDDQSYFQVFKPIISAIMDFYRPTAIVLQCGADSL 266
             |.| ..|...:|...|:.::||:|..: |:.:..|...|..::..:...:.|..:::..|.||.
Mouse   204 PFLP-ESDADAVGQGQGQGFTVNLPWNQVGMGNADYLAAFLHVLLPLAFEFDPELVLVSAGFDSA 267

  Fly   267 AGDRLGCFSLSTKGHGECVKFVKELNVPTLVVGG-------GGYTLRNVAR--CWTHETSLLVDQ 322
            .||..|    ..:...||...:.:|  ..::.||       |||.|.::|:  |...:| ||.|
Mouse   268 IGDPEG----QMQATPECFAHLTQL--LQVLAGGRICAVLEGGYHLESLAQSVCMMVQT-LLGD- 324

  Fly   323 DIENDLPATEYYDFFAPDFTLHPEINSRQDNANSKQYLELIVKHVYENLKMCQHSPSVQMVQTPP 387
                  |.........|..:....|.|.|  .....|...:.::|...|....|||
Mouse   325 ------PTPPLLGLMVPCQSALESIQSVQ--TAQTPYWTSLQQNVAPVLSSSTHSP--------- 372

  Fly   388 DVDLEELRSNREEASDPDVRISVADEDKL 416
                 |.||.|.....|...::   ||.|
Mouse   373 -----EERSLRLLGESPTCAVA---EDSL 393

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HDAC3	NP_651978.2	HDAC3	4..388	CDD:212529	95/389 (24%)
Hdac10	XP_006520600.1	Arginase_HDAC	18..354	CDD:388375	89/361 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0123
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810