Protein Alignment HDAC3 and HDAC11

DIOPT Version :10

• Sequence 1: NP_651978.2
• Gene: HDAC3 / 44446
• FlyBaseID: FBgn0025825
• Length: 438
• Species: Drosophila melanogaster
• Sequence 2: XP_321350.6
• Gene: HDAC11 / 1281439
• VectorBaseID: AGAMI1_010447
• Length: 361
• Species: Anopheles gambiae
• Alignment Length: 362
• Identity: 87/362 - (24%)
• Similarity: 133/362 - (36%)
• Gaps: 78/362 - (21%)

  Fly     5 RVSYFYNADVGNFHYGAG--HPMKP------QRLAVTHSLVMNYGLHKKMKIYRPYKASAQDMLR 61
            |:...|..:.|....|..  ||...      .||..|:.|:...|     .:|.|.:.:.:::|.
Mosquito    44 RIPIVYRPEYGVRFLGLQKLHPFDAAKGGNIYRLLKTNGLIQTDG-----DVYAPNEITLEELLA 103

  Fly    62 FHSDEYI---------AYLQQVTPQNIQCNSVAYTKYLAHFSVGEDCPVFDGLFDFCAMYTGASL 117
            .|:..||         |.:.::.|.....|......||.        |:        ...||.||
Mosquito   104 VHTQRYIDSLKWSLNVAKIAEIPPLLFVPNCFVQRSYLR--------PM--------RYQTGGSL 152

  Fly   118 EGAQKLNHNHSDICINWSGGLHHAKKFEASGFCYVNDIVIGILELL---KYHPRVLYIDIDVHHG 179
            ..|:....:.....||..||.||.......|||...||.:.:..|.   |...|:|.:|:|.|.|
Mosquito   153 LAARAALESGLGWAINLGGGFHHCSADRGGGFCPYADITLAVKMLQSSGKGIERILIVDLDAHQG 217

  Fly   180 DGVQEAFYLTDRVMTASFHKYGNYFFPGTGDMYEIGAESGRYYSVN----------VPLKEGIDD 234
            :|.:.......||.....:.|                   |.|..:          |.||...||
Mosquito   218 NGYERDLMEDRRVFILDMYNY-------------------RIYPRDQHAKLAIRRAVELKPHTDD 263

  Fly   235 QSYFQVFKPIISAIMDFYRPTAIVLQCGADSLAGDRLGCFSLSTKGHGECVKFV----KELNVPT 295
            :.|.:..|..:|..:..:.|..|:...|.|.|.||.||...::.:|..|..:||    .|.::|.
Mosquito   264 EEYLRKLKHCLSQSIAEFEPNFIIYNAGTDILKGDPLGLLDITPEGVVERDEFVFRSALERSIPL 328

  Fly   296 LVVGGGGYTLRNVARCWTHETSLLVDQDIENDLPATE 332
            :::..||| ||:.||...:....|.|:.:   ||..:
Mosquito   329 VMLLSGGY-LRSSARVIANSIVNLRDKAL---LPTVQ 361

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HDAC3	NP_651978.2	HDAC3	4..388	CDD:212529	87/362 (24%)
HDAC11	XP_321350.6	None