Protein Alignment HDAC3 and hdac12

DIOPT Version :10

• Sequence 1: NP_651978.2
• Gene: HDAC3 / 44446
• FlyBaseID: FBgn0025825
• Length: 438
• Species: Drosophila melanogaster
• Sequence 2: XP_001920667.4
• Gene: hdac12 / 100148903
• ZFINID: ZDB-GENE-131121-613
• Length: 354
• Species: Danio rerio
• Alignment Length: 305
• Identity: 77/305 - (25%)
• Similarity: 128/305 - (41%)
• Gaps: 74/305 - (24%)

  Fly    32 VTHSLVMNYGLHKKMKIYRPYKASAQDMLR-FHSDEYIAYLQQVTPQNIQCNSVAYTKYLAHFSV 95
            :..||:.:..:..| :::.| |.:::::|| .|::|                      ||::|..
Zfish    77 ILESLLRDQAITDK-QVWAP-KIASEELLRCVHTEE----------------------YLSNFIS 117

  Fly    96 GE---------DCPVFDGLFDFCAMYTGASLEGAQ-KLNHNHSDICINWSGGLHHAKKFEASGFC 150
            |:         ..|...||...|...||.:|...| .|...   :..:.:||.|||.....||||
Zfish   118 GKISEKDQKRSGFPWSSGLVQRCRYETGGTLLAGQIALQRG---LACSTAGGTHHAFPSHGSGFC 179

  Fly   151 YVNDIVIGILELLKYHP----RVLYIDIDVHHGDGVQEAFYLTDR--VMTASFHKYGNYFFPGTG 209
            .:||:.:....|:. .|    ::|.:|:|||.|||.  ||...|.  |.|.|.|...|  ||...
Zfish   180 LLNDLAVTAKHLIS-EPTPKRKILIVDLDVHQGDGT--AFIFKDEPSVFTFSVHCQRN--FPLRK 239

  Fly   210 DMYEIGAESGRYYSVNVPLKEGIDDQSYFQVFKPIISAIMDFYRPTAIVLQCGADSLAGDRLGCF 274
            ...::          :|.|::|.:|:.|....:..:..:::.:||..::...|.|....|.||..
Zfish   240 QQSDL----------DVSLEDGTEDREYLSRVQEHLPWLLESFRPDLVLYDSGVDPHWDDELGKL 294

  Fly   275 SLSTKG---------HGECVKFVKELNVPTLVVGGGGYTLRNVAR 310
            .|:.:|         |     .|.:..:|...|.||||: |::.|
Zfish   295 RLTDEGLYRRDLYVLH-----TVVKSGIPVATVIGGGYS-RDIDR 333

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HDAC3	NP_651978.2	HDAC3	4..388	CDD:212529	77/305 (25%)
hdac12	XP_001920667.4	HDAC_classIV	67..342	CDD:212519	77/305 (25%)