Protein Alignment HDAC3 and hdac8

DIOPT Version :10

• Sequence 1: NP_651978.2
• Gene: HDAC3 / 44446
• FlyBaseID: FBgn0025825
• Length: 438
• Species: Drosophila melanogaster
• Sequence 2: NP_001120462.1
• Gene: hdac8 / 100145561
• XenbaseID: XB-GENE-5863426
• Length: 369
• Species: Xenopus tropicalis
• Alignment Length: 353
• Identity: 150/353 - (42%)
• Similarity: 236/353 - (66%)
• Gaps: 20/353 - (5%)

  Fly    27 PQRLAVTHSLVMNYGLHKKMKIYRPYKASAQDMLRFHSDEYIAYLQQVT-------PQNIQCNSV 84
            |:|.::.|||:..|||.|:|::.:|..||.::|..||:|.|:.:|.:|:       |:.::
 Frog    27 PRRASMVHSLIEAYGLLKEMRVVKPKVASMEEMAAFHTDSYLQHLHKVSEEGDNDDPETLE---- 87

  Fly    85 AYTKYLAHFSVGEDCPVFDGLFDFCAMYTGASLEGAQKLNHNHSDICINWSGGLHHAKKFEASGF 149
                    :.:|.|||:.:|::|:.|...||:|..|::|....:.|.|||.||.|||||.|||||
 Frog    88 --------YGLGYDCPITEGIYDYAAAVGGATLTAAEQLMAGKTRIAINWPGGWHHAKKDEASGF 144

  Fly   150 CYVNDIVIGILELLKYHPRVLYIDIDVHHGDGVQEAFYLTDRVMTASFHKYGNYFFPGTGDMYEI 214
            ||:||.|:|||:|.:...||||:|:|:||||||::||..|.:|||.|.||:...|||||||:.:|
 Frog   145 CYLNDAVLGILKLREKFDRVLYVDMDLHHGDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDVSDI 209

  Fly   215 GAESGRYYSVNVPLKEGIDDQSYFQVFKPIISAIMDFYRPTAIVLQCGADSLAGDRLGCFSLSTK 279
            |...||||||||||::||.|:.|:|:.:.::..:...:.|.|:|||.|||::|||.:..|:::.:
 Frog   210 GLGKGRYYSVNVPLQDGIQDEKYYQICEGVLKEVFTTFNPEAVVLQLGADTIAGDPMCSFNMTPQ 274

  Fly   280 GHGECVKFVKELNVPTLVVGGGGYTLRNVARCWTHETSLLVDQDIENDLPATEYYDFFAPDFTLH 344
            |.|:|:|:|.:..:|||::|||||.|.|.|||||:.|:|:|.:.:.:::|..|::..:.||:.|.
 Frog   275 GIGKCLKYVLQWQLPTLILGGGGYHLPNTARCWTYLTALIVGRTLSSEIPDHEFFTEYGPDYVLE 339

  Fly   345 PEINSRQDNANSKQYLELIVKHVYENLK 372
            ...:.|.|. |..|.::.|::.:..:||
 Frog   340 VTPSCRPDR-NDSQKVQEILQSIKGHLK 366

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HDAC3	NP_651978.2	HDAC3	4..388	CDD:212529	150/353 (42%)
hdac8	NP_001120462.1	Histone deacetylase	5..316		137/300 (46%)
		HDAC8	7..369	CDD:212524	150/353 (42%)